Distribution and functional analysis of a 120- to 130-kDa T-cell surface antigen

1987 ◽  
Vol 105 (1) ◽  
pp. 161-173 ◽  
Author(s):  
Hans Yssel ◽  
Jan E. De Vries ◽  
Jannie Borst ◽  
Hergen Spits
Keyword(s):  
Functional Analysis ◽  
T Cell ◽  
Cell Surface ◽  
Surface Antigen ◽  
Cell Surface Antigen

scholarly journals Clearance of Giardia muris infection requires helper/inducer T lymphocytes.

1987 ◽  
Vol 165 (6) ◽  
pp. 1743-1748 ◽  
Author(s):  
M F Heyworth ◽  
J R Carlson ◽  
T H Ermak
Keyword(s):  
T Cells ◽  
T Cell ◽  
Cell Surface ◽  
Surface Antigen ◽  
Cytotoxic T Cells ◽  
Cell Subset ◽  
Cell Surface Antigen ◽  
T Cell Subset ◽  
Mouse Intestine ◽  
Giardia Muris

The aim of this work was to identify the T cell subset (helper/inducer or cytotoxic/suppressor) that plays a major part in the clearance of Giardia muris infection. BALB/c mice were selectively depleted of helper/inducer (Th/i) or cytotoxic/suppressor (Tc/s) T cells, by treatment with rat IgG monoclonal antibodies directed against the Th/i cell surface antigen L3T4, or against the Tc/s cell surface antigen Ly-2, and were infected with G. muris cysts. While mice depleted of Tc/s cells cleared G. muris infection at a normal rate, mice depleted of Th/i cells did not clear the infection. Depletion of the relevant T cell subset was confirmed by flow cytometry and by immunohistochemistry. The data indicate that helper/inducer T cells, but not cytotoxic T cells, are of major importance for elimination of G. muris from the mouse intestine.

A Monoclonal Antibody Specific for Bovine T Cell Surface Antigen Associated with the E-Rosette Receptor

1990 ◽  
Vol 37 (1-10) ◽  
pp. 9-18 ◽  
Author(s):  
Hiroyuki Koyama ◽  
Masato Kozakai ◽  
Satosi Kunita ◽  
Tsutomu Hohdatsu ◽  
Tomohide Nasu ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
T Cell ◽  
Cell Surface ◽  
Surface Antigen ◽  
Cell Surface Antigen

Species conservation of the T cell lymphocyte CD2 cell surface antigen

1988 ◽  
Vol 18 (8) ◽  
pp. 1223-1227 ◽  
Author(s):  
Marion H. Brown ◽  
William A. Sewell ◽  
David Y. Mason ◽  
Jonathan B. Rothbard ◽  
Michael J. Crumpton
Keyword(s):  
T Cell ◽  
Cell Surface ◽  
Surface Antigen ◽  
Species Conservation ◽  
Cell Surface Antigen
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