Collagen-binding proteins of rat mammary tumor epithelial cells: A biochemical and immunological study

1988 ◽  
Vol 176 (1) ◽  
pp. 20-37 ◽  
Author(s):  
Gerhard Wirl ◽  
Michael Pfäffle
Keyword(s):  
Epithelial Cells ◽  
Mammary Tumor ◽  
Binding Proteins ◽  
Immunological Study ◽  
Collagen Binding ◽  
Rat Mammary Tumor

scholarly journals Binding Sites of Droloxifene in the Cytosol of 7,12-Dimethylbenz[α]anthracene-induced Rat Mammary Tumor Cells

1994 ◽  
Vol 85 (6) ◽  
pp. 639-644
Author(s):  
Ikuo Kawamura ◽  
Elizabeth Lacey ◽  
Yoshio Tanaka ◽  
Fusako Nishigaki ◽  
Toshitaka Manda ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Mammary Tumor ◽  
Binding Sites ◽  
Mammary Tumor Cells ◽  
Rat Mammary Tumor

scholarly journals Protein F1 and Streptococcus pyogenes Resistance to Phagocytosis

2007 ◽  
Vol 75 (6) ◽  
pp. 3188-3191 ◽  
Author(s):  
Kendra A. Hyland ◽  
Beinan Wang ◽  
P. Patrick Cleary
Keyword(s):  
Epithelial Cells ◽  
Protein Expression ◽  
Streptococcus Pyogenes ◽  
Binding Proteins ◽  
M Protein ◽  
Partial Inhibition ◽  
Fibronectin Binding ◽  
Negative Mutant

ABSTRACT Streptococcus pyogenes is a major cause of pharyngitis in humans and encodes several fibronectin-binding proteins. M protein and protein F1 (PrtF1/SfbI) are differentially regulated by CO2 and O2, respectively, and both mediate the invasion of epithelial cells. This study examined whether PrtF1/SfbI shares other properties with M protein. Expression of the PrtF1/SfbI protein by an M-negative mutant conferred resistance to phagocytosis and partial inhibition of C3 deposition on the S. pyogenes surface.

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