Long-term management of lenvatinib-treated thyroid cancer patients: a real-life experience at a single institution

Endocrine ◽  
2021 ◽  
Author(s):  
Tommaso Porcelli ◽  
Cristina Luongo ◽  
Francesca Sessa ◽  
Michele Klain ◽  
Stefania Masone ◽  
...  
Oncology ◽  
2019 ◽  
Vol 97 (4) ◽  
pp. 206-210 ◽  
Author(s):  
Nerina Denaro ◽  
Adele Latina ◽  
Flora Cesario ◽  
Fabio Bramardi ◽  
Lauro Corrado ◽  
...  

2021 ◽  
Vol 39 (S2) ◽  
Author(s):  
E. M. Gonzalez Barca ◽  
J. M. Sancho ◽  
J. Rovira ◽  
N. Kelleher ◽  
M. Kara ◽  
...  

2021 ◽  
Vol 10 (9) ◽  
pp. 1852
Author(s):  
Gry Assam Taarnhøj ◽  
Henriette Lindberg ◽  
Christoffer Johansen ◽  
Helle Pappot

Patients with urothelial cell carcinoma (UCC) often have comorbidities, which cause trouble for the completion of oncological treatment, and little is known about their quality of life (QoL). The aim of the present study was to obtain and describe patient-reported outcomes (PRO) and QoL data from UCC patients in the treatment for locally advanced muscle-invasive or metastatic UCC. A total of 79 patients with UCC completed four questionnaires (EORTC QLQ-C30, QLQ-BLM30, HADS, and select PRO-CTCAE™ questions) once weekly during their treatment. From those, 26 patients (33%) underwent neoadjuvant treatment for local disease while 53 patients (67%) were treated for metastatic disease. Of all patients, 54% did not complete the planned treatment due to progression, nephrotoxicity, death, or intolerable symptoms during treatment. The five most prevalent PRO-CTCAE grade ≥ 2 symptoms were frequent urination (37%), fatigue (35%), pain (31%), dry mouth (23%), and swelling of the arms or legs (23%). The baseline mean overall QoL was 61 (±SD 24) for all patients (neoadjuvant (73, ±SD 19) and metastatic (54, ±SD 24)) and remained stable over the course of treatment for both groups. A stable overall QoL was observed for the patients in this study. More than half of the patients did not, however, complete the planned treatment. Further supportive care is warranted for bladder cancer patients.


2007 ◽  
Vol 67 (5) ◽  
pp. 717-719 ◽  
Author(s):  
L C Coates ◽  
L S Cawkwell ◽  
N W F Ng ◽  
A N Bennett ◽  
D J Bryer ◽  
...  

Author(s):  
David Isenberg ◽  
Angela Zink

Double-blind controlled trials undertaken over the past two decades have established the short-term effectiveness and side-effect profile of biologic drugs for patients with rheumatoid arthritis and related diseases. However, the development of biologics registers to capture ’real-life experience’ and explore long-term effectiveness and complications is equally important. In this chapter, we demonstrate how these registers have identified long-term joint benefits, a reduction in cardiovascular mortality, reassurance concerning fears about cancer development, and a balanced view of the risk of infection.


2020 ◽  
Vol 55 (6) ◽  
pp. 718-724
Author(s):  
Fredrik Åberg ◽  
John Berntsson ◽  
Gustaf Herlenius ◽  
Maria Castedal ◽  
William Bennet

2019 ◽  
Vol 13 (Supplement_1) ◽  
pp. S393-S394
Author(s):  
M Iborra ◽  
N García-Morales ◽  
S Rubio ◽  
O Nantes Castillejo ◽  
F Bertoletti ◽  
...  

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