scholarly journals Disease Burden of Medial Epicondylitis in the USA Is Increasing: An Analysis of 19,856 Patients From 2007 to 2014

2018 ◽  
Vol 14 (3) ◽  
pp. 233-237 ◽  
Author(s):  
Anthony J. Wiggins ◽  
Jourdan M. Cancienne ◽  
Christopher L. Camp ◽  
Ryan M. Degen ◽  
David W. Altchek ◽  
...  
2020 ◽  
Author(s):  
Guan Rong Peng ◽  
Zhen Hua Guan ◽  
Qing Xi Zhang ◽  
Jia Xiang Gao ◽  
Wen Qun Rao ◽  
...  

Abstract Background: Among all osteoporotic fractures, hip fracture is common, carries high morbidity and mortality, thus has been becoming a vital concern We aim to analyze the present status and worldwide trends of hip fracture research in various clinical aspects. Methods: Publications from 2000 to 2019 were retrieved from Web of Science database and analyzed through bibliometric methodology. The software VOS viewer was utilized for visualized analysis. Results: Totally, 6139 publications were included, and publications increased annually, from 152 (2000) to 592 (2019). The USA has made huge contributions with the most publications, the highest H-index, and citations. Osteoporosis International has published the most papers. Leading researchers, contributing institutions, their cooperation relationships and scientific masterpieces have been identified. Research could be divided into five clusters: "mortality", "surgical management", “rehabilitation”, “osteoporosis” and "epidemiology". A clear developing trend was described, which initiated from fracture epidemiology and prevention, transitioned to perioperative management, orthogeriatric care and patient safety, and then to functional recovery, disease burden along with national audit and initiatives in recent time. Conclusions: Hip fractures resulted in conditions that extend far beyond orthopaedics, concerning epidemiology & preventive medicine, internal medicine & endocrinology , as well as critical care and gerontology. And a growing volume of publications in the future could be expected.


Viruses ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 794 ◽  
Author(s):  
Alyssa B. Evans ◽  
Karin E. Peterson

The California serogroup (CSG) comprises 18 serologically and genetically related mosquito-borne orthobunyaviruses. Of these viruses, at least seven have been shown to cause neurological disease in humans, including the leading cause of pediatric arboviral encephalitis in the USA, La Crosse virus. Despite the disease burden from these viruses, much is still unknown about the CSG viruses. This review summarizes our current knowledge of the CSG viruses, including human disease and the mechanisms of neuropathogenesis.


2020 ◽  
Vol 64 (3) ◽  
pp. 355-373
Author(s):  
Anne Hagen Berg ◽  
Stuart S. Blume

It is commonly argued that the decision to introduce a new vaccine is properly based on objective and measurable criteria, including disease burden and efficacy of the vaccine. Moreover, new vaccines are to be introduced rapidly and globally: delay is difficult to justify. Historical studies of new vaccine introductions paint a rather different and more complex picture. The few studies comparing new vaccine introduction in different countries suggest that ‘evidence’ for the efficacy of a vaccine was commonly subjected to varying interpretations. This paper, based on analysis of the introduction of the measles–mumps–rubella (MMR) vaccine in Denmark and the Netherlands, takes this argument further. Though both countries are – and were – small welfare states with well-organised national immunisation programmes, both adopted MMR a full decade after its introduction in the USA. The paper suggests that the reasons for delaying, in each case, are a reasonable reflection of each country’s concerns, perceptions of the three diseases, and technological approaches already adopted. There were differences in each of these respects. The decision to adopt MMR, which each country eventually took, was significantly influenced by the political and ideological changes taking place in the 1980s, including a growing emphasis on costs and benefits, as well as the growing influence of the international context.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
C S Jones ◽  
G Higginbotham ◽  
A Gormley ◽  
K Jones ◽  
B G Main

Abstract Introduction Transoral robotic surgery (TORS) is increasingly used for the resection of oropharyngeal tumours. It is unclear if there is equitable access to this innovative technique worldwide, specifically in areas of greatest need. This study aimed to map the geographic distribution of publications on TORS and compare this to global disease burden. Method Systematic searches identified all studies of TORS from inception to 2018. The country of origin of each study was identified. The incidence and age standardised rate (ASR) of oropharyngeal cancer for each country was obtained from The Global Cancer Observatory (GLOBOCAN) database. World Bank classifications of countries by income level were obtained. Results A total of 132 studies were identified. The majority (96%) were published in high-income countries, 2% in lower-middle, and 2% in upper-middle income countries. Eighty-nine were published in the USA, the country with the second-highest incidence of oropharyngeal cancer worldwide (13% of total), but 20th by ASR. The greatest incidence was in India (21%), however this was the source of only 2% of studies. Of the ten countries with the highest incidence, eight were represented in published studies, in comparison to four of the top 10 by ASR. Conclusions There is evident disparity in the geographical distribution of published studies of TORS. This disparity may represent unequal access to surgical technologies, or a lack of evaluation of the technology in different healthcare settings. This may impact the generalisability of research findings. Equitable access to novel surgical technologies is ethical and can help address global disease burden.


2019 ◽  
Vol 35 (S1) ◽  
pp. 61-61
Author(s):  
Dionysios Kyriopoulos ◽  
Paul Sogokon ◽  
Christopher Teale ◽  
Luke Callan

IntroductionWe sought to examine patients’ perceptions of disease burden and treatment impact, and what patients value over the course of the asthma experience.MethodsPatient focus groups were conducted in three countries, the USA (n = 8 patients), the United Kingdom (n = 7 patients), and Germany (n = 7 patients), to examine aspects of disease burden and patient experience (physical, emotional, clinical, economic, and social). Cause and effect were also explored. Global Initiative for Asthma guidelines were used to screen patients by severity, based on age, sex, time since diagnosis, number of attacks, oral corticosteroid use, and number of therapies needed to control symptoms. Patients classified and ranked aspects of disease burden, including whether it was continuous or episodic in nature, and discussed the interventions used to manage their asthma.ResultsThe overall burden of illness was driven by the combined effect of the disease and treatment burdens. All patients highlighted the negative impact of oral corticosteroids. Patients believed that they were the key actors in their asthma management (not healthcare professionals), and reported the physical and emotional burdens as being the most dominant. Understanding of the terms “attack” or “exacerbation” differed significantly between patients, and did not necessarily match the clinical definitions. Patients considered asthma to be an individualized condition that drives lifestyle changes; disease management drives burden and vice versa. Patients perceived that burden was continuous over time, with specific phases of variable duration—before, during, and after an attack—whereas other stakeholders had a more episodic focus. Patients expected more holistic and personalized approaches for managing their asthma.ConclusionsThe research indicated a misalignment between what patients value and what clinicians, payers, and regulators consider in their assessments and decisions. Greater alignment among the different stakeholders, and more inclusion of patients’ values in decision making, will improve outcomes.


2016 ◽  
Vol 4 (12) ◽  
pp. 996-1003 ◽  
Author(s):  
Teresa M Attina ◽  
Russ Hauser ◽  
Sheela Sathyanarayana ◽  
Patricia A Hunt ◽  
Jean-Pierre Bourguignon ◽  
...  

2020 ◽  
Author(s):  
Guanrong Peng ◽  
Zhenhua Guan ◽  
Yunfei Hou ◽  
Jiaxiang Gao ◽  
Wenqun Rao ◽  
...  

Abstract Background Among all osteoporotic fractures, hip fracture is common and carries high morbidity and mortality. We aim to analyze the present status and worldwide trends of hip fracture research in various clinical aspects.Methods Publications from 2010 to 2019 were retrieved from Web of Science database and analyzed through bibliometric methodology. The software VOS viewer was utilized for visualized analysis.Results Totally, 6139 publications were included, and publications increased annually, from 152 (2000) to 592 (2019). The USA has made huge contributions with the most publications, the highest H-index, and citations. Osteoporosis International has published the most papers. Leading researchers, contributing institutions, their cooperation relationships and scientific masterpieces have been identified. Research could be divided into five clusters: "mortality", "surgical management", “rehabilitation”, “osteoporosis” and "epidemiology". A clear developing trend was described, which initiated from fracture epidemiology and prevention, transitioned to perioperative management, orthogeriatric care and patient safety, and then to functional recovery, disease burden along with national audit and initiatives in recent time.Conclusions Hip fractures resulted in conditions that extend far beyond orthopaedics, concerning epidemiology & preventive medicine, internal medicine & endocrinology, as well as critical care and gerontology. And a growing volume of publications in the future could be expected.


Work ◽  
2020 ◽  
pp. 1-6 ◽  
Author(s):  
Arthur A. Mirin ◽  
Mary E. Dimmock ◽  
Leonard A. Jason

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