The Combination of Concentrated Growth Factor and Adipose-Derived Stem Cell Sheet Repairs Skull Defects in Rats

2021 ◽  
Author(s):  
Tuqiang Hu ◽  
Hao Zhang ◽  
Wei Yu ◽  
Xuezhou Yu ◽  
Zubing Li ◽  
...  
Keyword(s):  
Stem Cell ◽  
Growth Factor ◽  
Cell Sheet ◽  
Skull Defects ◽  
Adipose Derived Stem Cell

Baculovirus-transduced, VEGF-expressing adipose-derived stem cell sheet for the treatment of myocardium infarction

Biomaterials ◽  
2014 ◽  
Vol 35 (1) ◽  
pp. 174-184 ◽  
Author(s):  
Tsung-Szu Yeh ◽  
Yu-Hua Dean Fang ◽  
Chia-Hsin Lu ◽  
Shao-Chieh Chiu ◽  
Chia-Lin Yeh ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Sheet ◽  
Myocardium Infarction ◽  
Adipose Derived Stem Cell

scholarly journals Adipose-derived stem cell sheet transplantation therapy in a porcine model of chronic heart failure

2015 ◽  
Vol 165 (5) ◽  
pp. 631-639 ◽  
Author(s):  
Osamu Ishida ◽  
Ikuo Hagino ◽  
Noritoshi Nagaya ◽  
Tatsuya Shimizu ◽  
Teruo Okano ◽  
...  
Keyword(s):  
Heart Failure ◽  
Stem Cell ◽  
Chronic Heart Failure ◽  
Porcine Model ◽  
Cell Sheet ◽  
Adipose Derived Stem Cell ◽  
Transplantation Therapy

scholarly journals Local Application of Semaphorin 3A Combined with Adipose-Derived Stem Cell Sheet and Anorganic Bovine Bone Granules Enhances Bone Regeneration in Type 2 Diabetes Mellitus Rats

2019 ◽  
Vol 2019 ◽  
pp. 1-14 ◽  
Author(s):  
Xiaoru Xu ◽  
Kaixiu Fang ◽  
Lifeng Wang ◽  
Xiangwei Liu ◽  
Yuchao Zhou ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Stem Cell ◽  
Bone Healing ◽  
Cell Sheet ◽  
Semaphorin 3A ◽  
Adipose Derived Stem Cell

Bone tissue regeneration is considered to be the optimal solution for bone loss. However, diabetic patients have a greater risk of poor bone healing or bone grafting failure than nondiabetics. The purpose of this study was to investigate the influence of the complexes of an adipose-derived stem cell sheet (ASC sheet) and Bio-Oss® bone granules on bone healing in type 2 diabetes mellitus (T2DM) rats with the addition of semaphorin 3A (Sema3A). The rat ASC sheets showed stronger osteogenic ability than ASCs in vitro, as indicated by the extracellular matrix mineralization and the expression of osteogenesis-related genes at mRNA level. An ASC sheet combined with Bio-Oss® bone granules promoted bone formation in T2DM rats as indicated by microcomputed tomography (micro-CT) and histological analysis. In addition, Sema3A promoted the osteogenic differentiation of ASC sheets in vitro and local injection of Sema3A promoted T2DM rats’ calvarial bone regeneration based on ASC sheet and Bio-Oss® bone granule complex treatment. In conclusion, the local injection of Sema3A and the complexes of ASC sheet and Bio-Oss® bone granules could promote osseous healing and are potentially useful to improve bone healing for T2DM patients.

Transplantation of Adipose-Derived Stem Cell Sheet Attenuates Adverse Cardiac Remodeling in Acute Myocardial Infarction

2017 ◽  
Vol 23 (1-2) ◽  
pp. 1-11 ◽  
Author(s):  
Jong-Ho Kim ◽  
Hyung Joon Joo ◽  
Mina Kim ◽  
Seung-Cheol Choi ◽  
Jeong Ik Lee ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Stem Cell ◽  
Cardiac Remodeling ◽  
Cell Sheet ◽  
Adipose Derived Stem Cell

scholarly journals Semaphorin 3A-modified adipose-derived stem cell sheet may improve osseointegration in a type 2 diabetes mellitus rat model

2016 ◽  
Vol 14 (3) ◽  
pp. 2449-2456 ◽  
Author(s):  
Kaixiu Fang ◽  
Wen Song ◽  
Lifeng Wang ◽  
Xiaoru Xu ◽  
Naiwen Tan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Stem Cell ◽  
Rat Model ◽  
Cell Sheet ◽  
Semaphorin 3A ◽  
Adipose Derived Stem Cell
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