Assessment of membrane protection by 3 1P-NMR effects of lidocaine on calcium-paradox in myocardium

Life Sciences ◽  
1989 ◽  
Vol 45 (3) ◽  
pp. 217-222 ◽  
Author(s):  
Hirosumi Sakai ◽  
Minoru Yoshiyama ◽  
Masakazu Teragaki ◽  
Kazuhide Takeuchi ◽  
Tadanao Takeda ◽  
...  
Keyword(s):  
Calcium Paradox ◽  
Membrane Protection

Studies on the calcium paradox phenomenon in cardiac muscle strips of poikilotherms

1983 ◽  
Vol 76 (3) ◽  
pp. 601-613 ◽  
Author(s):  
Gunnel Lagerstrand ◽  
Artur Mattisson ◽  
Otakar Poupa
Keyword(s):  
Cardiac Muscle ◽  
Calcium Paradox

Protective effect of adenosine against a calcium paradox in the isolated frog heart

1992 ◽  
Vol 70 (1) ◽  
pp. 115-120 ◽  
Author(s):  
Maria Touraki ◽  
Antigone Lazou
Keyword(s):  
Protective Effect ◽  
Calcium Influx ◽  
Calcium Paradox ◽  
Mechanical Activity ◽  
Frog Heart ◽  
Dependent Manner ◽  
Myocardial Cells ◽  
Tissue Calcium ◽  
Maximum Protection ◽  
Dose Dependent

The effect of adenosine on the calcium paradox in the isolated frog heart was studied. Addition of adenosine during calcium depletion protected the frog heart against a calcium paradox. This protective effect was indicated by reduced protein and creatine kinase release, maintenance of electrical activity, and recovery of mechanical activity during reperfusion. Tissue calcium determination results showed that adenosine protected frog myocardial cells by reducing the massive calcium influx during reperfusion possibly through an action on calcium channels. Adenosine exerted its action in a dose-dependent manner; a concentration of 10 μM adenosine provided maximum protection of myocardial cells against the calcium paradox damage. Higher concentrations of adenosine produced side effects on both electrical and mechanical activity. These results are discussed in terms of the possible mechanism involved in the protective effect of adenosine.Key words: calcium paradox, adenosine, frog heart.

scholarly journals Hyperparathyroidism and the Calcium Paradox of Aldosteronism

Circulation ◽  
2005 ◽  
Vol 111 (7) ◽  
pp. 871-878 ◽  
Author(s):  
Vikram S. Chhokar ◽  
Yao Sun ◽  
Syamal K. Bhattacharya ◽  
Robert A. Ahokas ◽  
Linda K. Myers ◽  
...  
Keyword(s):  
Calcium Paradox
Sign in / Sign up

Export Citation Format

Share Document