Naked-eye sensitive detection of nuclease activity using positively-charged gold nanoparticles as colorimetric probes

2011 ◽  
Vol 47 (45) ◽  
pp. 12301 ◽  
Author(s):  
Rui Cao ◽  
Baoxin Li ◽  
Yuanfu Zhang ◽  
Zhining Zhang
Keyword(s):  
Gold Nanoparticles ◽  
Nuclease Activity ◽  
Sensitive Detection ◽  
Naked Eye ◽  
Positively Charged Gold Nanoparticles ◽  
Positively Charged

Naked-eye colorimetric detection of HCV RNA mediated by a 5′ UTR-targeted antisense oligonucleotide and plasmonic gold nanoparticles

The Analyst ◽  
2021 ◽  
Author(s):  
Almas Shamaila Mohammed ◽  
Aniket Balapure ◽  
Mahammad Nanne Khaja ◽  
Ramakrishnan Ganesan ◽  
Jayati Ray Dutta
Keyword(s):  
Gold Nanoparticles ◽  
Antisense Oligonucleotide ◽  
Early Stage ◽  
Colorimetric Detection ◽  
Sensitive Detection ◽  
Clinical Samples ◽  
Hcv Rna ◽  
Naked Eye

An Au NP based facile strategy for the rapid, early-stage, and sensitive detection of HCV RNA in clinical samples which avoids thiol tagging to the antisense oligonucleotide and expensive infrastructure is presented.

Positively charged gold nanoparticles capped with folate quaternary chitosan: Synthesis, cytotoxicity, and uptake by cancer cells

2018 ◽  
Vol 183 ◽  
pp. 140-150 ◽  
Author(s):  
Hui-ju Yen ◽  
Yen-an Young ◽  
Tsung-neng Tsai ◽  
Kuang-ming Cheng ◽  
Xin-an Chen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Positively Charged Gold Nanoparticles ◽  
Positively Charged

scholarly journals Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide

2019 ◽  
Vol 9 (22) ◽  
pp. 4782
Author(s):  
Berlina ◽  
Komova ◽  
Zherdev ◽  
Gaur ◽  
Dzantiev
Keyword(s):  
Gold Nanoparticles ◽  
Drinking Water ◽  
Detection Limit ◽  
Gold Nanoparticle ◽  
Variation Coefficient ◽  
Sensitive Detection ◽  
Naked Eye ◽  
Nanoparticle Surface ◽  
Colorimetric Measurements ◽  
Target Analyte

A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afforded after adding antimony ions, thus changing the solution color from pink to blue. The results of aptamer’s interaction on the gold nanoparticle surface with the target analyte can be detected either by photometry or by the naked eye. The realized assay provides rapid (2 min), sensitive (detection limit 10 ng/mL), specific, and precise (variation coefficient less than 3.8%) detection of antimony (III) in drinking water.

scholarly journals A label-free protamine-assisted colorimetric sensor for highly sensitive detection of S1 nuclease activity

The Analyst ◽  
2020 ◽  
Vol 145 (7) ◽  
pp. 2774-2778
Author(s):  
Jiahui Wen ◽  
Yongming Liu ◽  
Jingwen Li ◽  
Hao Lin ◽  
Yiran Zheng ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Method ◽  
Nuclease Activity ◽  
Colorimetric Sensor ◽  
Sensitive Detection ◽  
Label Free ◽  
S1 Nuclease ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A label-free, simple and rapid colorimetric method for the sensitive detection of S1 nuclease activity based on protamine-assisted aggregation of gold nanoparticles.

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