Risk Factors Associated with Lymph Node Metastasis for Early Gastric Cancer Patients Who Underwent Non-curative Endoscopic Resection: a Systematic Review and Meta-analysis

2018 ◽  
Vol 23 (7) ◽  
pp. 1318-1328 ◽  
Author(s):  
Bochao Zhao ◽  
Jingting Zhang ◽  
Jiale Zhang ◽  
Rui Luo ◽  
Zhenning Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Systematic Review ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Early Gastric Cancer ◽  
Meta Analysis ◽  
Factors Associated ◽  
Node Metastasis ◽  
Gastric Cancer Patients

scholarly journals Predictors of lymph node metastasis and residual tumor in early gastric cancer patients after noncurative endoscopic resection: a systematic review and meta-analysis

2020 ◽  
Vol 13 ◽  
pp. 175628482093503
Author(s):  
Bolun Jiang ◽  
Li Zhou ◽  
Jun Lu ◽  
Yizhi Wang ◽  
Junchao Guo
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Early Gastric Cancer ◽  
Tumor Size ◽  
Meta Analysis ◽  
Residual Tumor ◽  
Node Metastasis

Background: It is challenging to identify the prevalence of lymph node metastasis (LNM) and residual tumor in patients with early gastric cancer (EGC) who underwent noncurative endoscopic resection (ER). This present meta-analysis was aimed to establish imperative potential predictive factors in order to select the optimal treatment method. Methods: A systematic literature search of PubMed, Embase, and Cochrane Library databases was performed through 1 February 2019 to identify relevant studies, which investigated risk factors for LNM and residual tumor in patients with EGC who underwent noncurative ER. Eligible data were systematically reviewed through a meta-analysis. Results: Overall, 12 studies investigating the risk factor of LNM were included, totaling 3015 patients, 7 of which also involved cancer residues. After the present meta-analysis, six predictors, including tumor size >30 mm, tumor invasion depth (⩾500 μm from the muscularis mucosae), macroscopic appearance, undifferentiated histopathological type, positive vertical margin, and presence of lymphovascular invasion (including lymphatic invasion and vascular invasion) were significantly associated with LNM, whereas tumor size >30 mm, positive horizontal margin, and positive vertical margin were identified as significant predictors for the risk of residual tumor. No evidence of publication bias was observed. Conclusions: Six and three variables were established as significant risk factors for LNM and residual tumor in patients with EGC who underwent noncurative ER, respectively. Patients with EGC who present these risk factors after noncurative ER are strongly suggested to receive additional surgery, while others might be suitable for strict follow-up. This might shed some new light on the selection of follow-up treatment for noncurative ER.

scholarly journals Risk factors for lymph node metastasis in early gastric cancer patients: Report from Eastern Europe country– Lithuania

BMC Surgery ◽  
2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Rimantas Bausys ◽  
Augustinas Bausys ◽  
Indre Vysniauskaite ◽  
Kazimieras Maneikis ◽  
Dalius Klimas ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Early Gastric Cancer ◽  
Eastern Europe ◽  
Cancer Patients ◽  
Node Metastasis ◽  
Eastern Europe Country ◽  
Gastric Cancer Patients

601. Risk factors for lymph node metastasis in early gastric cancer patients in Lithuanian population

2016 ◽  
Vol 42 (9) ◽  
pp. S179-S180
Author(s):  
A. Baušys ◽  
D. Klimas ◽  
K. Maneikis ◽  
K. Pauža ◽  
E. Sangaila ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Early Gastric Cancer ◽  
Cancer Patients ◽  
Node Metastasis ◽  
Gastric Cancer Patients
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