Rapid detection of α-amanitin and β-amanitin in rat plasma by ultra-performance liquid chromatography–tandem mass spectrometry and its application to the toxicokinetic study of Lepiota brunneoincarnata

2021 ◽  
Author(s):  
Zhengsheng Mao ◽  
Youjia Yu ◽  
Hao Sun ◽  
Yue Cao ◽  
Qiaoyan Jiang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Rapid Detection ◽  
Ultra Performance Liquid Chromatography ◽  
Rat Plasma ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

scholarly journals Detection of Carbapenemase-Producing Bacteria by Using an Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method

2013 ◽  
Vol 58 (2) ◽  
pp. 1231-1234 ◽  
Author(s):  
Anne Carricajo ◽  
Paul O. Verhoeven ◽  
Salim Guezzou ◽  
Nathalie Fonsale ◽  
Gerald Aubert
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Rapid Detection ◽  
Ultra Performance Liquid Chromatography ◽  
Tandem Mass ◽  
Spectrometry Method ◽  
Content Type ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

ABSTRACTThe emergence of carbapenemase-producing bacteria poses a new challenge in the management of antibiotic therapies for patients. This report describes a new method using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for rapid detection of carbapenemase activity in enterobacteria,Pseudomonas aeruginosa, andAcinetobacter baumannii. In a panel of 78 isolates, including 41 carbapenemase-producing strains, the ULPC-MS/MS assay showed 100% agreement with molecular characterization, whereas six carbapenemase-producing isolates were not detected by the modified Hodge test.

Simultaneous determination of ivabradine, metoprolol and their metabolites in rat plasma by ultra-performance liquid chromatography tandem mass spectrometry and its application in a pharmacokinetic study

2015 ◽  
Vol 7 (19) ◽  
pp. 8459-8465 ◽  
Author(s):  
Wei Sun ◽  
Ruimin Chen ◽  
Wanshu Li ◽  
Hui Zhang ◽  
Jifeng Ye ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Pharmacokinetic Study ◽  
Ultra Performance Liquid Chromatography ◽  
Rat Plasma ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

A sensitive and rapid UPLC-MS/MS method was developed to determine ivabradine, metoprolol and their corresponding metabolites in rat plasma simultaneously.

Sign in / Sign up

Export Citation Format

Share Document