scholarly journals Numerical Investigations on Alternate Droplet Formation in Microfluidic Devices

2021 ◽  
Vol 33 (6) ◽  
Author(s):  
Sripada Raja ◽  
M. N. Satyanarayan ◽  
G. Umesh ◽  
Gopalkrishna Hegde
Keyword(s):  
Microfluidic Devices ◽  
Droplet Formation ◽  
Numerical Investigations

Correlations of droplet formation in T-junction microfluidic devices: from squeezing to dripping

2008 ◽  
Vol 5 (6) ◽  
pp. 711-717 ◽  
Author(s):  
J. H. Xu ◽  
S. W. Li ◽  
J. Tan ◽  
G. S. Luo
Keyword(s):  
Microfluidic Devices ◽  
Droplet Formation

scholarly journals Three-Dimensional Printed Devices in Droplet Microfluidics

Micromachines ◽  
2019 ◽  
Vol 10 (11) ◽  
pp. 754 ◽  
Author(s):  
Jia Ming Zhang ◽  
Qinglei Ji ◽  
Huiling Duan
Keyword(s):  
Three Dimensional ◽  
Microfluidic Devices ◽  
Droplet Formation ◽  
Droplet Microfluidics ◽  
Current Development ◽  
Three Dimensional Printing ◽  
The Cost ◽  
Novel Structures ◽  
Dimensional Printing

Droplet microfluidics has become the most promising subcategory of microfluidics since it contributes numerous applications to diverse fields. However, fabrication of microfluidic devices for droplet formation, manipulation and applications is usually complicated and expensive. Three-dimensional printing (3DP) provides an exciting alternative to conventional techniques by simplifying the process and reducing the cost of fabrication. Complex and novel structures can be achieved via 3DP in a simple and rapid manner, enabling droplet microfluidics accessible to more extensive users. In this article, we review and discuss current development, opportunities and challenges of applications of 3DP to droplet microfluidics.

The dynamic mass transfer of surfactants upon droplet formation in coaxial microfluidic devices

2015 ◽  
Vol 132 ◽  
pp. 1-8 ◽  
Author(s):  
Yang Chen ◽  
Guo-Tao Liu ◽  
Jian-Hong Xu ◽  
Guang-Sheng Luo
Keyword(s):  
Mass Transfer ◽  
Microfluidic Devices ◽  
Droplet Formation ◽  
Dynamic Mass

The Dynamic Effects of Surfactants on Droplet Formation in Coaxial Microfluidic Devices

Langmuir ◽  
2012 ◽  
Vol 28 (25) ◽  
pp. 9250-9258 ◽  
Author(s):  
J. H. Xu ◽  
P. F. Dong ◽  
H. Zhao ◽  
C. P. Tostado ◽  
G. S. Luo
Keyword(s):  
Microfluidic Devices ◽  
Droplet Formation ◽  
Dynamic Effects

Numerical simulation of droplet formation in different microfluidic devices

2020 ◽  
Vol 234 (19) ◽  
pp. 3776-3788
Author(s):  
Pooria Hadikhani ◽  
Sahand Majidi ◽  
Asghar Afshari
Keyword(s):  
Microfluidic Devices ◽  
Droplet Formation ◽  
Continuous Phase ◽  
Strong Impact ◽  
Generation Process ◽  
Flow Solver ◽  
Computational Performance ◽  
Flow Features ◽  
Multi Phase Flow ◽  
Numerical Solver

This study aims to assess the droplet formation process in microfluidic devices using an all Mach-number multi-phase flow solver. Harten-Lax-van Leer-Contact (HLLC) Riemann solver is implemented for solving the discretized equations while Tangent of Hyperbola for INterface Capturing (THINC) method is applied to reduce the excessive diffusion of the method at the interface. The multi-block strategy is implemented in the flow solver to improve its capability of simulating flows in more complicated, multi-port droplet formation geometries. First, the computational performance of the numerical solver is validated through simulating the benchmark Rayleigh-Taylor instability problem and the droplet formation in a planar flow-focusing geometry. The comparison of numerical results with available analytical/experimental data indicates a precise prediction of flow features. Then, the droplet generation process in coflowing devices with Newtonian liquid is numerically studied. Finally, the shear-thinning effects of the dispersed and continuous phase on the drop formation characteristics are investigated. It is shown that deviation of the continuous phase from Newtonian behavior has a strong impact on droplet size, speed, and generation rate. On the other hand, assuming the dispersed phase as non-Newtonian does not strongly affect the aforementioned properties of the droplet formation regime.

scholarly journals An asymmetric flow-focusing droplet generator promotes rapid mixing of reagents

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
K. I. Belousov ◽  
N. A. Filatov ◽  
I. V. Kukhtevich ◽  
V. Kantsler ◽  
A. A. Evstrapov ◽  
...  
Keyword(s):  
Numerical Simulations ◽  
Microfluidic Devices ◽  
Droplet Formation ◽  
Droplet Microfluidics ◽  
Mixing Efficiency ◽  
Generation Process ◽  
Droplet Generator ◽  
Flow Focusing ◽  
Asymmetric Flow ◽  
Rapid Mixing

AbstractNowadays droplet microfluidics is widely used to perform high throughput assays and for the synthesis of micro- and nanoparticles. These applications usually require packaging several reagents into droplets and their mixing to start a biochemical reaction. For rapid mixing microfluidic devices usually require additional functional elements that make their designs more complex. Here we perform a series of 2D numerical simulations, followed by experimental studies, and introduce a novel asymmetric flow-focusing droplet generator, which enhances mixing during droplet formation due to a 2D or 3D asymmetric vortex, located in the droplet formation area of the microfluidic device. Our results suggest that 2D numerical simulations can be used for qualitative analysis of two-phase flows and droplet generation process in quasi-two-dimensional devices, while the relative simplicity of such simulations allows them to be easily applied to fairly complicated microfluidic geometries. Mixing inside droplets formed in the asymmetric generator occurs up to six times faster than in a conventional symmetric one. The best mixing efficiency is achieved in a specific range of droplet volumes, which can be changed by scaling the geometry of the device. Thus, the droplet generator suggested here can significantly simplify designs of microfluidic devices because it enables both the droplet formation and fast mixing of the reagents within droplets. Moreover, it can be used to precisely estimate reaction kinetics.

Effects of fluid-fluid interfacial elasticity on droplet formation in microfluidic devices

AIChE Journal ◽  
2010 ◽  
Vol 57 (7) ◽  
pp. 1669-1677 ◽  
Author(s):  
Chun-Xia Zhao ◽  
Erik Miller ◽  
Justin J. Cooper-White ◽  
Anton P. J. Middelberg
Keyword(s):  
Microfluidic Devices ◽  
Droplet Formation
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