The relative rates of degradation of the plasma membrane glycoproteins from normal rat liver

1975 ◽  
Vol 389 (1) ◽  
pp. 154-161 ◽  
Author(s):  
J. Landry ◽  
N. Marceau
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Membrane Glycoproteins ◽  
Normal Rat

scholarly journals Functional localization of glucose transporter 2 in rat liver.

1996 ◽  
Vol 44 (11) ◽  
pp. 1231-1236 ◽  
Author(s):  
A Ogawa ◽  
K Kurita ◽  
Y Ikezawa ◽  
M Igarashi ◽  
T Kuzumaki ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Phosphoenolpyruvate Carboxykinase ◽  
Glucose Transporter ◽  
Mrna Level ◽  
Functional Difference ◽  
Isolation Technique ◽  
Glucose Transporter 2 ◽  
Normal Rat ◽  
Basolateral Plasma Membrane

Heterogeneity of zonal hepatocytes is important to elicit specific liver function. We investigated the distribution of glucose transporter 2 (GLUT-2) in normal rat liver by immunostaining and Northern blot analysis. GLUT-2 stained by immunohistochemistry was distributed predominantly in the periportal hepatocytes and gradually thinned towards the perivenous zone. Ultrastructural immunostaining of GLUT-2 showed that it was localized on microvilli of the sinusoidal plasma membrane of hepatocytes but not on the basolateral plasma membrane. Consistent with the distribution of GLUT-2 protein, the level of GLUT-2 mRNA in periportal hepatocytes was 1.9-fold higher than in perivenous hepatocytes selectively isolated by the differential isolation technique. In addition, the mRNA level of phosphoenolpyruvate carboxykinase, one of the key enzymes of gluconeogenesis, was also twofold higher in the periportal hepatocytes. These results suggest that GLUT-2 contributes to the functional difference between periportal and perivenous hepatocytes in glucose metabolism of the liver.

Protein-Restricted diet alters concentration of plasma membrane glycoproteins in rat liver

1996 ◽  
Vol 31 (4) ◽  
pp. 546-551
Author(s):  
Shimon Reif ◽  
Mamdouh El-Bendary ◽  
Yoram Bujanover ◽  
James K. Petell ◽  
Emanuel Lebenthal
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Membrane Glycoproteins ◽  
Restricted Diet ◽  
Protein Restricted Diet

scholarly journals A Freeze-Fracture Study of the Plasma Membrane of the Ito Cell in the Normal Rat Liver

1987 ◽  
Vol 50 (1) ◽  
pp. 95-102
Author(s):  
Kazuo TAIRA ◽  
Takeo AOKI ◽  
Susumu SHIBASAKI
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Freeze Fracture ◽  
Ito Cell ◽  
Normal Rat ◽  
Fracture Study
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