scholarly journals Baseline Characteristics and Outcomes Among Patients with Complicated Skin and Soft Tissue Infections Admitted to the Intensive Care Unit: Analysis of the Phase 3 COVERS Randomized Trial of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam

2020 ◽  
Vol 9 (3) ◽  
pp. 609-623
Author(s):  
Miguel Sánchez-García ◽  
Jennifer Hammond ◽  
Jean Li Yan ◽  
Michal Kantecki ◽  
Wajeeha Ansari ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Soft Tissue ◽  
Randomized Trial ◽  
Soft Tissue Infections ◽  
Phase 3 ◽  
Ceftaroline Fosamil ◽  
Complicated Skin ◽  
Baseline Characteristics ◽  
Unit Analysis

scholarly journals Necrotizing skin and soft-tissue infections in the intensive care unit

2020 ◽  
Vol 26 (1) ◽  
pp. 8-17 ◽  
Author(s):  
M. Peetermans ◽  
N. de Prost ◽  
C. Eckmann ◽  
A. Norrby-Teglund ◽  
S. Skrede ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Soft Tissue ◽  
Soft Tissue Infections

Necrotizing Skin and Soft Tissue Infections Admitted to Intensive Care Unit in Reunion Island: A Retrospective Cohort Study

2021 ◽  
Author(s):  
David Vandroux ◽  
Alexia Mubuanga Nkusu ◽  
Bernard-Alex Gauzere ◽  
Olivier Martinet
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Soft Tissue ◽  
Gram Negative Bacteria ◽  
Soft Tissue Infections ◽  
Reunion Island ◽  
Single Center Study ◽  
Patients With Diabetes ◽  
Réunion Island ◽  
Inflammatory Drugs

This retrospective and single-center study in Reunion Island (Indian Ocean) assessed frequency, mortality, causative pathogens of severe necrotizing skin, and necrotizing skin and soft tissue infections (NSSTIs) admitted in intensive care unit (ICU). Sixty-seven consecutive patients were included from January 2012 to December 2018. Necrotizing skin and soft tissue infection represented 1.06% of total ICU admissions. We estimate the incidence of NSSTI requiring ICU at 1.21/100,000 person/years in Reunion Island. Twenty (30%) patients were receiving nonsteroidal anti-inflammatory drugs (NSAIDs) prior to admission in ICU and 40 (60%) were diagnosed patients with diabetes. Sites of infection were the lower limb in 52 (78%) patients, upper limb in 4 (6%), and perineum in 10 (15%). The surgical treatment was debridement for 40 patients, whereas 11 patients required an amputation. The most commonly isolated microorganisms were Streptococci (42%) and Gram-negative bacteria (22%).The mortality rate was 25.4%. NSAIDs did not influence mortality when interrupted upon admission to ICU.

Management of necrotizing soft tissue infections in the intensive care unit: results of an international survey

2015 ◽  
Vol 41 (8) ◽  
pp. 1506-1508 ◽  
Author(s):  
Nicolas de Prost ◽  
◽  
Emilie Sbidian ◽  
Olivier Chosidow ◽  
Christian Brun-Buisson ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Soft Tissue ◽  
Soft Tissue Infections ◽  
International Survey ◽  
Necrotizing Soft Tissue Infections

Understanding necrotizing soft tissue infections in the intensive care unit

2020 ◽  
Vol 46 (9) ◽  
pp. 1739-1742 ◽  
Author(s):  
Tomas Urbina ◽  
Martin Bruun Madsen ◽  
Nicolas de Prost
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Soft Tissue ◽  
Soft Tissue Infections ◽  
Necrotizing Soft Tissue Infections
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