Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases

1993 ◽  
Vol 46 (7) ◽  
pp. 1285-1293 ◽  
Author(s):  
Gabriella Massolini ◽  
Anne-Francoise Aubry ◽  
Angela Mcgann ◽  
Irving W. Wainer
1980 ◽  
Vol 35 (11-12) ◽  
pp. 915-918 ◽  
Author(s):  
Dieter Strack ◽  
Peter Proksch ◽  
Paul-Gerhard Gülz

High performance liquid chromatography on octyl- and octadecyl-silica (RP-8 and RP-18) stationary phases offers an efficient and rapid method for analysis of sesquiterpene lactones. A mixture of 11 lactones was analyzed using gradient elution with increasing acetonitrile concentra­tion in water and monitoring the column effluent at 210 nm with an UV detector. The described method has been applied to the determination of costunolide in a crude extract from leaves of Laurus nobilis.


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