Elevation of DNA Methylation in the Promoter Regions of the Brain-Derived Neurotrophic Factor Gene is Associated with Heroin Addiction

2021 ◽  
Author(s):  
Yifan Xiao ◽  
Yongsheng Zhu ◽  
Yunxiao Li
Keyword(s):  
Dna Methylation ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Heroin Addiction ◽  
Promoter Regions ◽  
Factor Gene ◽  
The Brain

Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorder

2010 ◽  
Vol 125 (1-3) ◽  
pp. 345-349 ◽  
Author(s):  
Georgina M. Hosang ◽  
Rudolf Uher ◽  
Robert Keers ◽  
Sarah Cohen-Woods ◽  
Ian Craig ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Life Events ◽  
Neurotrophic Factor ◽  
Stressful Life Events ◽  
Brain Derived Neurotrophic Factor ◽  
Stressful Life ◽  
Factor Gene ◽  
The Brain

Prophylactic Lithium Response and Polymorphism of the Brain-Derived Neurotrophic Factor Gene

2005 ◽  
Vol 38 (4) ◽  
pp. 166-170 ◽  
Author(s):  
J. K. Rybakowski ◽  
A. Suwalska ◽  
M. Skibinska ◽  
A. Szczepankiewicz ◽  
A. Leszczynska-Rodziewicz ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Factor Gene ◽  
Lithium Response ◽  
The Brain

Observed parenting behaviors interact with a polymorphism of the brain-derived neurotrophic factor gene to predict the emergence of oppositional defiant and callous–unemotional behaviors at age 3 years

2013 ◽  
Vol 25 (4pt1) ◽  
pp. 903-917 ◽  
Author(s):  
Michael T. Willoughby ◽  
Roger Mills-Koonce ◽  
Cathi B. Propper ◽  
Daniel A. Waschbusch
Keyword(s):  
Child Health ◽  
Disruptive Behavior ◽  
Neurotrophic Factor ◽  
Parenting Behaviors ◽  
Brain Derived Neurotrophic Factor ◽  
Factor Gene ◽  
Callous Unemotional ◽  
Oppositional Defiant ◽  
Health And Development ◽  
The Brain

AbstractUsing the Durham Child Health and Development Study, this study (N = 171) tested whether observed parenting behaviors in infancy (6 and 12 months) and toddlerhood/preschool (24 and 36 months) interacted with a child polymorphism of the brain-derived neurotrophic factor gene to predict oppositional defiant disorder (ODD) and callous–unemotional (CU) behaviors at age 3 years. Child genotype interacted with observed harsh and intrusive (but not sensitive) parenting to predict ODD and CU behaviors. Harsh–intrusive parenting was more strongly associated with ODD and CU for children with a methionine allele of the brain-derived neurotrophic factor gene. CU behaviors were uniquely predicted by harsh–intrusive parenting in infancy, whereas ODD behaviors were predicted by harsh–intrusive parenting in both infancy and toddlerhood/preschool. The results are discussed from the perspective of the contributions of caregiving behaviors as contributing to distinct aspects of early onset disruptive behavior.

scholarly journals Haploinsufficiency of the brain-derived neurotrophic factor gene is associated with reduced pain sensitivity

Pain ◽  
2019 ◽  
Vol 160 (5) ◽  
pp. 1070-1081 ◽  
Author(s):  
Matthew R. Sapio ◽  
Michael J. Iadarola ◽  
Danielle M. LaPaglia ◽  
Tanya Lehky ◽  
Audrey E. Thurm ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Pain Sensitivity ◽  
Brain Derived Neurotrophic Factor ◽  
Factor Gene ◽  
The Brain
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