scholarly journals Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain Injury

2019 ◽  
Vol 67 (4) ◽  
pp. 613-621 ◽  
Author(s):  
V. Rubovitch ◽  
A. Pharayra ◽  
M. Har-Even ◽  
O. Dvir ◽  
M. P. Mattson ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Mouse Model ◽  
Energy Restriction ◽  
Dietary Energy ◽  
Dietary Energy Restriction

scholarly journals Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury

2016 ◽  
Vol 36 (43) ◽  
pp. 11084-11096 ◽  
Author(s):  
W. Yu ◽  
R. Parakramaweera ◽  
S. Teng ◽  
M. Gowda ◽  
Y. Sharad ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Potassium Channels ◽  
Mouse Model

NEUROPSYCHOLOGICAL CHANGES IN PATIENTS WITH A CONSEQUENCE OF TRAUMATIC BRAIN INJURY

2020 ◽  
Vol 3 (1) ◽  
pp. 44-46
Author(s):  
Istatillo Shodjalilov ◽  
◽  
Saoda Igamova ◽  
Aziza Djurabekova
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Neuropsychological Testing ◽  
Anxiety And Depression ◽  
Psychopathological Symptoms ◽  
Neuropsychological Changes ◽  
The Relationship

The incidence of cognitive impairment in TBI is high, depending on the severity. At the same time, psychopathological symptoms in the form of asthenia, increased anxiety and depression are encountered among patients with TBI. The work studied the relationship between cognitive and psychopathological symptoms in patients with TBI using neuropsychological testing on scales.

scholarly journals Acute treatment with TrkB agonist LM22A-4 confers neuroprotection and preserves myelin integrity in a mouse model of pediatric traumatic brain injury

2021 ◽  
Vol 339 ◽  
pp. 113652
Author(s):  
Jessica L. Fletcher ◽  
Larissa K. Dill ◽  
Rhiannon J. Wood ◽  
Sharon Wang ◽  
Kate Robertson ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mouse Model ◽  
Acute Treatment ◽  
Pediatric Traumatic Brain Injury

scholarly journals Peroxynitrite-Mediated Protein Nitration and Lipid Peroxidation in a Mouse Model of Traumatic Brain Injury

2004 ◽  
Vol 21 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Edward D. Hall ◽  
Megan R. Detloff ◽  
Kjell Johnson ◽  
Nancy C. Kupina
Keyword(s):  
Traumatic Brain Injury ◽  
Lipid Peroxidation ◽  
Brain Injury ◽  
Mouse Model ◽  
Protein Nitration

Comparison of Cognitive Impairment Associated With Major Depression Following Stroke Versus Traumatic Brain Injury

2002 ◽  
Vol 43 (4) ◽  
pp. 295-301 ◽  
Author(s):  
Amane Tateno ◽  
Yuichi Murata ◽  
Robert G. Robinson
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Major Depression

scholarly journals Cardiometabolic and reproductive benefits of early dietary energy restriction and voluntary exercise in an obese PCOS-prone rodent model

2015 ◽  
Vol 226 (3) ◽  
pp. 193-206 ◽  
Author(s):  
Abdoulaye Diane ◽  
Maria Kupreeva ◽  
Faye Borthwick ◽  
Spencer D Proctor ◽  
W David Pierce ◽  
...  
Keyword(s):  
Cardiometabolic Risk ◽  
Energy Restriction ◽  
Rodent Model ◽  
Voluntary Exercise ◽  
Chow Diet ◽  
Adult Women ◽  
Dietary Energy ◽  
Lean Control ◽  
Dietary Energy Restriction ◽  
Reproductive Indices

Polycystic ovary syndrome (PCOS) is one of the most common endocrine-metabolic disorders in women of reproductive age characterized by ovulatory dysfunction, hyperandrogenism and cardiometabolic risk. The overweight-obese PCOS phenotype appears to have exacerbated reproductive dysfunction and cardiometabolic risk. In overweight-obese adult women with PCOS, exercise and energy restricted diets have shown limited and inconsistent effects on both cardiometabolic indices and reproductive outcomes. We hypothesized that an early lifestyle intervention involving exercise and dietary energy restriction to prevent or reduce the propensity for adiposity would modulate reproductive indices and cardiometabolic risk in an obese PCOS-prone rodent model. Weanling obese PCOS-prone and Lean-Control JCR:LA-cp rodents were given a chow dietad libitumor an energy-restricted diet combined with or without voluntary exercise (4 h/day) for 8 weeks. Dietary energy restriction and exercise lowered total body weight gain and body fat mass by 30% compared to free-fed sedentary or exercising obese PCOS-prone animals (P<0.01). Energy restriction induced an increase in exercise intensity compared to free-feeding plus exercise conditions. Energy restriction and exercise decreased fasting plasma triglycerides and apoB48 concentrations in obese PCOS-prone animals compared to free-fed and exercise or sedentary groups. The energy restriction and exercise combination in obese PCOS-prone animals significantly increased plasma sex-hormone binding globulin, hypothalamic cocaine-and amphetamine-regulated transcript (CART) and Kisspeptin mRNA expression to levels of the Lean-Control group, and this was further associated with improvements in estrous cyclicity. The combination of exercise and dietary energy restriction when initiated in early life exerts beneficial effects on cardiometabolic and reproductive indices in an obese PCOS-prone rodent model, and this may be associated with normalization of the hypothalamic neuropeptides, Kisspeptin and CART.

scholarly journals Does severe dietary energy restriction increase binge eating in overweight or obese individuals? A systematic review

2015 ◽  
Vol 16 (8) ◽  
pp. 652-665 ◽  
Author(s):  
F. Q. da Luz ◽  
P. Hay ◽  
A. A. Gibson ◽  
S. W. Touyz ◽  
J. M. Swinbourne ◽  
...  
Keyword(s):  
Systematic Review ◽  
Binge Eating ◽  
Energy Restriction ◽  
Dietary Energy ◽  
Dietary Energy Restriction

The Neuroprotective Effect of Salubrinal in a Mouse Model of Traumatic Brain Injury

2015 ◽  
Vol 17 (1) ◽  
pp. 58-70 ◽  
Author(s):  
Vardit Rubovitch ◽  
Shani Barak ◽  
Lital Rachmany ◽  
Renana Baratz Goldstein ◽  
Yael Zilberstein ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mouse Model ◽  
Neuroprotective Effect
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