Pelvic organ prolapse and the lower urinary tract: The relationship of vaginal prolapse to stress urinary incontinence

This chapter summarizes the results of the Outcomes Following Vaginal Prolapse Repair and Midurethral Sling (OPUS) trial, in which women without stress urinary incontinence undergoing prolapse surgery were randomized to a midurethral sling or no concomitant midurethral sling. The OPUS trial found that women randomized to undergo prophylactic concomitant midurethral sling at the time of transvaginal repair for pelvic organ prolapse had lower rates of urinary incontinence at 3 and 12 months but also experienced higher rates of adverse events such as bladder perforation, major bleeding, and urinary tract infections.

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Sexual functions and quality of life of women over 50 years with urinary incontinence, lower urinary tract symptoms and/or pelvic organ prolapse

International Journal of Impotence Research ◽

10.1038/s41443-019-0219-7 ◽

2019 ◽

Vol 32 (5) ◽

pp. 535-543

Author(s):

Funda Gungor Ugurlucan ◽

Ipek Evruke ◽

Cenk Yasa ◽

Ozlem Dural ◽

Onay Yalcin

Keyword(s):

Quality Of Life ◽

Urinary Incontinence ◽

Urinary Tract ◽

Pelvic Organ Prolapse ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Pelvic Organ ◽

Urinary Tract Symptoms ◽

Lower Urinary

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The Influence of Vaginal Native Tissue Repair (VNTR) on Various Aspects of Quality of Life in Women with Symptomatic Pelvic Organ Prolapse—A Prospective Cohort Study

Journal of Clinical Medicine ◽

10.3390/jcm9061634 ◽

2020 ◽

Vol 9 (6) ◽

pp. 1634

Author(s):

Ewa Rechberger ◽

Katarzyna Skorupska ◽

Tomasz Rechberger ◽

Aleksandra Kołodyńska ◽

Paweł Miotła ◽

...

Keyword(s):

Quality Of Life ◽

Urinary Incontinence ◽

Urinary Tract ◽

Pelvic Organ Prolapse ◽

Tissue Repair ◽

Lower Urinary Tract ◽

Pelvic Organ ◽

Native Tissue Repair ◽

Lower Urinary

Pelvic organ prolapse (POP) and the associated functional disorders are a major epidemiological problem that compromises the quality of life (QoL). The aim of this study was to assess the impact of lower urinary tract symptoms (LUTS) related to POP and vaginal native tissue repair (VNTR) on QoL. Two hundred patients with symptomatic POP were stratified into four groups according to the dominant storage phase function disorders: Urgency; stress urinary incontinence (SUI); mixed urinary incontinence (MUI), and without clinically significant symptoms from lower urinary tract (LUT). They underwent VNTR from January 2018 to February 2019. After 12 months, the QoL was assessed by the Prolapse Quality of Life (P-QoL) and visual analogue scale (VAS) questionnaires. The data were analyzed with Statistica package version 12.0 (StatSoft, Krakow, Poland), using the Kalmogorow–Smirnoff, Shapiro–Wilk W and the one-way analysis of variance with post hoc Tukey tests. The results of P-QoL showed significant improvement (p < 0.05) in all the study groups in most domains assessed before surgery and 12 months after surgery. Significant improvements in all the symptoms assessed by the VAS scale results were found in groups Urgency and MUI. The LUTS questionnaire revealed significant improvement in all voiding and post voiding symptoms in these groups. VNTR effectively eliminated LUTS and significantly improved the patients’ QoL associated with POP.

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Urogynaecological Symptoms among Oncological Survivors and Impact of Oncological Treatment on Pelvic Floor Disorders and Lower Urinary Tract Symptoms. A Six-Month Follow-Up Study

Journal of Clinical Medicine ◽

10.3390/jcm9092804 ◽

2020 ◽

Vol 9 (9) ◽

pp. 2804

Author(s):

Alicja Ziętek-Strobl ◽

Konrad Futyma ◽

Izabela Kuna-Broniowska ◽

Małgorzata Wojtaś ◽

Tomasz Rechberger

Keyword(s):

Urinary Incontinence ◽

Urinary Tract ◽

Surgical Treatment ◽

Pelvic Organ Prolapse ◽

Lower Urinary Tract ◽

De Novo ◽

Pelvic Organ ◽

Urinary Tract Symptoms ◽

Lower Urinary

It has been widely underlined that both gynaecological malignancies and urogynaecological disorders are often associated with high stress and have a negative impact on the quality of life and psychological well-being of women affected. Knowledge of the pelvic anatomy is crucial in recommending and carrying out the least harmful although successful treatment. Subsequent chemoradiation may also induce or exaggerate troublesome symptoms. The aim of the study was to establish the frequency of urogynaecological symptoms (stress urinary incontinence, urgency, pelvic organ prolapse) and to assess the impact of surgical treatment and additional oncological therapy: pelvic radiation, chemoradiation, chemotherapy, on the prevalence of pelvic floor dysfunctions (PFD) and lower urinary tract symptoms (LUTS) in patients suffering from gynecological malignancies. The study group consisted of 160 women, diagnosed with gynaecological malignancy, who underwent surgical treatment and additional adjuvant treatment as necessary. To establish the QoL and prevalence of PFD Urinary Distress Inventory-6 (UDI-6), Incontinence Impact Questionnaire 7 (II-Q7), King’s Health Questionnaire (KHQ) and the SF-36 Questionnaire were used. Herein, 69 patients reported urinary incontinence (UI) and 67 reported symptoms of pelvic organ prolapse (POP). After the six months follow-up UI was found in 78 patients, 25 patients showed de novo symptoms, 65 patients reported POP and 10 patients demonstrated de novo POP. Our data show that urogynaecological symptoms are not correlated with the type of malignancy, but with the extensiveness of surgery.

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