House dust mites known to be an allergen source for 50 years: Der p 1 still detectable in the original sample

Bedding dust is a mixture of many components, of which the house dust mite (HDM) allergen, Der p 1, is the most allergenic. There has been little work to investigate the effect of other bedding dust components on HDM sensitisation. The objective of the study was to determine the effect of endotoxin in bedding dust on the allergic response in HDM-sensitised individuals. Twenty-nine house dust mite-sensitised adults were skin prick and allergen patch tested against a sterile solution of their own bedding dust and against a solution containing the same concentration of Der p 1 as the bedding solution for comparison. There was no significant difference in wheal size between the diluted house dust mite solution and the bedding dust in spite of their high levels of endotoxin. Symptomatic subjects had larger, but not statistically significant, responses to commercial house dust mite solution than asymptomatic subjects. Allergen patch test responses were negative in 22/29 of subjects using either bedding dust solutions or comparable diluted house dust mite solutions. An individual's own bedding dust does not appear to contain factors that enhance skin prick test or atopy patch test responses to house dust mites.

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House dust mites (Der p 1, Der f 1), cat (Fel d 1) and cockroach (Bla g 2) allergens in indoor work-places (offices and archives)

The Science of The Total Environment ◽

10.1016/j.scitotenv.2004.01.028 ◽

2004 ◽

Vol 328 (1-3) ◽

pp. 15-21 ◽

Cited By ~ 10

Author(s):

L PERFETTI ◽

M FERRARI ◽

E GALDI ◽

V POZZI ◽

D COTTICA ◽

...

Keyword(s):

House Dust ◽

House Dust Mites ◽

Dust Mites ◽

Fel D 1 ◽

Der P 1

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Der p 1 and Der f 1, the highly related and major allergens from house dust mites, are differentially affected by a plant cystatin

Clinical & Experimental Allergy ◽

10.1046/j.1365-2222.2000.00845.x ◽

2000 ◽

Vol 30 (7) ◽

pp. 972-978 ◽

Cited By ~ 19

Author(s):

Pernas ◽

Sanchez-Ramos ◽

Sanchez-Monge ◽

Lombardero ◽

Arteaga ◽

...

Keyword(s):

House Dust ◽

House Dust Mites ◽

Dust Mites ◽

Der P 1 ◽

Major Allergens ◽

Plant Cystatin

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Phylogenetic analysis of house dust mites

Open Medicine ◽

10.2478/s11536-009-0106-6 ◽

2010 ◽

Vol 5 (1) ◽

pp. 69-74 ◽

Cited By ~ 1

Author(s):

Yubao Cui ◽

Cuixiang Gao ◽

Ying Zhou ◽

Peng Zhou ◽

Ming Peng ◽

...

Keyword(s):

Amino Acid ◽

House Dust ◽

Phylogenetic Trees ◽

Allergic Diseases ◽

Amino Acid Sequences ◽

House Dust Mites ◽

Dust Mites ◽

Der P 1 ◽

The Many ◽

Euroglyphus Maynei

AbstractHouse dust mites live in house dusts and affect the health of humans. Among the many species, Dermatophagoides farinae, D. pteronyssinus, and Euroglyphus maynei have been found to be commonly associated with Ig-E-mediated allergic diseases. As a result, there is increasing effort to develop methods for the diagnosis and treatment of diseases caused by these species. The purpose of the current study was to explore the evolutionary relationships among house dust mites. After adult D. farinae were separated and isolated for total RNA extract, the cDNA coding for Der f 1 and Der f 2 were cloned and sequenced. Then amino acid sequences for group 1 and 2 allergens of two of the most common house dust mites, D. pteronyssinus, E. maynei, were obtained from databases. Interestingly, homological analysis of amino acid sequences showed that both Der p 1 and Der p 2 from D. pteronyssinus had more similarities to Eur m 1 and Eur m 2, respectively, than they had to Der f 1 and Der f 2 from D. farinae. In the phylogenetic trees, D. pteronyssinus clustered with E. maynei, but not with D. farinae, although D. pteronyssinus and D. farinae belong to the same genus according to morphological taxonomy. It was previously assumed that D. pteronyssinus was more similar to E. maynei than to D. farinae at evolutionary levels.

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A novel IoT architecture for measuring and visualizing influence of common factors on house dust concentration

International journal of digital technology & economy ◽

10.31785/ijdte.4.1.1 ◽

2021 ◽

Vol 4 (1) ◽

pp. 1-8

Author(s):

Goran Đambić ◽

Danijel Kučak ◽

Tomislav Ražov

Keyword(s):

House Dust ◽

Common Factors ◽

Dust Concentration ◽

House Dust Mites ◽

Allergic Reactions ◽

Dust Mites ◽

Airborne Dust ◽

Allergen Source ◽

Settled Dust ◽

Do So

The house dust mites are considered to be an allergen source and a main cause of allergic rhinitis and allergic asthma. House dust mites, their feces and other allergens which they produce are usually major constituents of house dust. Any stir in the air causes settled dust, and therefore allergen source found in it, to become airborne and thus easier to be inhaled by people, possibly causing different kinds of allergic reactions (sneezing, for example). In this paper, the correlation between common home activities (walking around, bed making, vacuuming etc.) and airborne dust concentration is examined. In order to do so, a novel Internet of things architecture is proposed that is capable of establishing that correlation. This proposed system not only collects dust concentration but it also visualizes it in an easy to understand and interpret way.

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