Transcriptome Analysis in Patients with Progressive Coronary Artery Disease: Identification of Differential Gene Expression in Peripheral Blood

2012 ◽  
Vol 6 (1) ◽  
pp. 81-93 ◽  
Author(s):  
Thomas G. Nührenberg ◽  
Nicole Langwieser ◽  
Harald Binder ◽  
Thorsten Kurz ◽  
Christian Stratz ◽  
...  
Keyword(s):  
Gene Expression ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Differential Gene Expression ◽  
Transcriptome Analysis ◽  
Peripheral Blood ◽  
Disease Identification ◽  
Differential Gene ◽  
Artery Disease

scholarly journals Peripheral blood gene expression profile of atherosclerotic coronary artery disease in patients of different ethnicity in Malaysia

2012 ◽  
Vol 60 (3) ◽  
pp. 192-203 ◽  
Author(s):  
Mohd Hafiz Ngoo Abdullah ◽  
Zulhabri Othman ◽  
Hamdan Mohd Noor ◽  
Siti Suri Arshad ◽  
Ahmad Khairuddin Mohd Yusof ◽  
...  
Keyword(s):  
Gene Expression ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Peripheral Blood ◽  
Blood Gene Expression ◽  
Peripheral Blood Gene Expression ◽  
Artery Disease

scholarly journals Gene Expression Patterns in Peripheral Blood Correlate with the Extent of Coronary Artery Disease

PLoS ONE ◽  
2009 ◽  
Vol 4 (9) ◽  
pp. e7037 ◽  
Author(s):  
Peter R. Sinnaeve ◽  
Mark P. Donahue ◽  
Peter Grass ◽  
David Seo ◽  
Jacky Vonderscher ◽  
...  
Keyword(s):  
Gene Expression ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Blood ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Artery Disease

scholarly journals The p66shc Gene Expression in Peripheral Blood Monocytes Is Increased in Patients With Coronary Artery Disease

2010 ◽  
Vol 33 (9) ◽  
pp. 548-552 ◽  
Author(s):  
Yoshihiro Noda ◽  
Sho-ichi Yamagishi ◽  
Takanori Matsui ◽  
So Ueda ◽  
Shin-ichiro Ueda ◽  
...  
Keyword(s):  
Gene Expression ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Blood ◽  
Blood Monocytes ◽  
Peripheral Blood Monocytes ◽  
Artery Disease

Identification of endogenous control genes for gene expression studies in peripheral blood of patients with coronary artery disease

2013 ◽  
Vol 47 (2) ◽  
pp. 192-196 ◽  
Author(s):  
Siew Wai Fong ◽  
Suhairi Ibrahim ◽  
Mohd Sapawi Mohamed ◽  
Ling Ling Few ◽  
Wei Cun See Too ◽  
...  
Keyword(s):  
Gene Expression ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Blood ◽  
Endogenous Control ◽  
Expression Studies ◽  
Gene Expression Studies ◽  
Artery Disease

scholarly journals High retinoic acid receptor-related orphan receptor A gene expression in peripheral blood leukocytes may be related to acute myocardial infarction

2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110196
Author(s):  
Heyu Meng ◽  
Jianjun Ruan ◽  
Xiaomin Tian ◽  
Lihong Li ◽  
Weiwei Chen ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Acute Myocardial Infarction ◽  
Coronary Artery ◽  
Peripheral Blood ◽  
Retinoic Acid Receptor ◽  
Stable Coronary Artery Disease ◽  
Orphan Receptor ◽  
Blood Leukocytes ◽  
Artery Disease

Objective This study aimed to investigate whether differential expression of the retinoic acid receptor-related orphan receptor A ( RORA) gene is related to occurrence of acute myocardial infarction (AMI). Methods This was a retrospective study. White blood cells of 93 patients with acute myocardial infarction and 74 patients with stable coronary artery disease were collected. Reverse transcription quantitative polymerase chain reaction and western blotting were used to measure RORA mRNA and protein expression, respectively. Results RORA mRNA expression levels in peripheral blood leukocytes in patients with AMI were 1.57 times higher than those in patients with stable coronary artery disease. Protein RORA levels in peripheral blood of patients with AMI were increased. Binary logistic regression analysis showed that high expression of RORA was an independent risk factor for AMI, and it increased the risk of AMI by 2.990 times. Conclusion RORA expression levels in patients with AMI is significantly higher than that in patients with stable coronary artery disease. High expression of RORA is related to AMI and it may be an independent risk factor for AMI.

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