Germline mutations of BRCA1 gene exon 11 are not associated with platinum response neither with survival advantage in patients with primary ovarian cancer: understanding the clinical importance of one of the biggest human exons. A study of the Tumor Bank Ovarian Cancer (TOC) Consortium

Tumor Biology ◽  
2016 ◽  
Vol 37 (9) ◽  
pp. 12329-12337 ◽  
Author(s):  
Desislava Dimitrova ◽  
Ilary Ruscito ◽  
Sven Olek ◽  
Rolf Richter ◽  
Alexander Hellwag ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Clinical Importance ◽  
Brca1 Gene ◽  
Germline Mutations ◽  
Survival Advantage ◽  
Primary Ovarian Cancer ◽  
Tumor Bank ◽  
Exon 11 ◽  
Gene Exon

scholarly journals High proportion of recurrent germline mutations in the BRCA1 gene in breast and ovarian cancer patients from the Prague area

2005 ◽  
Vol 7 (5) ◽  
Author(s):  
Petr Pohlreich ◽  
Michal Zikan ◽  
Jana Stribrna ◽  
Zdenek Kleibl ◽  
Marketa Janatova ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Patients ◽  
Brca1 Gene ◽  
Germline Mutations ◽  
Breast And Ovarian Cancer

Mutation analysis of the BRCA1 gene in 76 Japanese ovarian cancer patients: four germline mutations, but no evidence of somatic mutation

1995 ◽  
Vol 4 (10) ◽  
pp. 1953-1956 ◽  
Author(s):  
Mieko Matsushima ◽  
Kanji Kobayashi ◽  
Mitsuru Eml ◽  
Junko Saito ◽  
Kaoru Suzumori ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Patients ◽  
Somatic Mutation ◽  
Mutation Analysis ◽  
Brca1 Gene ◽  
Germline Mutations

scholarly journals Variability of Fragments of Nuclear Brca1 Gene, Exon 11, and Mitochondrial Cox1 Gene in House Mice Mus musculus

2020 ◽  
Vol 54 (2) ◽  
pp. 185-195
Author(s):  
A. S. Bogdanov ◽  
A. N. Maltsev ◽  
E. V. Kotenkova ◽  
V. G. Malikov ◽  
A. A. Lissovsky ◽  
...  
Keyword(s):  
Mus Musculus ◽  
Brca1 Gene ◽  
House Mice ◽  
Cox1 Gene ◽  
Mitochondrial Cox1 ◽  
Exon 11 ◽  
Gene Exon

scholarly journals BRCA1 Gene Exon 11 Mutations in Uighur and Han Women with Early-onset Sporadic Breast Cancer in the Northwest Region of China

2014 ◽  
Vol 15 (11) ◽  
pp. 4513-4518 ◽  
Author(s):  
Yu-Wen Cao ◽  
Xin-Ge Fu ◽  
Guo-Xing Wan ◽  
Shi-Ying Yu ◽  
Xiao-Bin Cui ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Onset ◽  
Sporadic Breast Cancer ◽  
Brca1 Gene ◽  
Exon 11 ◽  
Northwest Region ◽  
Gene Exon

scholarly journals Inflammatory Breast Cancer from Metastatic Ovarian Cancer

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Vuthinun Achariyapota ◽  
Tuenjai Chuangsuwanich ◽  
Mongkol Benjapibal
Keyword(s):  
Breast Cancer ◽  
Ovarian Cancer ◽  
Inflammatory Breast Cancer ◽  
Clinical Importance ◽  
Advanced Ovarian Cancer ◽  
Metastatic Breast ◽  
Breast Cancers ◽  
Primary Ovarian Cancer ◽  
Cancer Metastases ◽  
Malignant Breast

Metastases to the breast from tumors other than breast carcinomas are extremely rare and represent only 0.2–1.3% of all diagnosed malignant breast tumors. Furthermore, while the most common sites for advanced ovarian cancer metastases are the liver, lung, and pleura, metastasis to the breast from a primary ovarian cancer is uncommon and has only been reported in 0.03–0.6% of all breast cancers. Here we describe a case report of a 50-year-old female patient with a rare case of breast metastases from an advanced ovarian cancer, presenting as inflammatory breast cancer. Our observations emphasize the clinical importance of distinguishing between primary and metastatic breast cancer during diagnosis for the purpose of appropriate prognosis and treatment.

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

1995 ◽  
Vol 11 (4) ◽  
pp. 428-433 ◽  
Author(s):  
Simon A. Gayther ◽  
William Warren ◽  
Sylvie Mazoyer ◽  
Paul A. Russell ◽  
Patricia A. Harrington ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Brca1 Gene ◽  
Germline Mutations ◽  
Phenotype Correlation ◽  
Breast And Ovarian Cancer ◽  
Genotype Phenotype Correlation

Tumor biology driven treatment selection in primary ovarian cancer

2014 ◽  
Vol 74 (S 01) ◽  
Author(s):  
F Arnold ◽  
D Margraf ◽  
O Hoffmann ◽  
K von Dehn-Rotfelser ◽  
I Funke ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Tumor Biology ◽  
Treatment Selection ◽  
Primary Ovarian Cancer

Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: A study by the Tumor Bank Ovarian Cancer (TOC)

2016 ◽  
Vol 76 (10) ◽  
Author(s):  
I Rohr ◽  
J Sehouli ◽  
A En-Nia ◽  
M Heinrich ◽  
R Richter ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Diagnosis ◽  
Serum Marker ◽  
Tumor Bank
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