Detection of Carbapenemase-Producing Bacteria by Using an Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method
2013 ◽
Vol 58
(2)
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pp. 1231-1234
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Keyword(s):
ABSTRACTThe emergence of carbapenemase-producing bacteria poses a new challenge in the management of antibiotic therapies for patients. This report describes a new method using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for rapid detection of carbapenemase activity in enterobacteria,Pseudomonas aeruginosa, andAcinetobacter baumannii. In a panel of 78 isolates, including 41 carbapenemase-producing strains, the ULPC-MS/MS assay showed 100% agreement with molecular characterization, whereas six carbapenemase-producing isolates were not detected by the modified Hodge test.
2019 ◽
Vol 169
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pp. 279-287
2011 ◽
Vol 879
(24)
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pp. 2443-2453
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2013 ◽
Vol 8
(5)
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pp. 312-317
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2011 ◽
Vol 59
(18)
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pp. 9800-9805
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2011 ◽
Vol 56
(1)
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pp. 78-85
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