scholarly journals Green cardamom plus low-calorie diet can decrease the expression of inflammatory genes among obese women with polycystic ovary syndrome: a double-blind randomized clinical trial

2021 ◽  
Author(s):  
Sahar Cheshmeh ◽  
Maysa Ghayyem ◽  
Firoozeh Khamooshi ◽  
Neda Heidarzadeh-Esfahani ◽  
Negin Rahmani ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Polycystic Ovary Syndrome ◽  
Randomized Clinical Trial ◽  
Polycystic Ovary ◽  
Obese Women ◽  
Ovary Syndrome ◽  
Double Blind ◽  
Low Calorie Diet ◽  
Calorie Diet ◽  
Green Cardamom

scholarly journals The Effect of Vitamin D Supplementation on Anthropometric Indices and Total Testosterone in Women with Polycystic Ovary Syndrome Treated with Low Calorie Diet: A Randomized Clinical Trial

2019 ◽  
Vol 12 (11) ◽  
pp. 10-22
Author(s):  
Samira Jafari-Sfidvajani ◽  
Roghayeh Ahangari ◽  
Mohammad Hozoori ◽  
Hassan Mozaffari-Khosravi ◽  
Hossein Fallahzadeh ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Vitamin D Supplementation ◽  
Total Testosterone ◽  
Ovary Syndrome ◽  
Anthropometric Indices ◽  
Low Calorie Diet ◽  
Calorie Diet

Effects of Green Cardamom Supplementation on Obesity and Diabetes Gene Expression Among Obese Women With Polycystic Ovary Syndrome; A Double Blind Randomized Controlled Trial

2021 ◽  
Author(s):  
Sahar Cheshmeh ◽  
Negin Elahi ◽  
Maysa Ghayyem ◽  
Elahe Mosayebi ◽  
Shima Moradi ◽  
...  
Keyword(s):  
Polycystic Ovary ◽  
Intervention Group ◽  
Obese Women ◽  
Ovary Syndrome ◽  
Low Calorie ◽  
Low Calorie Diet ◽  
Obesity And Diabetes ◽  
Genes Expression ◽  
Calorie Diet ◽  
Green Cardamom

Abstract BackgroundPolycystic ovary syndrome (PCOS) is an endocrine disease in which related obesity, metabolic disorders and is considered as one of the main causes of infertility in women. This trial was investigated the effects of green cardamom on obesity and diabetes genes expression among obese women with PCOS.Methods194 PCOS women were randomly divided two groups: intervention (n= 99; 3 g/day green cardamom) and control groups (n=95). All of them were given low calorie diet. Anthropometric, glycemic and androgen hormones were assessed before and after 16 weeks’ intervention. Fat mass and obesity-associated (FTO), Peroxisome proliferative activating Receptor-γ (PPAR-γ) Carnitine Palmitoyltransferase 1A (CPT1A), Acetyl-CoA Carboxylase Beta (ACAB), Leptin Receptor (LEPR), Gherlin, and lamin A/C (LAMIN) genes in PBMC were measured in each group using reverse transcription-polymerase chain reaction (RT-PCR) method.ResultsAnthropometric indices were significantly decreased after intervention in both two studied groups. Glycemic indices and androgen hormones were significantly improved in the intervention group. The expression level of FTO, CPT1A, LEPR, and LAMIN were significantly down-regulated (P<0.001), as well as, PPAR-y was significantly up-regulated in the intervention group after intervention with green cardamom (P<0.001). ConclusionThis current study showed that the administration of green cardamom is a beneficial approach for improving of anthropometric, glycemic and androgen hormones, as well as, obesity and diabetes genes expression in PCOS women under low calorie diet. This trial was registered with the Iranian Clinical Trials Registry (registration number: IRCT20200608047697N1). 1 August, 2020; https://www.irct.ir/trial/48748

Effects of DASH diet on lipid profiles and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: A randomized clinical trial

Nutrition ◽  
2014 ◽  
Vol 30 (11-12) ◽  
pp. 1287-1293 ◽  
Author(s):  
Zatollah Asemi ◽  
Mansooreh Samimi ◽  
Zohreh Tabassi ◽  
Hossein Shakeri ◽  
Sima-Sadat Sabihi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Clinical Trial ◽  
Polycystic Ovary Syndrome ◽  
Randomized Clinical Trial ◽  
Polycystic Ovary ◽  
Lipid Profiles ◽  
Obese Women ◽  
Ovary Syndrome ◽  
Dash Diet ◽  
Biomarkers Of Oxidative Stress

Green Cardamom Plus Low Calorie Diet Can Decrease Inflammatory Genes Expression Among Obese Women With Poly Cystic Ovarian Syndrome, A Double Blind Randomized Clinical Trial

2021 ◽  
Author(s):  
Sahar Cheshmeh ◽  
Maysa Ghayyem ◽  
Firoozeh Khamooshi ◽  
Neda Heydarzadeh ◽  
Niloofar Hojati ◽  
...  
Keyword(s):  
Expression Level ◽  
Low Grade ◽  
Obese Women ◽  
Double Blind ◽  
Low Calorie ◽  
Low Calorie Diet ◽  
Genes Expression ◽  
Tnf Α ◽  
Calorie Diet ◽  
Green Cardamom

Abstract PurposePolycystic ovary syndrome (PCOS) is a common cause of endocrine disorder and infertility among womenin which is related with low grade inflammation. Therefore, this current randomized, double-blind, placebo-controlledclinical trial assessed the effects of green cardamom supplementation on inflammatory markers and gene expressionamong obese women with PCOS.MethodsWe included 194 obese PCOS women that gave all of them low calorie diet. These subjects were randomlydivided in two studied groups including intervention with 3 g/day green cardamom (n=99) and placebo groups (n=95).Anthropometric indices, androgen hormones, and inflammatory factors (tumor necrosis factor-a (TNF-α), Interleukin6 (IL-6), and C- reactive protein (CRP)) were assessed before and after four months intervention. Their TNF-α, IL-6,and CRP genes expression level were measured using reverse transcription-polymerase chain reaction (RT-PCR)method.ResultsAnthropometric indices were improved in both two studied groups (P<0.001). Among androgen hormonesluteinizing hormone, androstenedione, and dehydroepiandrosterone were significantly decreased (P<0.001), as wellas, follicle-stimulating hormone was significantly increased (P<0.001) in the green cardamom group. Our findingsshowed that TNF-α, IL-6, and CRP serum were significantly decreased after the intervention with green cardamomplus low calorie diet (P<0.001). In addition, the expression level of TNF-α and CRP genes were significantly decreasedin intervention groups (P<0.001).ConclusionsThis present study support the beneficial anti-inflammatory effect of green cardamom on theinflammatory status in the PCOS women.Level of evidenceLevel I, randomized clinical trialTrial registrationThis trial was registered with the Iranian Clinical Trials Registry (registration number:IRCT20200608047697N1). 1 August, 2020; https://www.irct.ir/trial/48748

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