scholarly journals Interstitial Lung Diseases and Air Pollution: Narrative Review of Literature

2021 ◽  
Author(s):  
Nishtha Singh ◽  
Sheetu Singh
Author(s):  
Lucile Sesé ◽  
Florence Jeny ◽  
Yurdagül Uzunhan ◽  
Warda Khamis ◽  
Olivia Freynet ◽  
...  

2020 ◽  
Vol 202 (9) ◽  
pp. 1217-1224 ◽  
Author(s):  
Gillian C. Goobie ◽  
Mehdi Nouraie ◽  
Yingze Zhang ◽  
Daniel J. Kass ◽  
Christopher J. Ryerson ◽  
...  

2020 ◽  
Vol 29 (157) ◽  
pp. 200093 ◽  
Author(s):  
Sergio Harari ◽  
Ganesh Raghu ◽  
Antonella Caminati ◽  
Mario Cruciani ◽  
Massimo Franchini ◽  
...  

BackgroundAir pollution is hypothesised to be a risk factor for interstitial lung diseases (ILD). This study systematically reviewed the literature regarding the impact of air pollution on idiopathic pulmonary fibrosis (IPF) and fibrotic interstitial lung diseases (ILD).MethodsA computer-assisted literature search of electronic databases was performed to identify studies focused on the association between ILDs and air pollution. Other inclusion criteria required that the article had to be: 1) original; 2) a prospective or retrospective study; and 3) fully published in English. Both randomised clinical trials and observational studies were considered.ResultsOnly seven studies met the inclusion criteria. All studies investigated the relationship between pollution and IPF, except one that dealt with the relationship between pollution and hypersensitivity pneumonitis. Outcome measures included exacerbation of IPF, mortality, disease severity, prevalence of hypersensitivity pneumonitis, progression and incidence of IPF. On the whole, air pollution levels were negatively associated with outcomes in patients with IPF and fibrotic ILD outcome. The heterogeneity in the measurement and reporting of the end-points limited the performance of a quantitative synthesis of data.ConclusionsThis systematic review provides supporting evidence linking exposure to air pollution to poor outcomes in patients with IPF and fibrotic ILD.


2021 ◽  
Vol 15 ◽  
pp. 175346662110397
Author(s):  
Anoop M. Nambiar ◽  
Christopher M. Walker ◽  
Jeffrey A. Sparks

Close monitoring of patients with fibrosing interstitial lung diseases (ILDs) is important to enable prompt identification and management of progressive disease. Monitoring should involve regular assessment of physiology (including pulmonary function tests), symptoms, and, when appropriate, high-resolution computed tomography. The management of patients with fibrosing ILDs requires a multidisciplinary approach and should be individualized based on factors such as disease severity, evidence of progression, risk factors for progression, comorbidities, and the preferences of the patient. In this narrative review, we discuss how patients with fibrosing ILDs can be effectively monitored and managed in clinical practice.


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