The prostate cancer-up-regulated myc-associated zinc-finger protein (MAZ) modulates proliferation and metastasis through reciprocal regulation of androgen receptor

2013 ◽  
Vol 30 (2) ◽  
Author(s):  
Li Jiao ◽  
Yun Li ◽  
Dan Shen ◽  
Chuanliang Xu ◽  
Linhui Wang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Reciprocal Regulation ◽  
Finger Protein ◽  
Proliferation And Metastasis

scholarly journals Downregulation of zinc finger protein 132 in prostate cancer is associated with aberrant promoter hypermethylation and poor prognosis

2011 ◽  
Vol 130 (4) ◽  
pp. 885-895 ◽  
Author(s):  
Mette Opstrup Abildgaard ◽  
Michael Borre ◽  
Martin Mørck Mortensen ◽  
Benedicte P. Ulhøi ◽  
Niels Tørring ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Zinc Finger ◽  
Poor Prognosis ◽  
Zinc Finger Protein ◽  
Promoter Hypermethylation ◽  
Finger Protein

Human endogenous retrovirus protein Rec interacts with the testicular zinc-finger protein and androgen receptor

2010 ◽  
Vol 91 (6) ◽  
pp. 1494-1502 ◽  
Author(s):  
S. Kaufmann ◽  
M. Sauter ◽  
M. Schmitt ◽  
B. Baumert ◽  
B. Best ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Endogenous Retrovirus ◽  
Human Endogenous Retrovirus ◽  
Finger Protein

A zinc finger protein TZF is a novel corepressor of androgen receptor

2005 ◽  
Vol 331 (4) ◽  
pp. 1025-1031 ◽  
Author(s):  
Masamichi Ishizuka ◽  
Hisaya Kawate ◽  
Ryoichi Takayanagi ◽  
Hirotaka Ohshima ◽  
Rong-Hua Tao ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Finger Protein

scholarly journals Localization of murine X and autosomal sequences homologous to the human Y located testis-determining region.

Genetics ◽  
1989 ◽  
Vol 121 (4) ◽  
pp. 803-809
Author(s):  
M Mitchell ◽  
D Simon ◽  
N Affara ◽  
M Ferguson-Smith ◽  
P Avner ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Autosomal Locus ◽  
Testicular Feminization ◽  
Human Sequence ◽  
Finger Protein ◽  
Receptor Locus ◽  
Determining Factor ◽  
Human Y Chromosome

Abstract Recently a candidate gene for the primary testis-determining factor (TDF) encoding a zinc finger protein (ZFY) has been cloned from the human Y chromosome. A highly homologous X-linked copy has also been identified. Using this human sequence it is possible to identify two Y loci, an X and an autosomal locus in the mouse (Zfy-1, Zfy-2, Zfx and Zfa, respectively). Suprisingly ZFY is more homologous to the mouse X and autosomal sequences than it is to either of the Y-linked loci. Both Zfy-1 and Zfy-2 are present in the Sxr region of the Y but Zfy-2 is absent in the Sxr deletion variant Sxrb (or Sxr") suggesting it is not necessary for male determination. Extensive backcross analyses map Zfa to mouse chromosome 10 and Zfx to a 5-cM interval between anonymous X probe MDXS120 and the tabby locus (Ta). We also show that the mouse androgen receptor locus (m-AR) believed to underlie the testicular feminization mutation (Tfm) shows complete linkage to Zfx. Comparative mapping indicates that in man these genes lie in separate conserved DNA segments.

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