Substrate-specific differences in the rate of bile acid carrier reorientation: studies on human placental basal vesicles

1992 ◽  
Vol 1111 (1) ◽  
pp. 139-141
Author(s):  
N. Eleno ◽  
C.A.R. Boyd ◽  
J.J.G. Marin
Keyword(s):  
1987 ◽  
Vol 242 (2) ◽  
pp. 465-469 ◽  
Author(s):  
P J Meier ◽  
A S Meier-Abt ◽  
J L Boyer

4,4-Di-isothiocyanostilbene-2,2′-disulphonic acid inhibition of taurocholate efflux from canalicular vesicles was used to demonstrate that potential driven and ‘carrier’-mediated canalicular excretion of taurocholate occur via a common, rather than two separate, pathways. This electrogenic canalicular bile acid ‘carrier ’ preferentially transports trihydroxylated and conjugated dihydroxylated bile acids, but not the unphysiological oxo bile acids, and possibly extends its substrate specificity to other amphipathic molecules such as sulphobromophthalein.


Metallomics ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 1563-1575
Author(s):  
Jono W. Betts ◽  
Patrick Roth ◽  
Calum A. Pattrick ◽  
Hannah M. Southam ◽  
Roberto M. La Ragione ◽  
...  

Mn and Re tricarbonyl bile acid conjugates exhibit low micromolar MIC values and rescue Galleria larvae from bacterial infection.


2009 ◽  
Vol 47 (05) ◽  
Author(s):  
J Maléth ◽  
Z Rakonczay ◽  
V Venglovecz ◽  
Z Rázga ◽  
L Tiszlavicz ◽  
...  

2014 ◽  
Vol 52 (01) ◽  
Author(s):  
M Rau ◽  
J Schmitt ◽  
T Kudlich ◽  
JJG Marin ◽  
M Rodríguez Romero ◽  
...  
Keyword(s):  

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