scholarly journals Development of a Swine Model of Left Bundle Branch Block for Experimental Studies of Cardiac Resynchronization Therapy

2013 ◽  
Vol 6 (4) ◽  
pp. 616-622 ◽  
Author(s):  
Montserrat Rigol ◽  
Núria Solanes ◽  
Juan Fernandez-Armenta ◽  
Etelvino Silva ◽  
Adelina Doltra ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Bundle Branch Block ◽  
Experimental Studies ◽  
Cardiac Resynchronization ◽  
Swine Model ◽  
Resynchronization Therapy ◽  
Bundle Branch Block

scholarly journals The definition of left bundle branch block influences the response to cardiac resynchronization therapy

2018 ◽  
Vol 269 ◽  
pp. 165-169 ◽  
Author(s):  
Maria Luce Caputo ◽  
Antonius van Stipdonk ◽  
Annekatrin Illner ◽  
Gabriele D'Ambrosio ◽  
François Regoli ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Bundle Branch Block ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Bundle Branch Block ◽  
Definition Of

scholarly journals True complete left bundle branch block morphology strongly predicts good response to cardiac resynchronization therapy

EP Europace ◽  
2013 ◽  
Vol 15 (10) ◽  
pp. 1499-1506 ◽  
Author(s):  
Yun Tian ◽  
Ping Zhang ◽  
Xuebin Li ◽  
Ying Gao ◽  
Tiangang Zhu ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Bundle Branch Block ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Bundle Branch Block

scholarly journals Greater response to cardiac resynchronization therapy in patients with true complete left bundle branch block: a PREDICT substudy

EP Europace ◽  
2011 ◽  
Vol 14 (5) ◽  
pp. 690-695 ◽  
Author(s):  
M. J. Perrin ◽  
M. S. Green ◽  
C. J. Redpath ◽  
P. B. Nery ◽  
A. Keren ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Bundle Branch Block ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Bundle Branch Block

scholarly journals Relationship between left bundle branch block patterns and super-response to cardiac resynchronization therapy in patients with heart failure

2021 ◽  
Vol 26 (7) ◽  
pp. 4227
Author(s):  
N. E. Shirokov ◽  
V. A. Kuznetsov ◽  
V. V. Todosiychuk ◽  
A. M. Soldatova ◽  
D. V. Krinochkin
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Bundle Branch Block ◽  
Interventricular Septum ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Bundle Branch Block ◽  
Septal Wall ◽  
Group I

Aim. To assess a relationship of left bundle branch block (LBBB) patterns defined by electrocardiography (ECG) and echocardiography with super-response (SR) to cardiac resynchronization therapy (CRT).Material and methods. Sixty patients (mean age, 54,5±10,4 years) were examined at baseline and during follow-up (10,6±3,6 months). Patients were divided into groups: group I (n=31) — decrease of left ventricular end-systolic volume (ESV) ≥30% (super-responders) and II group (n=29) — decrease of LV ESV <30% (non-super-responders). Three strain-markers of LBBB assessed by tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE) were used: early contraction of basal or midventricular segment in the septal wall and early stretching of basal or midventricular segment in the lateral wall (marker 1); early peak contraction of the septal wall occurred in the first 70% of the systolic ejection phase (marker 2, septal flash (SF)); early stretching wall that showed peak contraction after aortic valve closure (marker 3). The classical LBBB pattern was defined if all three strain-markers were present. The heterogeneous LBBB pattern was defined if two from three strain-markers were present.Results. At baseline, groups did not differ in main clinical characteristics, including QRS width and LBBB assessed by ECG. Mechanical abnormalities were found only in group I: SF (32,3% vs 0,0%; p=0,001) and apical rocking (19,4% vs 0,0%; p=0,024), as well as classic LBBB mechanical pattern (20,8% vs 0,0%; p=0,05). The complex of heterogeneous LBBB mechanical pattern (odds ratio (OR), 7,512; 95% CI, 1,434-39,632; р=0,025), interventricular mechanical delay (OR, 1,037; 95% CI, 1,005-1,071; р=0,017) and longitudinal strain of interventricular septum mid segment (OR, 0,726; 95% CI, 0,540-0,977; р=0,035) had an independent relationship with SR. According to the ROC analysis, the sensitivity and specificity of model in SR prediction were 77,3% and 91,3% (AUC=0,862; p<0,001).Conclusion. SR is associated with both LBBB mechanical patterns assessed by STE and TDI. LBBB defined by ECG did not have significant association with SR to CRT.

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