Magnetic resonance imaging (MRI) radiomics of papillary thyroid cancer (PTC): a comparison of predictive performance of multiple classifiers modeling to identify cervical lymph node metastases before surgery

Background: Tongue and floor malignancies can be diagnosed based on biopsy and clinical examination, but diagnostic imaging is essential to confirm and define the size and extent of the disease.Objectives: The aim of this study was to recognise and understand the extent and precision of the diagnostic accuracy of multi-detector row computed tomography (MDCT) and magnetic resonance imaging (MRI) in mandibular tumour involvement, cervical lymph node metastases, T staging of tongue and floor of mouth malignancies in order to represent the proper treatment plan.Methods: Fifty patients with histologically proven squamous cell carcinomas (SCC) of tongue and floor of mouth malignancies underwent both multi-detector row computed tomography and magnetic resonance imaging before surgery. Two radiologists independently, unaware of the findings, in consensus reviewed and interpreted all images to determine the extent of the primary tumour (T), mandibular tumour invasion and cervical lymph node metastasis. Imaging results obtained were correlated with postoperative histopathologic findings that represented our referencestandard. Cohen’s kappa index and McNemar test were used to verify the concordance between the two radiologists and above mentioned three study parameters.Results: Magnetic resonance imaging showed superiority to multi-detector row computed tomography in the evaluation of the T parameter staging of TNM classifi cation and medullary bone involvement while multi-detector row computed tomography was more accurate compared to magnetic resonance imaging in the visualization of small cortical bone erosions. However, both the modalities demonstrated similar diagnostic performance in detection of metastatic lymph nodes.Conclusion: Multi-detector row computed tomography and magnetic resonance imaging have nearly equal potential for detecting the tumour size, mandibular infiltration and nodal metastases.Journal of Kathmandu Medical College, Vol. 5, No. 4, Issue 18, Oct.-Dec., 2016, page:104-111

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Robot-Assisted Neck Dissection via a Transaxillary and Retroauricular Approach Versus a Conventional Transcervical Approach in Papillary Thyroid Cancer with Cervical Lymph Node Metastases

Journal of Laparoendoscopic & Advanced Surgical Techniques ◽

10.1089/lap.2013.0296 ◽

2014 ◽

Vol 24 (6) ◽

pp. 367-372 ◽

Cited By ~ 18

Author(s):

Won Shik Kim ◽

Yoon Woo Koh ◽

Hyung Kwon Byeon ◽

Young Min Park ◽

Hyo Jin Chung ◽

...

Keyword(s):

Thyroid Cancer ◽

Lymph Node ◽

Lymph Node Metastases ◽

Cervical Lymph Node ◽

Papillary Thyroid ◽

Robot Assisted ◽

Cervical Lymph Node Metastases ◽

Transcervical Approach ◽

Node Metastases ◽

Retroauricular Approach

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Preoperative Detection of Cervical Lymph Node Metastases in Papillary Thyroid Cancer: A Surgical Perspective

Onkologie ◽

10.1159/000255337 ◽

2009 ◽

Vol 32 (12) ◽

pp. 762-766 ◽

Cited By ~ 6

Author(s):

George H. Sakorafas ◽

Spiros Christodoulou ◽

Christos Lappas ◽

Michael Safioleas

Keyword(s):

Thyroid Cancer ◽

Lymph Node ◽

Papillary Thyroid Cancer ◽

Lymph Node Metastases ◽

Cervical Lymph Node ◽

Papillary Thyroid ◽

Cervical Lymph Node Metastases ◽

Node Metastases

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LEVELS I–VII FOLLOWING THYROIDECTOMY FOR PAPILLARY THYROID CANCER

Siberian Journal of Oncology ◽

10.21294/1814-4861-2020-19-5-76-81 ◽

2020 ◽

Vol 19 (5) ◽

pp. 76-81

Author(s):

V. S. Parshin ◽

A. A. Veselova ◽

V. S. Medvedev ◽

S. A. Ivanov ◽

A. D. Kaprin

Keyword(s):

Thyroid Cancer ◽

Lymph Node ◽

Lymph Nodes ◽

Papillary Thyroid Cancer ◽

Lymph Node Metastases ◽

Cervical Lymph Node ◽

Papillary Thyroid ◽

Cervical Lymph Nodes ◽

Cervical Lymph Node Metastases ◽

Node Metastases

Introduction. Cervical lymph node metastases can occur not only in patients when they are first diagnosed with papillary thyroid cancer but also in patients who have undergone thyroidectomy. Objective. The aim of this study was to assess the potential utility of neck ultrasound in diagnosing cervical lymph node metastases (levels I–VII) in patients who underwent surgical treatment for papillary thyroid cancer.Material and Methods. B-mode sonography of all nodal levels in the neck was performed using a linear array transducer in the frequency range of 7.5–13 MHz, power mapping and panoramic scan to locate regional lymph node metastases. All lymph nodes removed during reoperations were submitted for histological evaluation. Sonographic examinations of cervical lymph nodes of the levels I–VII were performed in 2875 patients who had undergone thyroidectomy in different regions of the Russian Federation. The patients were admitted to our clinic to receive radioactive iodine therapy. All neck levels were assessed by ultrasound.Results. Sonography revealed cervical lymph node metastases in 267 (9.2 %) of 2875 patients with papillary thyroid cancer who had undergone thyroidectomy. Nodal metastasis in level VI only occurred in 70 (2.4 %) patients, in levels II–III–IV only in 150 (5.21 %), in level VB only in 32 (1.11 %), and at the same time in level VI and in levels II–III–IV in 15 (0.52 %) patients. There were no metastases in levels I, VA, VII of the neck. Solitary metastases to all levels were found in 7.5 %, multiple metastases in 1.2 %, and conglomerates in 0.6 % of cases. Solitary metastases in level VI were noted in 56 (1.9 %), in levels II–III–IV in 125 (4.3 %), and in level VB in 29 (1.0 %) patients. Multiple metastases in level VI were detected in 11 (0.38 %), in levels II–III–IV in 21 (0.73 %), and in level VB in 3 (0.1 %) patients. Median metastasis size was 2.1 ± 1.6 cm.Conclusion. Post-thyroidectomy patients were found to have cervical lymph node metastases. Ultrasound scanning of the neck should be considered a key examination if there are cicatricial changes as it enables to identify metastasis and to determine its location. The maximal number of metastases was noted in levels II–III–IV. Cervical lymph node metastases occurred less frequently in the central level and level VB. The predominant metastatic pattern was solitary. There was an essential difference in metastatic spread to cervical lymph nodes between postthyroidectomy patients and patients who were first diagnosed with papillary thyroid cancer.

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