Babesia bovis, Babesia bigemina, Babesia canis, Babesia microti and Babesia rodhaini: Comparison of ribosomal RNA gene organization

1992 ◽  
Vol 22 (6) ◽  
pp. 851-855 ◽  
Author(s):  
B.P. Dalrymple ◽  
C.M. Dimmock ◽  
F. Parrodi ◽  
I.G. Wright
Keyword(s):  
Ribosomal Rna ◽  
Gene Organization ◽  
Babesia Bovis ◽  
Babesia Microti ◽  
Babesia Canis ◽  
Babesia Bigemina ◽  
Ribosomal Rna Gene

scholarly journals Hemoparásitos en bovinos, caninos y equinos diagnosticados en el laboratorio de Parasitología de la Facultad de Medicina Veterinaria y Zootecnia de la Universidad Autónoma de Yucatan (1984-1999)

2000 ◽  
Vol 11 (4) ◽  
pp. 277-282 ◽  
Author(s):  
Roger I Rodríguez-Vivas ◽  
LA Cob-Galera ◽  
José L Domínguez-Alpizar
Keyword(s):  
Dirofilaria Immitis ◽  
Anaplasma Marginale ◽  
Babesia Bovis ◽  
Babesia Canis ◽  
Babesia Bigemina ◽  
Babesia Caballi ◽  
Babesia Equi ◽  
Animal Material ◽  
De Medicina

Introducción. Los hemoparásitos son organismos que pueden ser transmitidos a los animales domésticos por vectores mecánicos y biológicos. Su presencia en los animales domésticos produce cuadros hemáticos que afectan la salud animal. Material y métodos. Se revisaron los archivos del laboratorio de Parasitología de la Facultad de Medicina Veterinaria y Zootecnia de la Universidad Autónoma de Yucatán, de marzo de 1984 a diciembre de 1999. Se obtuvo la información de las muestras sanguíneas de bovinos, caninos y equinos que fueron remitidas y procesadas mediante las técnicas de Knott y frotis sanguíneos teñidos con Giemsa al 10%. Resultados. Se analizaron un total de 3010 muestras sanguíneas, de las cuales 2438 fueron de bovinos, 493 de caninos y 79 de equinos. Los hemoparásitos que se diagnosticaron en las distintas especies animales fueron los siguientes: bovinos: Babesia bovis (2.78%), Babesia bigemina (1.23%) y Anaplasma marginale (15.79%); caninos: Dirofilaria immitis (7.42%), Dipetalonema reconditum (5.88%) y Babesia canis (3.92%), y equinos: Babesia equi (3.79%) y Babesia caballi (2.53%). Conclusiones. Se concluye que los bovinos, caninos y equinos del estado de Yucatán se encuentran afectados por hemoparásitos que pueden afectar la salud y/o producción animal.

Unusual ribosomal RNA gene organization in copepods of the genus Calanus

1987 ◽  
Vol 196 (4) ◽  
pp. 943-946 ◽  
Author(s):  
Guy Drouin ◽  
Jason D. Hofman ◽  
W.Ford Doolittle
Keyword(s):  
Ribosomal Rna ◽  
Gene Organization ◽  
Ribosomal Rna Gene

Gene organization and primary structure of a ribosomal RNA gene cluster from Streptomyces griseus subsp. griseus

Gene ◽  
1993 ◽  
Vol 132 (1) ◽  
pp. 21-31 ◽  
Author(s):  
Kim Eunjoon ◽  
Kim Hongik ◽  
Hong Seung-Pyo ◽  
Kook Hee Kang ◽  
Yung Hee Kho ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Ribosomal Rna ◽  
Primary Structure ◽  
Streptomyces Griseus ◽  
Gene Organization ◽  
Ribosomal Rna Gene

Complete Sequence and Gene Organization of the Nosema heliothidis Ribosomal RNA Gene Region

2011 ◽  
Vol 58 (6) ◽  
pp. 539-541 ◽  
Author(s):  
SHINAN DONG ◽  
ZHONGYUAN SHEN ◽  
FENG ZHU ◽  
XUDONG TANG ◽  
LI XU
Keyword(s):  
Ribosomal Rna ◽  
Complete Sequence ◽  
Gene Organization ◽  
Gene Region ◽  
Ribosomal Rna Gene

scholarly journals Apicoplast-Targeting Antibacterials Inhibit the Growth of Babesia Parasites

2012 ◽  
Vol 56 (6) ◽  
pp. 3196-3206 ◽  
Author(s):  
Mahmoud AbouLaila ◽  
Tserendorj Munkhjargal ◽  
Thillaiampalam Sivakumar ◽  
Akio Ueno ◽  
Yuki Nakano ◽  
...  
Keyword(s):  
Growth Cycle ◽  
Inhibitory Effect ◽  
Significant Inhibition ◽  
Babesia Bovis ◽  
Babesia Microti ◽  
Babesia Bigemina ◽  
Content Type ◽  
Babesia Equi

ABSTRACTThe apicoplast housekeeping machinery, specifically apicoplast DNA replication, transcription, and translation, was targeted by ciprofloxacin, thiostrepton, and rifampin, respectively, in thein vitrocultures of fourBabesiaspecies. Furthermore, thein vivoeffect of thiostrepton on the growth cycle ofBabesia microtiin BALB/c mice was evaluated. The drugs caused significant inhibition of growth from an initial parasitemia of 1% forBabesia bovis, with 50% inhibitory concentrations (IC50s) of 8.3, 11.5, 12, and 126.6 μM for ciprofloxacin, thiostrepton, rifampin, and clindamycin, respectively. The IC50s for the inhibition ofBabesia bigeminagrowth were 15.8 μM for ciprofloxacin, 8.2 μM for thiostrepton, 8.3 μM for rifampin, and 206 μM for clindamycin. The IC50s forBabesia caballiwere 2.7 μM for ciprofloxacin, 2.7 μM for thiostrepton, 4.7 μM for rifampin, and 4.7 μM for clindamycin. The IC50s for the inhibition ofBabesia equigrowth were 2.5 μM for ciprofloxacin, 6.4 μM for thiostrepton, 4.1 μM for rifampin, and 27.2 μM for clindamycin. Furthermore, an inhibitory effect was revealed for cultures with an initial parasitemia of either 10 or 7% forBabesia bovisorBabesia bigemina, respectively. The three inhibitors caused immediate death ofBabesia bovisandBabesia equi. The inhibitory effects of ciprofloxacin, thiostrepton, and rifampin were confirmed by reverse transcription-PCR. Thiostrepton at a dose of 500 mg/kg of body weight resulted in 77.5% inhibition ofBabesia microtigrowth in BALB/c mice. These results implicate the apicoplast as a potential chemotherapeutic target for babesiosis.

scholarly journals Trichostatin A, a potential drug for treatment of animal Babesia infections

2014 ◽  
Vol 11 (2) ◽  
pp. 24-26 ◽  
Author(s):  
T Nyamjargal ◽  
N Oshima ◽  
X Xuan ◽  
I Igarashi ◽  
T Munkhjargal ◽  
...  
Keyword(s):  
Trichostatin A ◽  
Inhibitory Effect ◽  
Babesia Bovis ◽  
Babesia Microti ◽  
Control Group ◽  
Babesia Bigemina ◽  
Theileria Equi ◽  
Babesia Gibsoni

In the present study, we evaluated the inhibitory effect of trichostatin A on the asexual growth of bovine, equine, and canine Babesia parasites in vitro as well as on the in vivo growth of Babesia microti (B.microti) in mice. The growth of Babesia bovis (B.bovis), Babesia bigemina (B.bigemina), Babesia caballi (B.caballi), Theileria equi (T.equi), and Babesia gibsoni (B.gibsoni) species was significantly inhibited (P < 0.05) by very low concentrations of trichostatin A (IC50 values = 2.6, 2.4, 2.3, 2.4, and 2.3 nM, respectively). Furthermore, in B.microti-infected mice, trichostatin A caused significant higher (P < 0.05) inhibition of the growth of B.microti at the dose of 2 mg/kg body weight than that in the control group. These results indicated the trichostatin A might be a chemotherapeutic agent for treatment of babesiosis. DOI: http://dx.doi.org/10.5564/mjas.v11i2.210 Mongolian Journal of Agricultural Sciences Vol.11(2) 2013 pp.24-26

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