Differences in corticosterone binding by regions of the central nervous system in normal and diabetic rats

1981 ◽  
Vol 14 (1) ◽  
pp. 77-81 ◽  
Author(s):  
Silvia Tornello ◽  
Osvaldo Fridman ◽  
Liliana Weisenberg ◽  
Héctor Coirini ◽  
Alejandro F. De Nicola
Author(s):  
Klockner Géssica De Mattos Diosti ◽  
Lovato Fernanda Christo ◽  
Rebouças Rebeca Loureiro ◽  
Langer Laura Ingrid Volkweis ◽  
Hoegen Ingrid Oliveira ◽  
...  

2006 ◽  
Vol 286 (1-2) ◽  
pp. 125-131 ◽  
Author(s):  
Ozkan Ates ◽  
Suleyman R. Cayli ◽  
Eyup Altinoz ◽  
Neslihan Yucel ◽  
Ayhan Kocak ◽  
...  

2016 ◽  
Vol 68 (2-3) ◽  
pp. 103-112 ◽  
Author(s):  
Sanket N. Patel ◽  
Kashyap Pandya ◽  
George J. Clark ◽  
Mitul C. Parikh ◽  
Cesar A. Lau-Cam

2006 ◽  
Vol 31 (6) ◽  
pp. 777-783 ◽  
Author(s):  
Ozkan Ates ◽  
Neslihan Yucel ◽  
Suleyman R. Cayli ◽  
Eyup Altinoz ◽  
Saim Yologlu ◽  
...  

Author(s):  
Gladys Harrison

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.


Author(s):  
John L.Beggs ◽  
John D. Waggener ◽  
Wanda Miller ◽  
Jane Watkins

Studies using mesenteric and ear chamber preparations have shown that interendothelial junctions provide the route for neutrophil emigration during inflammation. The term emigration refers to the passage of white blood cells across the endothelium from the vascular lumen. Although the precise pathway of transendo- thelial emigration in the central nervous system (CNS) has not been resolved, the presence of different physiological and morphological (tight junctions) properties of CNS endothelium may dictate alternate emigration pathways.To study neutrophil emigration in the CNS, we induced meningitis in guinea pigs by intracisternal injection of E. coli bacteria.In this model, leptomeningeal inflammation is well developed by 3 hr. After 3 1/2 hr, animals were sacrificed by arterial perfusion with 3% phosphate buffered glutaraldehyde. Tissues from brain and spinal cord were post-fixed in 1% osmium tetroxide, dehydrated in alcohols and propylene oxide, and embedded in Epon. Thin serial sections were cut with diamond knives and examined in a Philips 300 electron microscope.


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