Synthesis and Apoptotic Efficacy of Biosynthesized Silver Nanoparticles Using Acacia luciana Flower Extract in MCF-7 Breast Cancer Cells: Activation of Bak1 and Bclx for Cancer Therapy

2020 ◽  
Vol 10 (3) ◽  
pp. 683-689 ◽  
Author(s):  
Azam Sargazi ◽  
Amin Barani ◽  
Mostafa Heidari Majd
2013 ◽  
Vol 19 (5) ◽  
pp. 1600-1605 ◽  
Author(s):  
Sangiliyandi Gurunathan ◽  
Jae Woong Han ◽  
Ahmed Abdal Dayem ◽  
Vasuki Eppakayala ◽  
Jung Hyun Park ◽  
...  

YMER Digital ◽  
2021 ◽  
Vol 20 (12) ◽  
pp. 385-396
Author(s):  
Sumathi R ◽  
◽  
Sivagamasundari K ◽  

The present work demonstrates the influence of plant extract composition (antioxidant and total phenolic content) on the size and morphology of the produced AgNPs. In this study, silver nanoparticles (AgNPs) were synthesized using aqueous flower extract of Allamanda neriifolia plant. The biosynthetic procedure was rapid and simple and was easily monitored via colour changes and examined AgNPs (AN-AgNPs) by ultraviolet-visible spectroscopy, Fourier transform infrared (FTIR) spectroscopy and scanning electron microscope (SEM). The results obtained from various characterizations revealed that average size of synthesized AgNPs was 50 nm and in spherical structure. The anticancer potential of AN-AgNPs was investigated against human breast cancer cells (MCF-7). The cytotoxic response was assessed by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT), and morphological changes by apoptosis. The biosynthesized AgNPs-induced cell death in MCF- 7 cells suggested the anticancer potential of AN-AgNPs. Therefore, they may be used to treat the breast cancer cells.


2016 ◽  
Vol 8 (3) ◽  
pp. 545-553 ◽  
Author(s):  
Samer Hasan Hussein-Al-Ali ◽  
Sepideh Keshan Balavandy ◽  
Zurina Zainal Abidin ◽  
Aminu Umar Kura ◽  
Sharida Fakurazi ◽  
...  

2014 ◽  
Vol 32 (3) ◽  
pp. 278
Author(s):  
Dongdong SHI ◽  
Yuanyuan KUANG ◽  
Guiming WANG ◽  
Zhangxiao PENG ◽  
Yan WANG ◽  
...  

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