Thyroid hormones modulate uric acid metabolism in patients with recent onset subclinical hypothyroidism by improving insulin sensitivity

2019 ◽  
Vol 15 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Giovambattista Desideri ◽  
Raffaella Bocale ◽  
Anna Maria D’Amore ◽  
Giulia Carnassale ◽  
Stefano Necozione ◽  
...  
Keyword(s):  
Uric Acid ◽  
Insulin Sensitivity ◽  
Thyroid Hormones ◽  
Subclinical Hypothyroidism ◽  
Acid Metabolism ◽  
Recent Onset

503-P: Inhibition of Glucose Transporter 9 Increases Serum Uric Acid Level but Attenuates Renal Albumin Excretion in Streptozotocin-Induced Diabetic Rats: A Role of Hepatic Uric Acid Metabolism

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 503-P
Author(s):  
CHUPING CHEN ◽  
JIANMIN RAN ◽  
RUYI ZHANG ◽  
GUANGSHU CHEN ◽  
PING ZHU ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Glucose Transporter ◽  
Acid Metabolism ◽  
Serum Uric Acid Level ◽  
Diabetic Rats ◽  
Glucose Transporter 9

scholarly journals STUDIES IN URIC ACID METABOLISM

1923 ◽  
Vol 55 (3) ◽  
pp. 373-384
Author(s):  
Howard B. Lewis ◽  
Ralph C. Corley
Keyword(s):  
Uric Acid ◽  
Acid Metabolism

scholarly journals RELATION OF URIC ACID METABOLISM TO RELEASE OF IRON FROM HEPATIC FERRITIN

1957 ◽  
Vol 227 (2) ◽  
pp. 653-668 ◽  
Author(s):  
Saul Green ◽  
Abraham Mazur
Keyword(s):  
Uric Acid ◽  
Acid Metabolism

scholarly journals STUDIES IN ENDOGENOUS URIC ACID METABOLISM

1914 ◽  
Vol 19 (4) ◽  
pp. 473-485
Author(s):  
G.W. Raiziss ◽  
H. Dubin ◽  
A.I. Ringer
Keyword(s):  
Uric Acid ◽  
Acid Metabolism

scholarly journals Serum uric acid and insulin sensitivity in adolescents and adults with and without type 1 diabetes

2014 ◽  
Vol 28 (3) ◽  
pp. 298-304 ◽  
Author(s):  
Petter Bjornstad ◽  
Janet K. Snell-Bergeon ◽  
Kimberly McFann ◽  
R. Paul Wadwa ◽  
Marian Rewers ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Uric Acid ◽  
Insulin Sensitivity ◽  
Serum Uric Acid ◽  
Adolescents And Adults

The effect of levothyroxine in comparison with placebo on serum osteocalcin levels in patients with subclinical hypothyroidism

2021 ◽  
Vol 16 ◽  
Author(s):  
Reihaneh Rezaee ◽  
Masoud Mohebbi ◽  
Mozhgan Afkhamizadeh ◽  
Mohammad Ali Yaghoubi ◽  
Mona Najaf Najafi ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Subclinical Hypothyroidism ◽  
Intervention Group ◽  
Serum Levels ◽  
Overt Hypothyroidism ◽  
Serum Osteocalcin ◽  
Significant Difference ◽  
Before And After ◽  
Metabolic Conditions ◽  
And Control

Background and Objective: Subclinical hypothyroidism can potentially develop to overt hypothyroidism. Thyroid hormones have substantial roles in metabolism and glucose homeostasis and thus are closely related to determinant factors of metabolic syndromes, such as obesity and insulin resistance. Osteocalcin is considered a predictor of metabolic conditions in thyroid diseases. This study aimed to investigate the effect of levothyroxine vs. placebo on serum osteocalcin levels in patients with subclinical hypothyroidism. Methods: This randomized clinical trial was performed on 30 patients with subclinical hypothyroidism who were referred to the endocrine clinics of Ghaem and Imam Reza hospitals in Mashhad, Iran. After giving informed consent, patients were randomly divided into intervention (50 µg/day levothyroxine for 2 months) and control (placebo) groups. Serum levels of osteocalcin, thyroid hormones, lipid profile, insulin, and fasting glucose, as well as other clinical and anthropometric data, were measured at baseline and at the end of the study. SPSS was used to analyze the data and P<0.05 was considered significant. Results: Mean age in the intervention and control groups was 35.07 ± 9.94 and 31.30 ± 4.30, respectively (P=0.20). There was no significant difference between osteocalcin levels before and after the intervention in either of the groups (P=0.54). TSH level was significantly decreased in the levothyroxine group after the intervention (P<0.01). T4 level was significantly increased in the intervention group (P=0.02). Conclusion: Levothyroxine had no significant effect on increasing the levels of serum osteocalcin in patients with subclinical hypothyroidism. We have registered the trial in the Iranian registry of clinical trials (IRCT) with the registration code IRCT20171129037677N1.

Disturbances of Uric Acid Metabolism

1983 ◽  
pp. 155-172
Author(s):  
Edwin Mejías ◽  
Manuel Martínez-Maldonado
Keyword(s):  
Uric Acid ◽  
Acid Metabolism

scholarly journals The Role of the Renal Dopaminergic and the Prostaglandin Systems in Renal Uric Acid Metabolism in Patients with Essential Hypertension

1991 ◽  
Vol 67 (11) ◽  
pp. 1271-1281
Author(s):  
Naotoshi SATOH ◽  
Kenjiro KIKUCHI ◽  
Tohru HASEGAWA ◽  
Hiroaki KOMURA ◽  
Shin-ichiro SUZUKI ◽  
...  
Keyword(s):  
Uric Acid ◽  
Essential Hypertension ◽  
Acid Metabolism

scholarly journals Effect of Fenofibrate on Uric Acid Metabolism and Urate Transporter 1

2010 ◽  
Vol 49 (2) ◽  
pp. 89-94 ◽  
Author(s):  
Daijiro Uetake ◽  
Iwao Ohno ◽  
Kimiyoshi Ichida ◽  
Yuichiro Yamaguchi ◽  
Hajime Saikawa ◽  
...  
Keyword(s):  
Uric Acid ◽  
Acid Metabolism ◽  
Urate Transporter
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