Unmodified and positively charged gold nanoparticles for sensitive colorimetric detection of folate receptor via terminal protection of small molecule-linked ssDNA

2016 ◽  
Vol 59 (6) ◽  
pp. 770-775 ◽  
Author(s):  
Min Wang ◽  
Fangzhen Li ◽  
Bingying Jiang ◽  
Junqiang Xu ◽  
Shuo Li ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Folate Receptor ◽  
Colorimetric Detection ◽  
Positively Charged Gold Nanoparticles ◽  
Positively Charged

Gold nanoparticle-based exonuclease III signal amplification for highly sensitive colorimetric detection of folate receptor

Nanoscale ◽  
2014 ◽  
Vol 6 (6) ◽  
pp. 3055-3058 ◽  
Author(s):  
Xinjian Yang ◽  
Zhiqiang Gao
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Signal Amplification ◽  
Colorimetric Assay ◽  
Folate Receptor ◽  
Colorimetric Detection ◽  
Label Free ◽  
Exonuclease Iii ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

By combining terminal protection of small molecule (folate)-capped DNA probes, exonuclease III signal amplification and gold nanoparticles, we developed a simple and label-free colorimetric assay for highly sensitive detection of folate receptor.

A ratiometric colorimetric detection of the folate receptor based on terminal protection of small-molecule-linked DNA

The Analyst ◽  
2015 ◽  
Vol 140 (4) ◽  
pp. 1260-1264 ◽  
Author(s):  
Yanhong Zhu ◽  
Guangfeng Wang ◽  
Liang Sha ◽  
Yuwei Qiu ◽  
Hong Jiang ◽  
...  
Keyword(s):  
Small Molecule ◽  
Crucial Role ◽  
Folate Receptor ◽  
Low Cost ◽  
Colorimetric Detection ◽  
Cancer Therapeutics ◽  
Selective Detection

Development of strategies for the sensitive and selective detection of the folate receptor (FR) that are simple and low cost is of great importance for assessing cancer therapeutics due to its crucial role in physiological, pharmacological and pathological processes.

Positively charged gold nanoparticles capped with folate quaternary chitosan: Synthesis, cytotoxicity, and uptake by cancer cells

2018 ◽  
Vol 183 ◽  
pp. 140-150 ◽  
Author(s):  
Hui-ju Yen ◽  
Yen-an Young ◽  
Tsung-neng Tsai ◽  
Kuang-ming Cheng ◽  
Xin-an Chen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Positively Charged Gold Nanoparticles ◽  
Positively Charged

scholarly journals Colorimetric detection of protein via the terminal protection of small-molecule-linked DNA and unmodified gold nanoparticles

RSC Advances ◽  
2018 ◽  
Vol 8 (68) ◽  
pp. 38758-38764
Author(s):  
Jianwei Zhao ◽  
Cuiping Li ◽  
Guimin Ma ◽  
Wenhui Hao ◽  
Hongxia Jia
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Colorimetric Detection ◽  
Protein Detection ◽  
Target Protein

A novel colorimetric strategy for protein detection was developed based on unmodified gold nanoparticles (AuNPs) and terminal protection from a target protein.

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