Infective Endocarditis in Intravenous Drug Users from Italy: the Increasing Importance in HIV-infected Patients

Infection ◽  
2007 ◽  
Vol 35 (3) ◽  
pp. 154-160 ◽  
Author(s):  
F. G. De Rosa ◽  
S. Cicalini ◽  
F. Canta ◽  
S. Audagnotto ◽  
E. Cecchi ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Drug Users ◽  
Intravenous Drug ◽  
Intravenous Drug Users

scholarly journals Surgical and Medical Management of Isolated Tricuspid Valve Infective Endocarditis in Intravenous Drug Users

2015 ◽  
Vol 31 (2) ◽  
pp. 83-88 ◽  
Author(s):  
Nabha Shetty ◽  
Dave Nagpal ◽  
Sharon Koivu ◽  
Marko Mrkobrada
Keyword(s):  
Infective Endocarditis ◽  
Tricuspid Valve ◽  
Medical Management ◽  
Drug Users ◽  
Intravenous Drug ◽  
Intravenous Drug Users

Long-Term Outcome for the Surgical Treatment of Infective Endocarditis With a Focus on Intravenous Drug Users

2012 ◽  
Vol 93 (1) ◽  
pp. 51-57 ◽  
Author(s):  
David G. Rabkin ◽  
Nahush A. Mokadam ◽  
Donald W. Miller ◽  
Raymond R. Goetz ◽  
Edward D. Verrier ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Infective Endocarditis ◽  
Drug Users ◽  
Intravenous Drug ◽  
Intravenous Drug Users ◽  
Term Outcome ◽  
Long Term Outcome

scholarly journals Impact of Empirical-Therapy Selection on Outcomes of Intravenous Drug Users with Infective Endocarditis Caused by Methicillin-Susceptible Staphylococcus aureus

2007 ◽  
Vol 51 (10) ◽  
pp. 3731-3733 ◽  
Author(s):  
Thomas P. Lodise ◽  
Peggy S. McKinnon ◽  
Donald P. Levine ◽  
Michael J. Rybak
Keyword(s):  
Staphylococcus Aureus ◽  
Regression Analysis ◽  
Infective Endocarditis ◽  
Clinical Characteristics ◽  
Drug Users ◽  
Empirical Therapy ◽  
Intravenous Drug ◽  
Intravenous Drug Users ◽  
Beta Lactam ◽  
Related Mortality

ABSTRACT This study compares beta-lactam and vancomycin among intravenous drug users with infective endocarditis caused by methicillin-susceptible Staphylococcus aureus. Patients who received vancomycin had higher infection-related mortality, even if they were switched to beta-lactam once culture results became available; this relationship persisted after logistic regression analysis controlling for clinical characteristics.

scholarly journals A changing profile of infective endocarditis at a tertiary hospital in China: A retrospective study from 2001 to 2018

2019 ◽  
Author(s):  
Zuning Ren ◽  
Xichao Mo ◽  
Hongjie Chen ◽  
Jie Peng
Keyword(s):  
Infective Endocarditis ◽  
Medical Records ◽  
Drug Users ◽  
Southern China ◽  
Age At Onset ◽  
Early Period ◽  
Tertiary Hospital ◽  
Intravenous Drug ◽  
Intravenous Drug Users ◽  
The Right

Abstract Background: Infective endocarditis (IE) is a lethal disease which has been changing significantly over the past decades; however, information about IE in China remains scarce. This study surveyed the changes in clinical characteristics of IE at a tertiary hospital in southern China over a period of nearly eighteen years. Methods: Medical records with IE patients consecutively hospitalized between June 2001 and June 2018 were selected from the electronic medical records system in Nanfang Hospital of Southern Medical University. Data were divided by admission time into two groups: early-period group, June 2001 to December 2009 and later-period group, January 2010 to July 2018. Results: A Total of 313 IE patients were included in our study. Compared with the early-period group, patients in the later-period group included fewer intravenous drug users (IVDU), older age at onset, reduced development of pulmonary embolism, less renal dysfunction, decreased proportion of Staphylococcus aureus infection and fewer vegetations observed in the right heart by echocardiography. The later-period group also showed a higher proportion of ischemic strokes and higher rate of whole-blood culture positive compared with the early-period group. The in-hospital mortality rate remained about the same between the two periods. Conclusions: Our study demonstrated a dramatic change in the profile and characteristics of IE over a period of eighteen years at a tertiary hospital in southern China, especially the decrease in intravenous drug users (IVDU), which might be responsible for many other changes.

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