Dental enamel defects and oral cavity manifestations in Asian patients with celiac disease

Background: Celiac disease is an autoimmune chronic disease that affects the human’s intestine and subsequently reflects its effect on the entire body health by retardation the absorption and immune mediated complications cause the involvement of oral health. The present study intended to evaluate the impact of the histopathological disease activity upon dental enamel defects and dental caries. Subjects and methods: Forty celiac-diseased patients aged 7-11 years were collected from 3 different teaching hospitals in Baghdad classified by means of the histopathological activity of the intestinal disease according to modified Marsh-Rostami classification. Dental enamel defects were measured by Aine’s classification, while dental caries experience and severity were measured using d1-4mfs/t and D1-4MFS/T. Results: The majority of the sample came with partial villous atrophy of the small intestine (Marsh III-a) and almost half of the sample were with no celiac disease specific dental enamel defects (Aine’s 0), while Aine’s I was the most predominant than Aine’s II. Most missed surfaces due to dental caries in permanent teeth came with Marsh II. Conclusion: The more the severity of celiac disease histopathological activity the more the severity of celiac specific dental enamel defects and the less experienced dental caries. Keywords: Celiac disease, histopathological activity, dental enamel defects, dental caries.

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Screening for Celiac Disease in Children with Dental Enamel Defects

ISRN Pediatrics ◽

10.5402/2012/763783 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 10

Author(s):

Mostafa Abdel-Aziz El-Hodhod ◽

Iman Ali El-Agouza ◽

Hala Abdel-Al ◽

Noha Samir Kabil ◽

Khaled Abd El-Moez Bayomi

Keyword(s):

Celiac Disease ◽

Serum Calcium ◽

Tissue Transglutaminase ◽

Gastrointestinal Symptoms ◽

Dental Enamel ◽

Deciduous Teeth ◽

Control Group ◽

Normal Children ◽

Enamel Defects ◽

Calcium Phosphorus

Background. Dental enamel defects (DEDs) are seen in celiac disease (CD). Aim was to detect frequency of CD among such patients. Methods. This study included 140 children with DED. They were tested for CD. Gluten-free diet (GFD) was instituted for CD patients. A cohort of 720, age and sex-matched, normal children represented a control group. Both groups were evaluated clinically. Serum calcium, phosphorus, alkaline phosphatase, serum IgA, and tissue transglutaminase (tTG) IgG and IgA types were measured. Results. CD was more diagnosed in patients with DEDs (17.86%) compared to controls (0.97%) (P<0.0001). Majority of nonceliac patients showed grade 1 DED compared to grades 1, 2, and 3 DED in CD. Five children had DED of deciduous teeth and remaining in permanent ones. After 1 year on GFD, DED improved better in CD compared to nonceliac patients. Gastrointestinal symptoms did not vary between celiac and nonceliac DED patients. Lower serum calcium significantly predicted CD in this cohort. Conclusion. CD is more prevalent among children with DED than in the general population. These DEDs might be the only manifestation of CD; therefore, screening for CD is highly recommended among those patients especially in presence of underweight and hypocalcemia.

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Dental Enamel Defects in Celiac Disease

The American Journal of Gastroenterology ◽

10.14309/00000434-200609001-00308 ◽

2006 ◽

Vol 101 ◽

pp. S146

Author(s):

Pardeep S. Brar ◽

Ted Malahias ◽

Peter H.R. Green

Keyword(s):

Celiac Disease ◽

Dental Enamel ◽

Enamel Defects

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Presence and Distribution of Dental Enamel Defects, Recurrent Aphthous Lesions and Caries Scores in Children with Celiac Disease

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.313.6960 ◽

1969 ◽

Vol 31 (3) ◽

Cited By ~ 4

Author(s):

Kenan Cantekin ◽

Ebru Delikan

Keyword(s):

Celiac Disease ◽

Dental Enamel ◽

Enamel Defects

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Prevalence of Dental Enamel Defects, Aphthous-Like Ulcers and Other Oral Manifestations in Celiac Children and Adolescents: A Comparative Study

Journal of Clinical Pediatric Dentistry ◽

10.17796/1053-4625-43.4.9 ◽

2019 ◽

Vol 43 (4) ◽

pp. 274-280 ◽

Cited By ~ 1

Author(s):

Michail Zoumpoulakis ◽

Maria Fotoulaki ◽

Vasiliki Topitsoglou ◽

Panagiota Lazidou ◽

Lambros Zouloumis ◽

...

Keyword(s):

Celiac Disease ◽

Soft Tissue ◽

Healthy Subjects ◽

Screening Tool ◽

Dental Enamel ◽

Oral Manifestations ◽

Age And Gender ◽

Diagnostic Screening ◽

Enamel Defects ◽

And Gender

Objectives: Celiac disease (CD) is an autoimmune disease with typical, atypical and asymptomatic forms, in which many oral manifestations have been recognized. This study aims to evaluate the prevalence of oral manifestations as well as explore if oral examination could be used as a first diagnostic screening tool for atypical or asymptomatic forms. Study Design: 45 CD patients, between 2 and 18 years (mean age 10.3) and 45 healthy subjects, age and gender-matched, were examined for hard and soft tissue lesions such as dental enamel defects (DED), dental caries, aphthous-like ulcers (ALU), atrophic glossitis, geographic tongue, median rhomboid glossitis. Results: Statistically significant differences between the two groups were observed for the prevalence of DED (in 64,4% CD and 24,46% control patients, p=0.001), their location in the teeth (incisal: p=0.0001, middle: p=0.002, cervical: p=0.007), as well as for the prevalence of ALU (in 40% CD as opposed to 4,44% control patients, p=0.001). Conclusion: The presence of DED and ALU could be used as a sign of alert for possible atypical and asymptomatic forms of CD.

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