Flow dynamics and turbulence measurements past mitral valve prostheses in a model left ventricle: Experimental and numerical results

1992 ◽  
Vol 25 (6) ◽  
pp. 682
Author(s):  
Richard T. Schoephoerster ◽  
Krishnan B. Chandran
Author(s):  
Amber R. Mace ◽  
Pavlos P. Vlachos ◽  
Demetri P. Telionis

Long before mitral valve replacement (MVR) became a routine operation, physiologic studies indicated that the continuity of mitral leaflets with papillary muscles, chordae tendineae (CT) and the atrioventricular ring may play a decisive role in the function of the left ventricle (LV) [1]. This led Lillehei et al. [2] to establish a procedure whereby the posterior leaflet, its CT and papillary muscles were preserved in MVRs. These and other studies indicated a significant reduction of postoperative mortality compared to conventional MVR. Though developed in the early 1960s by Lillehei, the technique of chordal preservation was not initially accepted. It wasn’t until 1983 that surgeons began to revive the concept of MVR with preservation of the CT. As this technique became more widely known, many clinical studies were performed; however, very few have been conducted which examine the effect of leaflets and CT on flow dynamics.


Fluids ◽  
2021 ◽  
Vol 6 (12) ◽  
pp. 428
Author(s):  
Ghassan Maraouch ◽  
Lyes Kadem

The formation of vortex rings at valve leaflets during ventricular inflow has been a topic of interest for many years. It is generally accepted nowadays that the purpose of vortex rings is to conserve energy, reduce the workload on the heart, and minimize particle residence time. We investigated these claims by testing three different levels of annulus angle for the mitral valve: a healthy case, a slightly angled case (20°), and a highly angled case (46°). Circulation was determined to be reversed in the non-healthy case, with a dominant counterclockwise rotation instead of clockwise. Viscous energy dissipation was highest in the slightly angled case, followed by the healthy case and then the highly angled case. A Lagrangian analysis demonstrated that the healthy case resulted in the least amount of stasis, requiring eight cardiac cycles to evacuate 99% of initial ventricle volume compared to the 16 and 13 cardiac cycles required by the slightly angled and highly angled cases, respectively.


2012 ◽  
Vol 15 (5) ◽  
pp. 251
Author(s):  
Changqing Gao ◽  
Chonglei Ren ◽  
Cangsong Xiao ◽  
Yang Wu ◽  
Gang Wang ◽  
...  

<p><b>Background:</b> The purpose of this study was to summarize our experience of extended ventricular septal myectomy in patients with hypertrophic obstructive cardiomyopathy (HOCM).</p><p><b>Methods:</b> Thirty-eight patients (26 men, 12 women) with HOCM underwent extended ventricular septal myectomy. The mean age was 36.3 years (range, 18-64 years). Diagnosis was made by echocardiography. The mean (mean � SE) systolic gradient between the left ventricle (LV) and the aorta was 89.3 � 31.1 mm Hg (range, 50-184 mm Hg) according to echocardiographic assessments before the operations. Moderate or severe systolic anterior motion (SAM) of the anterior leaflet of the mitral valve was found in 38 cases, and mitral regurgitation was present in 29 cases. Extended ventricular septal myectomy was performed in all 38 cases. The results of the surgical procedures were evaluated intraoperatively with transesophageal echocardiography (TEE) and with transthoracic echocardiography (TTE) at 1 to 2 weeks after the operation. All patients were followed up with TTE after their operation.</p><p><b>Results:</b> All patients were discharged without complications. The TEE evaluations showed that the mean systolic gradient between the LV and the aorta decreased from 94.8 � 35.6 mm Hg preoperatively to 13.6 � 10.8 mm Hg postoperatively (<i>P</i> = .0000) and that the mean thickness of the ventricular septum decreased from 28.3 � 7.9 mm to 11.8 � 3.2 mm (<i>P</i> = .0000). Mitral regurgitation and SAM were significantly reduced or eliminated. During the follow-up, all patients promptly became completely asymptomatic or complained of mild effort dyspnea only, and syncope was abolished. TTE examinations showed that the postoperative pressure gradient either remained the same or diminished.</p><p><b>Conclusions:</b> Extended ventricular septal myectomy is mostly an effective method for patients with HOCM, and good surgical exposure and thorough excision of the hypertrophic septum are of paramount importance for a successful surgery.</p>


2011 ◽  
Vol 31 (9) ◽  
pp. 1388-1394 ◽  
Author(s):  
Sophia Pouriki ◽  
Alexandra Alexopoulou ◽  
Christina Chrysochoou ◽  
Leonidas Raftopoulos ◽  
George Papatheodoridis ◽  
...  

2004 ◽  
Vol 126 (6) ◽  
pp. 714-726 ◽  
Author(s):  
Olga Pierrakos ◽  
Pavlos P. Vlachos ◽  
Demetri P. Telionis

The performance of the heart after a mitral valve replacement operation greatly depends on the flow character downstream of the valve. The design and implanting orientation of valves may considerably affect the flow development. A study of the hemodynamics of two orientations, anatomical and anti-anatomical, of the St. Jude Medical (SJM) bileaflet valve are presented and compared with those of the SJM Biocor porcine valve, which served also to represent the natural valve. We document the velocity field in a flexible, transparent (LV) using time-resolved digital particle image velocimetry (TRDPIV). Vortex formation and vortex interaction are two important physical phenomena that dominate the filling and emptying of the ventricle. For the three configurations, the following effects were examined: mitral valve inlet jet asymmetry, survival of vortical structures upstream of the aortic valve, vortex-induced velocities and redirection of the flow in abidance of the Biot–Savart law, domain segmentation, resonant times of vortical structures, and regions of stagnant flow. The presence of three distinct flow patterns, for the three configurations, was identified by the location of vortical structures and level of coherence corresponding to a significant variation in the turbulence level distribution inside the LV. The adverse effect of these observations could potentially compromise the efficiency of the LV and result in flow patterns that deviate from those in the natural heart.


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