The Impact of Bariatric Surgery Compared to Metformin Therapy on Pregnancy Outcomes in Patients with Polycystic Ovarian Syndrome: a Systematic Review and Meta-analysis

2021 ◽  
Vol 25 (2) ◽  
pp. 378-386
Author(s):  
Catherine Chang ◽  
Steven Chang ◽  
Jillian Poles ◽  
Violeta Popov
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Pregnancy Outcomes ◽  
Polycystic Ovarian Syndrome ◽  
Meta Analysis ◽  
Metformin Therapy ◽  
The Impact ◽  
Ovarian Syndrome

scholarly journals The effectiveness and safety of treatments used for polycystic ovarian syndrome management in adolescents: a systematic review and network meta-analysis protocol

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Reem A. Al Khalifah ◽  
Iván D. Flórez ◽  
Brittany Dennis ◽  
Binod Neupane ◽  
Lehana Thabane ◽  
...  
Keyword(s):  
Systematic Review ◽  
Polycystic Ovarian Syndrome ◽  
Meta Analysis ◽  
Ovarian Syndrome ◽  
Analysis Protocol

scholarly journals Association between melatonin receptor gene polymorphisms and polycystic ovarian syndrome: a systematic review and meta-analysis

2020 ◽  
Vol 40 (6) ◽  
Author(s):  
Shiqi Yi ◽  
Jiawei Xu ◽  
Hao Shi ◽  
Wenbo Li ◽  
Qian Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Single Nucleotide Polymorphisms ◽  
Polycystic Ovarian Syndrome ◽  
Meta Analysis ◽  
Genetic Models ◽  
Cochrane Library ◽  
Nucleotide Polymorphisms ◽  
Melatonin Receptor ◽  
Single Nucleotide ◽  
Ovarian Syndrome

Abstract Background: Polycystic ovarian syndrome (PCOS) is a kind of common gynecological endocrine disorder. And the mutations of melatonin receptor (MTNR) genes are related to the occurrence of PCOS. But previous researches have shown opposite results. So, the object of our systematic review and meta-analysis is to investigate the relationship between MTNR 1A/B polymorphisms and PCOS. Methods: PubMed, Embase, Ovid, the Cochrane Library, Web of Science and three Chinese databases (VIP, CNKI and Wanfang) were used to retrieve eligible articles published between January 1980 and February 2020. And we used the odds ratio (OR) and its 95% confidence interval (CI) to investigate the strength of the association by six genetic models, allelic, codominant (homozygous and heterozygous), dominant, recessive and superdominant models. Review Manager 5.3, IBM SPSS statistics 25 and Stata MP 16.0 software were used to do this meta-analysis. Results: Our meta-analysis involved 2553 PCOS patients and 3152 controls, for two single nucleotide polymorphisms (rs10830963 C> G in MTNR1B and rs2119882 T> C in MTNR1A) and significant associations were found in some genetic models of these single nucleotide polymorphisms (SNPs). For rs10830963, strongly significant was found in the heterozygote model (GC vs. CC, P=0.02). Additionally, a slight trend was detected in the allelic (G vs. C), homozygote (GG vs. CC) and dominant (GG+GC vs. CC) model of rs10830963 (P=0.05). And after further sensitivity analysis, a study with high heterogeneity was removed. In the allelic (P=0.000), homozygote (P=0.001), dominant (P=0.000) and recessive (GG vs. GC+CC, P=0.001) model, strong associations between rs10830963 and PCOS were found. Moreover, for rs2119882, five genetic models, allelic (C vs. T, P=0.000), codominant (the homozygote (CC vs. TT, P=0.000) and heterozygote model (CT vs. TT, P=0.02), dominant (CC + CT vs. TT, P=0.03) and recessive model (CC vs. CT + TT, P=0.000) showed significant statistical associations with PCOS. Conclusion: MTNR1B rs10830963 and MTNR1B rs2119882 polymorphisms are associated with PCOS risk. However, the above conclusions still require being confirmed by much larger multi-ethnic studies.

scholarly journals The impact of isolated non-cavity distorting intramural fibroids on pregnancy outcomes in in vitro fertilization cycles: a systematic review and meta-analysis

2019 ◽  
Vol 112 (3) ◽  
pp. e345
Author(s):  
Kiran Rikhraj ◽  
Justin Tan ◽  
Omur Taskin ◽  
Arianne Y.K. Albert ◽  
Catherine Allaire ◽  
...  
Keyword(s):  
Systematic Review ◽  
In Vitro Fertilization ◽  
Pregnancy Outcomes ◽  
Meta Analysis ◽  
Vitro Fertilization ◽  
The Impact ◽  
Intramural Fibroids

A443 Systematic review and meta-analysis of the impact of revisional bariatric surgery on obesity-related metabolic outcomes

2019 ◽  
Vol 15 (10) ◽  
pp. S181-S182
Author(s):  
Asim Shabbir ◽  
Zong Jie Koh ◽  
Claire Chew ◽  
Nicholas Syn ◽  
Guowei Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Meta Analysis ◽  
Revisional Bariatric Surgery ◽  
Metabolic Outcomes ◽  
The Impact

The impact of bariatric surgery on quality of life: a systematic review and meta-analysis

2015 ◽  
Vol 16 (8) ◽  
pp. 639-651 ◽  
Author(s):  
N. Lindekilde ◽  
B. P. Gladstone ◽  
M. Lübeck ◽  
J. Nielsen ◽  
L. Clausen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Bariatric Surgery ◽  
Meta Analysis ◽  
The Impact
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