Characterization of a Potential β-Lactamase Inhibitory Metabolite from a Marine Streptomyces sp. PM49 Active Against Multidrug-Resistant Pathogens

2015 ◽  
Vol 175 (8) ◽  
pp. 3696-3708 ◽  
Author(s):  
J. Shanthi ◽  
A. Senthil ◽  
V. Gopikrishnan ◽  
R. Balagurunathan
Keyword(s):  
Multidrug Resistant ◽  
Streptomyces Sp ◽  
Multidrug Resistant Pathogens ◽  
Marine Streptomyces

Isolation and characterization of novel α-amylase from marine Streptomyces sp. D1

2009 ◽  
Vol 58 (1-4) ◽  
pp. 17-23 ◽  
Author(s):  
Samrat Chakraborty ◽  
Abhijit Khopade ◽  
Chandrakant Kokare ◽  
Kakasaheb Mahadik ◽  
Balasaheb Chopade
Keyword(s):  
Streptomyces Sp ◽  
Isolation And Characterization ◽  
Marine Streptomyces

scholarly journals Cheminformatic Characterization of Natural Antimicrobial Products for the Development of New Lead Compounds

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3970
Author(s):  
Samson Olaitan Oselusi ◽  
Alan Christoffels ◽  
Samuel Ayodele Egieyeh
Keyword(s):  
Antimicrobial Resistance ◽  
Antimicrobial Agents ◽  
Multidrug Resistant ◽  
Potential Drug ◽  
Natural Antimicrobial ◽  
Drug Candidates ◽  
Lead Compounds ◽  
Multidrug Resistant Pathogens

The growing antimicrobial resistance (AMR) of pathogenic organisms to currently prescribed drugs has resulted in the failure to treat various infections caused by these superbugs. Therefore, to keep pace with the increasing drug resistance, there is a pressing need for novel antimicrobial agents, especially from non-conventional sources. Several natural products (NPs) have been shown to display promising in vitro activities against multidrug-resistant pathogens. Still, only a few of these compounds have been studied as prospective drug candidates. This may be due to the expensive and time-consuming process of conducting important studies on these compounds. The present review focuses on applying cheminformatics strategies to characterize, prioritize, and optimize NPs to develop new lead compounds against antimicrobial resistance pathogens. Moreover, case studies where these strategies have been used to identify potential drug candidates, including a few selected open-access tools commonly used for these studies, are briefly outlined.

Identification and characterization of a Streptomyces sp. isolate exhibiting activity against multidrug-resistant coagulase-negative Staphylococci

2011 ◽  
Vol 35 (8) ◽  
pp. 477-486 ◽  
Author(s):  
Saeed Sadigh-Eteghad ◽  
Alireza Dehnad ◽  
Dariush Shanebandi ◽  
Iraj Khalili ◽  
Nasser Razmarayii ◽  
...  
Keyword(s):  
Multidrug Resistant ◽  
Coagulase Negative Staphylococci ◽  
Streptomyces Sp ◽  
Identification And Characterization

Isolation of manumycin-type derivatives and genome characterization of a marine Streptomyces sp. C1-2

2021 ◽  
pp. 103812
Author(s):  
Sakkarn Chanadech ◽  
Duangkamol Ruen-ngam ◽  
Chakapong Intaraudom ◽  
Pattama Pittayakhajonwut ◽  
Sumet Chongruchiroj ◽  
...  
Keyword(s):  
Streptomyces Sp ◽  
Genome Characterization ◽  
Marine Streptomyces
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