scholarly journals Effect of cigarette smoking on paraoxonase 1 activity according to PON1 L55M and PON1 Q192R gene polymorphisms

2011 ◽  
Vol 17 (4) ◽  
pp. 316-321 ◽  
Author(s):  
Dhouha Haj Mouhamed ◽  
Asma Ezzaher ◽  
Anwar Mechri ◽  
Fadoua Neffati ◽  
Asma Omezzine ◽  
...  
2015 ◽  
Vol 241 (1) ◽  
pp. e173-e174
Author(s):  
N. Decharatchakul ◽  
C. Settasatian ◽  
N. Settasatian ◽  
P. Yongsakulchai ◽  
I. Sarutipaiboon ◽  
...  

Author(s):  
Göknur Kalkan ◽  
Havva Y. Seçkin ◽  
İsmail Benli ◽  
Ali Akbaş ◽  
Ömer Ateş ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Joanna Iwanicka ◽  
Tomasz Iwanicki ◽  
Paweł Niemiec ◽  
Tomasz Nowak ◽  
Jolanta Krauze ◽  
...  

Paraoxonase-1 (PON1) is the antioxidant marker of high-density lipoproteins protecting against atherosclerosis and coronary artery disease (CAD) phenotype. The purpose of the present study was to determine whether thePON1gene rs854560 polymorphism (163T>A) is associated with CAD in Polish population. rs854560 was genotyped in 494 subjects: 248 patients with premature CAD and 246 blood donors as a control. We found that the risk of CAD was significantly higher in TT homozygotes than in A allele carriers (OR = 1.87,p=0.041). The synergistic effect between the TT genotype and cigarette smoking was observed (SIM = 9.81; SI = 14.70). The relative increase in risk from interaction between factors was over 37 (RERI = 36.13). ThePON1polymorphism did not modulate the risk of CAD in response to exposure to other traditional risk factors. In conclusion, the rs854560 polymorphism may modulate the risk of CAD in response to cigarette smoking in Polish population. Carriers of TT genotype seem to be particularly at risk of CAD, when exposed to cigarette smoking.


2008 ◽  
Vol 123 (4) ◽  
pp. 359-369 ◽  
Author(s):  
Hui-Ju Tsai ◽  
Xin Liu ◽  
Karen Mestan ◽  
Yunxian Yu ◽  
Shanchun Zhang ◽  
...  

Medicine ◽  
2016 ◽  
Vol 95 (44) ◽  
pp. e5298 ◽  
Author(s):  
Yazmín Hernández-Díaz ◽  
Carlos Alfonso Tovilla-Zárate ◽  
Isela Esther Juárez-Rojop ◽  
Thelma Beatriz González-Castro ◽  
Candelario Rodríguez-Pérez ◽  
...  

2006 ◽  
Vol 47 (9) ◽  
pp. 699-706 ◽  
Author(s):  
Héctor C. Cataño ◽  
Jayme L. Cueva ◽  
Anthony M. Cardenas ◽  
VÍctor Izaguirre ◽  
Amparo I. Zavaleta ◽  
...  

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