Diarrhea Is Associated with Increased Severity of Disease in COVID-19: Systemic Review and Metaanalysis

Abstract Background Evidence of various cardiac arrhythmias in septic patients has been demonstrated by multiple clinical reports and observations .Most cardiac arrhythmias in sepsis are new-onset and may be related to sepsis-induced myocardial dysfunction, autonomic dysfunction and, most likely also, by impairment and involvement of the cardiac conduction system. Aim of the Work to describe the incidence of NOAF and to determine the risk factors associated with its development, as well as its clinical course and its effect on the outcome of patients with sepsis admitted to the ICU. Patients and Methods A systematic search was conducted to retrieve articles that investigated the association of NOAF in patients diagnosed with sepsis. We identified potential Englishlanguage sources from the PubMed, Medline, and EMBASE databases. Keywords used were “atrial fibrillation” and (“sepsis” or “septic shock”). In addition, reference lists of any studies meeting inclusion criteria were reviewed manually to identify additional relevant publications. Results In our meta-analysis, we found that NOAF is a common occurrence in critically ill patients with sepsis, and its incidence rises with increasing severity of disease. Also, we found that NOAF in sepsis patients is significantly associated with increased risk of ICU. In hospital, and After hospital discharge mortality, as well as, increased risk of developing ischemic stroke. Conclusion NOAF is a common occurrence in critically ill patients with sepsis, and its incidence rises with increasing severity of disease. Our Meta-analysis suggests that it is independently associated with poor outcome. In view of these findings there is a need for better quality observational studies, because reliable identification of patients with sepsis who are prone for the development of AF may allow for early pharmacological interventions to prevent this complication.

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Association between symptoms and severity of disease in hospitalised novel coronavirus (COVID-19) patients: A systemic review and meta-analysis

10.21203/rs.3.rs-31795/v1 ◽

2020 ◽

Author(s):

Ashis Talukder ◽

Shaharior Rahman Razu ◽

Sheikh Alif ◽

Muhammad Aziz Rahman ◽

Sheikh Mohammed Shariful Islam

Keyword(s):

Meta Analysis ◽

Viral Disease ◽

Systemic Review ◽

Cochrane Library ◽

Medical Attention ◽

Chronic Obstructive ◽

Respiratory Illnesses ◽

Severity Of Disease ◽

Severity Of The Disease ◽

Novel Coronavirus

Abstract Background Symptoms of the novel coronavirus disease (COVD-19) are well known, although asymptomatic cases were also reported due to this rapidly evolving viral disease. However, there has been limited research with inconsistent findings on symptoms of COVID-19 and diseases severity. We aimed to evaluate the association between symptoms and severity of disease in confirmed COVID-19 cases by performing a meta-analysis.Methods We conducted a systematic review by searching four online databases (Medline, Web of Science, EMBASE and Cochrane library) of published studies that included symptoms of COVID-19 cases and severity of the disease between 01-Jan-2020 and 20-Apr-2020. PRISMA and MOOSE guidelines were followed, and only articles published in English were selected. We performed meta-analysis using Mantel-Haenszel random-effects model. Degree of heterogeneity among studies and quality of the selected studies were evaluated.Results Out of 153 articles identified, a total of seven articles, including 3,168 participants, met the inclusion criteria and were included. The median age of the patients was 49 years, 1818 (57.38%) were males, and 574 (18.11%) reported severe conditions. Fever was the most commonly reported symptom in the reported COVID-19 confirmed cases (87.89%, 95% CI: 83.22–81.39%), which was followed by cough, myalgia or fatigue, and less proportionally dyspnea and headache. Dyspnea was the only symptom, which was associated with severity of COVID-19 (OR 2.38, 95% CI: 1.83–3.10).Conclusions Dyspnoea was found to be associated with severity of COVID-19. People with existing respiratory illnesses, such as chronic obstructive pulmonary diseases need to be careful about the onset of such symptom and should seek medical attention.

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Abstract #609: Childhood Predictors of Cardiovasular Disease in Adulthood. A Systemic Review and Meta-Analysis

Endocrine Practice ◽

10.1016/s1530-891x(20)44486-6 ◽

2017 ◽

Vol 23 ◽

pp. 125-126

Author(s):

Olubukola Ajala ◽

Freda Mold ◽

Charlotte Broughton ◽

Debbie Cooke ◽

Martin Whyte

Keyword(s):

Meta Analysis ◽

Systemic Review ◽

Childhood Predictors

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SOOTY MOULD DISEASES OF SOME TREES FROM AURANGABAD DISTRICT, MAHARASHTRA (INDIA)

FLORA AND FAUNA ◽

10.33451/florafauna.v23i2pp351-354 ◽

2017 ◽

Vol 23 (2) ◽

Author(s):

NAVALSINGH J. TODAWAT

Keyword(s):

Surface Area ◽

Fungal Pathogens ◽

Leaf Surface ◽

Severity Of Disease ◽

Sooty Mould ◽

Leaf Surface Area

Sooty mould diseases of Tress from Aurangabad district were surveyed. During the survey of tress, 5 species were found infected by fungal pathogens causing sooty mould diseases. Disease is easily identifiable by the presence of a black, velvety growth covering the leaf surface area. The fungus produces mycelium which is superficial and dark grows on the flowers, leaf, stem and sometime on fruits also. The severity of disease depends on the honeydew secretions by insects. The diseases were found to be caused by 5 species of fungi viz. Capnodium anonae, C. ramosum, Capnodium sp., Meliola bangalorensis and Meliola ranganthii.

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