Assessment of 4DCT imaging findings of parathyroid adenomas in correlation with biochemical and histopathological findings

Author(s):  
Ekim Gumeler ◽  
Olcay Kurtulan ◽  
Sevtap Arslan ◽  
Jale Karakaya ◽  
Cenk Sokmensuer ◽  
...  
2019 ◽  
Vol 54 ◽  
pp. 40-47 ◽  
Author(s):  
Lena Naffaa ◽  
Ibrahim Khalifeh ◽  
Rida Salman ◽  
Malak Itani ◽  
Raya Saab ◽  
...  

2019 ◽  
Vol 6 (2) ◽  
pp. 419
Author(s):  
Ponnam Bharath Kumar ◽  
Prem Sai Reddy

Background: Newer imaging techniques have emerged, and it is necessary to study their accuracy in comparison to the gold standard of histopathology for increasing accuracy of diagnosis. Ovarian tumors are difficult to diagnose when they are of small size. But their diagnosis should be done at an earlier stage for effective outcome of the management of these tumors. The objective was to study accuracy of imaging findings compared with that of histopathological findings of the ovarian lesions.Methods: This study was done for a period of two years from December 2010 to May 2012. A total of 30 patients who were clinically suspected to have ovarian pathology were referred to us for ultrasonography. In 30 patients, who were referred for sonography a total of 36 ovarian masses was found? Each patient was examined by Trans abdominal sonography / Trans vaginal sonography, MRI (Pre and Post contrast) and CT when required.Results: Sonography could detect the origin of mass accurately in 29 (80.5 %) masses and MRI could detect the origin accurately in 34 (94.4%) masses. Sonography characterized 33/36 (91.6%) masses correctly. MRI correctly characterized 34/36 (94.5%) cases and tissue content was identified correctly. The sensitivity of imaging findings for correctly identifying malignant lesions was 100% and sensitivity for correctly making a benign diagnosis was 92.5%. The specificity of imaging findings for correctly identifying malignant lesion was 92% and specificity for correctly making a benign diagnosis was 84.6 %.Conclusions: MRI is significantly superior to US in all respects due to the excellent soft tissue contrast and organ-specific information generated in the pelvis.


Author(s):  
Julio Sepúlveda-Saavedra ◽  
Beatriz González-Corona ◽  
Víctor A. Tamez Rodríguez ◽  
Ma. Victoria Bermúdez de Rocha ◽  
Alfredo Piñeyro López

It has been shown in previous studies that the toxin T-514 isolated from K. humboldtiana induces severe damage to the lung in treated rodents. Histopathological findings include edema, and alveolar hemorrage. However, the ultraestructure of the lesion has not been investigated. In this study we used two species of rodents: Hamster and guinea pig, and a primate: Macaca fascicularis. Animals received different single dosis of the toxin via intraperitoneal. Control animals received only the vehicle (propylen glycol). Inmediately after spontaneous death, lung samples were fixed in Karnovsky-Ito fixative, post fixed in osmium tetroxide and embedded in epon. Thin sections were prepared with an Ultratome V LKB, stained with uranly acetate and lead citrate, and studied in an electron microscope Zeiss-EM109.


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