Elevating mitochondrial reactive oxygen species by mitochondria-targeted inhibition of superoxide dismutase with a mesoporous silica nanocarrier for cancer therapy

Nano Research ◽  
2014 ◽  
Vol 7 (8) ◽  
pp. 1103-1115 ◽  
Author(s):  
Yi Zhang ◽  
Zhengyan Hu ◽  
Guiju Xu ◽  
Chuanzhou Gao ◽  
Ren’an Wu ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Superoxide Dismutase ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Mitochondrial Reactive Oxygen Species ◽  
Targeted Inhibition

scholarly journals Ultrasound-induced reactive oxygen species generation and mitochondria-specific damage by sonodynamic agent/metal ion-doped mesoporous silica

RSC Advances ◽  
2019 ◽  
Vol 9 (68) ◽  
pp. 39924-39931 ◽  
Author(s):  
Kecan Lin ◽  
Ziguo Lin ◽  
Yujie Li ◽  
Youshi Zheng ◽  
Da Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Tumor Microenvironment ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Metal Ion ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Oxygen Species

Herein, we design tumor microenvironment specific active nano sono-chemodynamic agent for synergistic photodynamic–chemodynamic cancer therapy.

Enhanced highly toxic reactive oxygen species levels from iron oxide core–shell mesoporous silica nanocarrier-mediated Fenton reactions for cancer therapy

2018 ◽  
Vol 6 (37) ◽  
pp. 5876-5887 ◽  
Author(s):  
Kai Sun ◽  
Zhiguo Gao ◽  
Yu Zhang ◽  
Hongshuai Wu ◽  
Chaoqun You ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Iron Oxide ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Reactive Oxygen ◽  
Core Shell ◽  
Oxygen Species ◽  
Iron Oxide Core

Highly toxic reactive oxygen species levels were enhanced via iron oxide core–shell mesoporous silica nanocarrier-mediated Fenton reactions for cancer therapy.

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