A follow-up study of the commission on chronic illness morbidity survey in baltimore —IV. Factors influencing mortality from stroke and arteriosclerotic heart disease (1954–1967)

Abstract Background The Rheumatic Heart disease in Timor Leste school students (RHD-TL) study identified Timor Leste as having some of the highest rates of definite rheumatic heart disease (RHD) in the world. The RHD-TL follow-up study aimed to assess the delivery and outcomes of the secondary prophylaxis program in known patients with echocardiographic screen detected definite and borderline RHD. Methods School-students in Timor Leste where reassessed over a 3-year period since the initial study in 2016. Prospective assessments included adherence to secondary prophylaxis, complications of prophylaxis, follow-up clinical assessment and serial echocardiography. Of the 48 patients, 25 Definite and 23 Borderline, 38 (79%) of all patients, and 92% of definite RHD cases have had one or more follow-up assessments including full datasets for adherence, recurrence rates and progression of disease. Follow-up is provided by the volunteer paediatric cardiology team and rheumatic heart disease team of two NGOs in collaboration with local clinics. Results The median duration of follow-up of the 38 patients was of 1.6 years. The median age was 13 years (range 8-22) and 75% were female. Adherence rates in patients with definite RHD was on average greater than 95% during the follow-up period. Of the 23 patients with mild or moderate RHD one case with documented acute rheumatic fever (ARF) recurrence progressed whilst 8 cases improved on benzathine-penicillin G (BPG) therapy. There was no progression of the 6 borderline cases who were not prescribed BPG. Out of the 9 borderline cases in whom BPG was prescribed, one, with 67% adherence, had a documented episode of ARF leading to echocardiographic progression and moderate definite RHD. Conclusion This was the first follow-up study to look at disease natural history, both in treated and untreated groups, in Timor-Leste and brought practical insights into the efficacy of the Timor Leste RHD monitoring and prophylaxis programs. Its ongoing project will enable advocacy and quality assessment for the program as it expands. Abstract 225 Figure 1.

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The secondary prevention for ischaemic heart disease after coronary bypass grafting – follow up study

Atherosclerosis ◽

10.1016/j.atherosclerosis.2017.06.501 ◽

2017 ◽

Vol 263 ◽

pp. e158

Author(s):

Vera Adamkova ◽

Petr Kacer ◽

Jaroslav Hubacek ◽

Ivana Kralova Lesna ◽

Vera Lanska ◽

...

Keyword(s):

Heart Disease ◽

Secondary Prevention ◽

Ischaemic Heart Disease ◽

Coronary Bypass ◽

Bypass Grafting ◽

Coronary Bypass Grafting ◽

Follow Up Study

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Comparability of risk factors for coronary heart disease among blacks and whites in the NHANES-I Epidemiologic follow-up study

Annals of Epidemiology ◽

10.1016/1047-2797(92)90008-e ◽

1992 ◽

Vol 2 (5) ◽

pp. 637-645 ◽

Cited By ~ 34

Author(s):

Richard S. Cooper ◽

Earl Ford

Keyword(s):

Risk Factors ◽

Coronary Heart Disease ◽

Heart Disease ◽

Follow Up Study ◽

Blacks And Whites ◽

Nhanes I

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Abstract TP80: Incidence And Risk Factors For The Growth And Rupture Of Unruptured Cerebral Aneurysms. Results Of Annual Radiologic Follow Up Study.

Stroke ◽

10.1161/str.44.suppl_1.atp80 ◽

2013 ◽

Vol 44 (suppl_1) ◽

Author(s):

Katsumi Matsumoto ◽

Kouichirou Tsuruzono ◽

Manabu Sasaki ◽

Noriyasu Yoshimura ◽

Toshiki Yoshimine ◽

...

Keyword(s):

Growth Rate ◽

Cerebral Aneurysms ◽

Aneurysm Rupture ◽

Annual Growth ◽

Annual Growth Rate ◽

Rupture Rate ◽

Follow Up Study ◽

Factors Influencing ◽

Unruptured Cerebral Aneurysms

Background: The recent trend of the treatment of unruptured cerebral aneurysms(UIAs) is going to be conservative. Their natural history of rupture and growth is still unkown. We present the results of annual radiological follow-up study in UIAs. Method: In recent 12 years, we have found 121patients with 148 unruptured cerebral aneurysms were followed annually using 3D-CTA or MRA. Mean follow-up period was 5.5 year. Several factors influencing rupture or growth were statistically examined. Results: Among 121 patients, 9 ruptured and 11 showed growth of UIAs. Annual rupture rate was 1.3% per year and annual growth rate was 1.6% per year. Aneurysm size was the sole factor influencing rupture(P<0.001), whereas female sex and multiplicity were major factors influencing aneurysm growth(P<0.05). Under size 3mm, annual growth rate was 3.0% whereas annual rupture rate was 0.7%. In 4-6mm, growth rate was 1.6% and rupture rate was 1.6%. In 7-9mm, growth rate was 0 and rupture rate was 5.8%. In over 10mm, growth rate was 2.9% and rupture rate was 11.6%. Within 1 year, rupture occurred in 4 cases, and growth was found in 1 case. Conclusions: By annual radiological examination, growth of UIAs was noted more frequently than aneurysm rupture. Especially UIAs under 3mm, growth was 4 times higher than rupture, radiological follow up is effective for aneurysm rupture. Within 1 year, initially found UIAs should be carefully followed in a short interval.

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