Piracetam for Aphasia in Post-stroke Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials

CNS Drugs ◽  
2016 ◽  
Vol 30 (7) ◽  
pp. 575-587 ◽  
Author(s):  
Jie Zhang ◽  
Ruili Wei ◽  
Zhongqin Chen ◽  
Benyan Luo
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Stroke Patients ◽  
Post Stroke ◽  
Randomized Controlled

scholarly journals Cognitive rehabilitation interventions after stroke: protocol for a systematic review and meta-analysis of randomized controlled trials

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Qing Zhao ◽  
Xue Wang ◽  
Tao Wang ◽  
Adam A. Dmytriw ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cognitive Impairment ◽  
Randomized Controlled Trials ◽  
Cognitive Rehabilitation ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Post Stroke ◽  
Randomized Controlled

Abstract Background Stroke is the second leading cause of death worldwide, and 53.4% of stroke survivors suffer from post-stroke cognitive impairment. Post-stroke cognitive impairment can increase hospitalization rate and cost of care and decrease the quality of life of stroke patients. To date, multiple cognitive rehabilitation interventions have been tested in stroke populations with post-stroke cognitive impairment. However, the most efficacious intervention has not been established. This systematic review aims to compare the efficacy of cognitive rehabilitation interventions for patients with post-stroke cognitive impairment. Methods We will search MEDLINE, EMBASE, CENTRAL, PsycINFO, CINAHL, PubMed, and clinical trial registries to identify eligible randomized clinical trials with no restrictions in the date of publication and language. Studies conducted with patients aged 18 or over, with the presence of cognitive impairment after being diagnosed with stroke will be included. Studies will be restricted to randomized controlled trials comparing a cognitive rehabilitation intervention with another intervention. The primary outcome is any clinical changes in the general or specific cognitive domain (e.g., executive function, attention, memory, or perception). The secondary outcomes that will be collected include adverse effects (e.g., stroke, disability, or mortality) and quality of life. Two independent reviewers will assess articles to identify trials eligible for inclusion. Data extraction and risk of bias assessment of the included studies will also be done independently. Any discrepancies will be solved by discussion, or a third reviewer will be consulted if necessary. A meta-analysis will be carried out if appropriate. Discussion This systematic review for patients with post-stroke cognitive impairment will assess the efficacy of cognitive rehabilitation interventions. And our results will help clinical decision-making and support the development of clinical practice guidelines. Trial registration Systematic review registration: PROSPERO CRD42020173988

MUSIC THERAPY FOR STROKE PATIENTS: A SYSTEMATIC REVIEW WITH META-ANALYSIS

2019 ◽  
Vol 4 ◽  
pp. 287
Author(s):  
Sanita Šuriņa ◽  
Jana Duhovska ◽  
Kristīne Mārtinsone
Keyword(s):  
Systematic Review ◽  
Music Therapy ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Auditory Stimulation ◽  
Controlled Trials ◽  
Stroke Patients ◽  
Randomized Controlled ◽  
Rhythmic Auditory Stimulation ◽  
Arm Function

There are numerous trials, showing positive results for using the music therapy for stroke patient rehabilitation. Therefore, summarizing the data from these trials is an actual topic. The objective, of this research, was to summarize the data from trials about the use of music therapy methods and techniques, especially the rhythmic auditory stimulation, for improving of the motor functions for stroke patients, by creating a systematic review of randomized controlled trials, with meta-analysis. The trials where searched in MEDLINE, Cochrane Trial Register and EBSO databases. The trial quality was evaluated by the PEDro scale. 20 randomized controlled trials were included in the systematic review. The meta-analysis for 5 gait outcomes, including gait speed, steps per minute, step length, gait symmetry, Time up and go test, and 7 arm function outcomes, including Fugl-Meyer test, ARAT test, Box and blocks test, Wolf motor function test, Nine hole peg test, shoulder flexion, elbow extension, was conducted. According to the results of the meta-analysis, gait exercises, combined with rhythmic auditory stimulation, provide statistically significant improvement, compared with gait exercises alone. Concerning the use of rhythmic auditory stimulation and other music therapy interventions for arm function rehabilitation, a statistically significant improvement was not detected.  

The Impact of Immersive and Non-Immersive Virtual Reality Trends in Sensorimotor Recovery of Post-Stroke Patients-A Meta-Analysis

2021 ◽  
Vol 9 (5) ◽  
pp. 555-564
Author(s):  
Jaza Rizvi ◽  
◽  
Abid Khan ◽  
Sumaira Imran Farooqui ◽  
Bashir Ahmed Soomro ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Stroke Patients ◽  
Post Stroke ◽  
Randomized Controlled ◽  
Sensorimotor Recovery ◽  
The Impact

Virtual Reality (VR) is an approach in stroke rehabilitation with ever-improving technological advancement for targeted motor rehabilitation by providing a user interface in a simulated environment with proprioceptive and visual feedback. This meta-analysis intended to evaluate the impact of immersive and non-immersive VR-based interventions compared to conventional rehabilitation in sensorimotor recovery following stroke. Randomized Controlled Trials based on the impact of VR, either immersive or non-immersive type in comparison to conventional rehabilitation on post-stroke patients (>18 years) sensorimotor recovery were searched on six databases including Google Scholar, PEDro, MEDLINE, Cochrane Library, EMBASE, and Web of Science from August to November 2020. A total of 17 randomized controlled trials on VR based intervention showed significant improvement in sensorimotor recovery following a stroke in overall FMA outcomes in comparison to the control group with pool effects in terms of SMD in a random effect model showed an impact of 0.498 at 95% CI (p<0.001) depicts a moderate effect size. An immersive and non-immersive emerging VR trend appears to be a promising therapeutic tool in sensorimotor recovery following stroke.

Effects of isokinetic muscle strengthening on muscle strength, mobility, and gait in post-stroke patients: a systematic review and meta-analysis

2018 ◽  
Vol 33 (3) ◽  
pp. 381-394 ◽  
Author(s):  
Sarah Souza Pontes ◽  
Ana Louise Reis de Carvalho ◽  
Katna de Oliveira Almeida ◽  
Murilo Pires Neves ◽  
Ingara Fernanda Silva Ribeiro Schindler ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Randomized Controlled Trials ◽  
Weighted Mean Difference ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Stroke Patients ◽  
Muscle Strengthening ◽  
Post Stroke ◽  
Randomized Controlled

Objective: To investigate whether isokinetic muscle strengthening improves muscle strength, mobility, and gait in post-stroke patients. Methods: We searched for randomized controlled trials at PubMed/Medline, SciELO, PEDro, and Cochrane Central Register of Controlled Trials, from the earliest date available to June 2018. Randomized controlled trials that examined the effects of isokinetic muscle strengthening versus other rehabilitation interventions or control in post-stroke patients were included. Study quality was evaluated using the PEDro scale. Weighted mean difference (WMD) and 95% confidence intervals (CIs) were calculated, and heterogeneity was assessed using the I2 test. Results: In total, 13 studies (347 patients) focusing on the use of isokinetic in rehabilitation following stroke were included. All trials were of low-to-moderate quality. Isokinetic muscle strengthening improved muscle strength WMD 0.8 (95% CI: 0.2, 1.4; N = 96), mobility WMD −2.03 seconds (95% CI: −2.9, −1.1; N = 111) and gait speed WMD 0.9 m/s (95% CI: 0.05, 1.8; N = 87). Conclusion: Isokinetic muscle strengthening seems to be a useful strategy for improving muscle strength, mobility, and gait in post-stroke patients.

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