Chronic toxicity of styrene maleic anhydride, a male contraceptive, in rhesus monkeys ()

Contraception ◽  
1990 ◽  
Vol 42 (3) ◽  
pp. 337-347 ◽  
Author(s):  
N. Sethi ◽  
R.K. Srivastava ◽  
R.K. Singh ◽  
G.S. Bhatia ◽  
N. Sinha
Keyword(s):  
Maleic Anhydride ◽  
Rhesus Monkeys ◽  
Chronic Toxicity ◽  
Male Contraceptive ◽  
Styrene Maleic Anhydride

scholarly journals A proton NMR study of the effect of a new intravasal injectable male contraceptive RISUG on seminal plasma metabolites

Reproduction ◽  
2001 ◽  
pp. 431-436 ◽  
Author(s):  
U Sharma ◽  
K Chaudhury ◽  
NR Jagannathan ◽  
SK Guha
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Seminal Plasma ◽  
Vas Deferens ◽  
Plasma Metabolites ◽  
Obstructive Azoospermia ◽  
Male Contraceptive ◽  
Nmr Study ◽  
Significant Difference ◽  
Styrene Maleic Anhydride ◽  
Prostatic Diseases

Nuclear magnetic resonance (NMR) spectroscopy was used to quantify citrate, glucose, lactate, glycerophosphorylcholine and choline in seminal plasma from subjects injected with a new male contraceptive RISUG, a copolymer of styrene maleic anhydride dissolved in dimethyl sulphoxide, and in seminal plasma from normal ejaculates. No significant difference in the concentration of citrate was observed between the groups, indicating that the prostate is not affected by the contraceptive. The concentrations of glucose, lactate, glycerophosphorylcholine and choline were significantly lower (P < 0.01) in subjects injected with RISUG compared with controls. In addition, metabolite ratios such as choline:citrate, citrate:lactate, choline:lactate and glycerophosphorylcholine:choline were calculated. Citrate:lactate and glycerophosphorylcholine:choline ratios were significantly lower in RISUG-injected subjects than in controls (P < 0.01), thereby indicating the occurrence of partial obstructive azoospermia. The most important finding of the present study was that the intervention of RISUG in the vas deferens even for a period as long as 8 years is absolutely safe and does not lead to prostatic diseases.

Styrene-maleic anhydride copolymer esters as flow improvers of waxy crude oil

2009 ◽  
Vol 65 (3-4) ◽  
pp. 139-146 ◽  
Author(s):  
A.M. Al-Sabagh ◽  
M.R. Noor El-Din ◽  
R.E. Morsi ◽  
M.Z. Elsabee
Keyword(s):  
Maleic Anhydride ◽  
Crude Oil ◽  
Waxy Crude Oil ◽  
Waxy Crude ◽  
Styrene Maleic Anhydride ◽  
Maleic Anhydride Copolymer

Styrene-Maleic Anhydride Copolymer Esters as Flow Improvers of Waxy Crude Oil

2009 ◽  
Vol 30 (3) ◽  
pp. 420-426 ◽  
Author(s):  
A. M. Al-Sabagh ◽  
M. R. Noor El-Din ◽  
R. E. Morsi ◽  
M. Z. Elsabee
Keyword(s):  
Maleic Anhydride ◽  
Crude Oil ◽  
Waxy Crude Oil ◽  
Waxy Crude ◽  
Styrene Maleic Anhydride ◽  
Maleic Anhydride Copolymer
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