Autoinflammatory Skin Disorders in Inflammatory Bowel Diseases, Pyoderma Gangrenosum and Sweet’s Syndrome: a Comprehensive Review and Disease Classification Criteria

2013 ◽  
Vol 45 (2) ◽  
pp. 202-210 ◽  
Author(s):  
Angelo V. Marzano ◽  
Rim S. Ishak ◽  
Simone Saibeni ◽  
Carlo Crosti ◽  
Pier Luigi Meroni ◽  
...  
Author(s):  
Abir Derbel ◽  
Chifa Damak ◽  
Mouna Snoussi ◽  
Faten Frikha ◽  
Slim Charfi ◽  
...  

Sweet’s syndrome (SS) is a rare disorder characterized by dermal infiltration by neutrophils. It has been reported in association with drugs, malignancies, infections, rheumatoid diseases, inflammatory bowel diseases. Its association with giant cell arteritis (GCA) hasn’t been reported to our knowledge. The diagnosis of GCA was based on inflammatory biological syndrome with aortitis with negative infectious investigations. Herein, we present an unusual case of SS associated with GCA treated with steroids with good outcomes.


Medicine ◽  
2008 ◽  
Vol 87 (5) ◽  
pp. 281-293 ◽  
Author(s):  
David Farhi ◽  
Jacques Cosnes ◽  
Nada Zizi ◽  
Olivier Chosidow ◽  
Philippe Seksik ◽  
...  

2019 ◽  
Vol 1 (1) ◽  
pp. 7-9
Author(s):  
Klaudia Dopytalska ◽  
Piotr Sobolewski ◽  
Marek Roszkiewicz ◽  
Agata Mikucka-Wituszyńska ◽  
Elżbieta Szymańska ◽  
...  

Pyoderma gangrenosum (PG) is a rare, neutrophilic dermatosis with extracutaneous manifestations and associated systemic disorders, including inflammatory bowel diseases, arthritis and haematological malignancies. The pathogenesis of PG is still not fully understood. The cutaneous lesions are often polymorphic and include papules, nodules, sterile pustules with erythematous induration, which quickly evolve into necrotic painful ulcerations. PG can also affect lungs, spleen, liver, pancreas, kidneys, bones and eyes. The treatment of PG is long and challenging and involves the use of sytemic corticoteroids, immunosupressive drugs and biological therapies with concomitant pain management and wound care.


2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Sarah Abi Doumeth ◽  
Ossama Abbas ◽  
Jana G Hashash

Abstract Pyostomatitis vegetans (PV) is a rare inflammatory stomatitis often associated with inflammatory bowel diseases (IBD). Treatment of PV depends on the presence of coexisting IBD. To date, there have been no reports on the use of ustekinumab for PV. There have been recent cases on the use of ustekinumab for treatment of pyoderma gangrenosum and uveitis. We report the case of a 26-year-old female with moderately severe Crohn’s disease (CD) and PV who was successfully treated with ustekinumab monotherapy. Since initiation of ustekinumab, she has been in clinical and biochemical remission from a CD and PV standpoint for the last 12 months.


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