Efficacy of Laparoscopic Sleeve Gastrectomy in Mildly Obese Patients with Body Mass Index of 30–35 kg/m2

Objective Myonectin, a newly discovered myokine, enhances fatty acid uptake in cultured adipocytes and hepatocytes and suppresses circulating levels of free fatty acids in mice. Recent studies showed that serum myonectin concentration is negatively correlated with obesity. This study was undertaken to evaluate the change of serum myonectin in obese patients after laparoscopic sleeve gastrectomy. Methods This study was performed in a population of 42 obese and 58 control subjects from April of 2018 to December of 2019. All obese subjects underwent laparoscopic sleeve gastrectomy. Anthropometric measurements, lipid profiles, HbA1c and serum myonectin were assessed at baseline and six months after laparoscopic sleeve gastrectomy. Results Serum myonectin concentrations were significantly lower in the obese patients than in the controls. Serum myonectin concentrations were increased at six months after laparoscopic sleeve gastrectomy. Simple linear regression analysis indicated that serum myonectin was negatively correlated with weight, waist circumference, hip circumference, body mass index, fasting plasma glucose, homeostasis model assessment of insulin resistance and HbA1c. Only body mass index was still inversely correlated with serum myonectin after multiple linear regression analysis. Conclusion Serum myonectin is correlated with obesity and increased after laparoscopic sleeve gastrectomy.

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Laparoscopic Sleeve Gastrectomy for Mildly Obese Patients (Body Mass Index of 30 <35 kg/m2): Operative Outcome and Short-Term Results

Journal of Obesity ◽

10.1155/2012/813650 ◽

2012 ◽

Vol 2012 ◽

pp. 1-5 ◽

Cited By ~ 10

Author(s):

Roger Noun ◽

Ghassan Chakhtoura ◽

Marwan Nasr ◽

Judith Skaff ◽

Naîm Choucair ◽

...

Keyword(s):

Body Mass Index ◽

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy ◽

Body Mass ◽

Operative Time ◽

Excess Weight ◽

Obese Patients ◽

Short Term ◽

Preoperative Body Mass Index ◽

Mild Obesity

Background. Data concerning laparoscopic sleeve gastrectomy (LSG) in mild obesity are under investigation.Aim/Objective. May 2010 to May 2012, 122 consecutive patients with preoperative body mass index (BMI) of33±2.5 kg/m2(range 30–34.9) undergoing LSG were studied. Mean age was33±10years (range 15–60), and 105 (86%) were women. Mean preoperative weight was91±9.7 kg (range 66–121), and preoperative excess weight was30±6.7 kg (range 19–43). Comorbidities were detected in 44 (36%) patients.Results. Mean operative time was58±15 min (range 40–95), and postoperative stay was1.8±0.19days (range 1.5–3). There were no admissions to intensive care unit and no deaths within 30 days of surgery. The rates of leaks and strictures were 0%, and of hemorrhage 1.6%. At 12 months, BMI decreased to24.7±2, and the percentage of excess weight loss (% EWL) reached 76.5%. None of the patients had a BMI below 20 kg/m2. Comorbidities resolved in 70.5% or improved in 29.5%. Patient satisfaction scoring (1–5) at least 1 year after was4.6±0.8for body image and4.4±0.6for food tolerance.Conclusion. LSG for mildly obese patients has proved to be technically relatively easy, safe, and benefic in the short term.

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Impact of laparoscopic sleeve gastrectomy on body mass index, ghrelin, insulin and lipid levels in 100 obese patients

Videosurgery and Other Miniinvasive Techniques ◽

10.5114/wiitm.2011.28979 ◽

2012 ◽

Vol 4 ◽

pp. 251-259 ◽

Cited By ~ 5

Author(s):

Hady Razak Hady ◽

Jacek Dadan ◽

Paweł Gołaszewski ◽

Kamil Safiejko

Keyword(s):

Body Mass Index ◽

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy ◽

Body Mass ◽

Obese Patients ◽

Lipid Levels

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Anesthesia for a 228-kg patient (body mass index, 90.6) undergoing laparoscopic sleeve gastrectomy

Journal of Anesthesia ◽

10.1007/s00540-011-1102-y ◽

2011 ◽

Vol 25 (2) ◽

pp. 278-281

Author(s):

Tomoki Nishiyama ◽

Yumiko Kohno ◽

Keiko Koishi

Keyword(s):

Body Mass Index ◽

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy ◽

Body Mass

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Laparoscopic sleeve gastrectomy for the super-super-obese (body mass index >60 kg/m2)

Surgery Today ◽

10.1007/s00595-007-3645-y ◽

2008 ◽

Vol 38 (5) ◽

pp. 399-403 ◽

Cited By ~ 77

Author(s):

Michel Gagner ◽

Andrew A. Gumbs ◽

Luca Milone ◽

Elliot Yung ◽

Liz Goldenberg ◽

...

Keyword(s):

Body Mass Index ◽

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy ◽

Body Mass ◽

Super Obese

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Comparison of the effects of laparoscopic sleeve gastrectomy in adults and adolescents

International Surgery Journal ◽

10.18203/2349-2902.isj20200504 ◽

2020 ◽

Vol 7 (3) ◽

pp. 630

Author(s):

Burcin Batman ◽

Hasan Altun

Keyword(s):

Body Mass Index ◽

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy ◽

Body Mass ◽

Insulin Level ◽

Benefit Evaluation ◽

Significant Difference ◽

Adolescents And Adults ◽

Treatment Of Obesity

Background: Obesity is an increasing problem worldwide regardless of age. Bariatric surgery is highly effective both in the treatment of obesity and in the improvement of obesity-related comorbidities. Laparoscopic sleeve gastrectomy is gaining popularity in both adolescents and the elderly.Methods: A total of 64 patients who underwent laparoscopic sleeve gastrectomy, aged under 19 and older 65 between March 2013 and December 2019 were enrolled in this retrospective study. Demographic characteristics were recorded in all patients.Results: Between March 2013 and December 2019, 64 patients who underwent laparoscopic sleeve gastrectomy were enrolled in this study. Fourty-five patients were smaller than 19 years old and 19 patients were older than 65 years old. After 1-year follow-up, there was a significant improvement in glucose, insulin level, excess weight loss and body mass index in both groups (p<0.001). There was no significant difference in insulin levels (p=0.2) and body mass index (p=0.94) between two groups.Conclusions: Careful patient selection after adequate risk versus benefit evaluation by an expert multidisciplinary team is essential. Laparoscopic sleeve gastrectomy is an effective treatment for obesity and its related comorbidities in both adolescents and adults.

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