Effective depletion of glutathione in rat striatum and substantia nigra by L-buthionine sulfoximine in combination with 2-cyclohexene-1-one

Life Sciences ◽  
1990 ◽  
Vol 47 (25) ◽  
pp. 2333-2342 ◽  
Author(s):  
Erik Pileblad ◽  
Tor Magnusson
Keyword(s):  
Substantia Nigra ◽  
Buthionine Sulfoximine ◽  
Rat Striatum

Differential Regulation of Astrocytic mRNAs in the Rat Striatum after Lesions of the Cortex or Substantia Nigra

1998 ◽  
Vol 149 (1) ◽  
pp. 87-96 ◽  
Author(s):  
P.E. Schauwecker ◽  
J.P. Cogen ◽  
T. Jiang ◽  
H.W. Cheng ◽  
T.J. Collier ◽  
...  
Keyword(s):  
Substantia Nigra ◽  
Differential Regulation ◽  
Rat Striatum

Phosphorylation of DARPP-32 Is Regulated by GABA in Rat Striatum and Substantia Nigra

2002 ◽  
Vol 63 (5) ◽  
pp. 1766-1771 ◽  
Author(s):  
Gretchen L. Snyder ◽  
Gilberto Fisone ◽  
Paul Greengard
Keyword(s):  
Substantia Nigra ◽  
Rat Striatum

Dopamine D2 receptor-mediated G-protein activation in rat striatum: functional autoradiography and influence of unilateral 6-hydroxydopamine lesions of the substantia nigra

2001 ◽  
Vol 920 (1-2) ◽  
pp. 41-54 ◽  
Author(s):  
Adrian Newman-Tancredi ◽  
Didier Cussac ◽  
Mauricette Brocco ◽  
Jean-Michel Rivet ◽  
Christine Chaput ◽  
...  
Keyword(s):  
Substantia Nigra ◽  
G Protein ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Rat Striatum ◽  
Protein Activation ◽  
Dopamine D2 ◽  
G Protein Activation ◽  
6 Hydroxydopamine

scholarly journals Changes in L1 Antigen Expression in the Rat Striatum After Substantia Nigra Lesions

1997 ◽  
Vol 6 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Maciej Poltorak ◽  
Jamesine R. Williams ◽  
Kraig D. Moore ◽  
Willam J. Freed
Keyword(s):  
Tissue Culture ◽  
Substantia Nigra ◽  
Frontal Cortex ◽  
Neurite Outgrowth ◽  
Dopaminergic Neurons ◽  
Antigen Expression ◽  
Rat Striatum ◽  
Complex Regulation ◽  
Lateral Area

L1 antigen promotes neurite outgrowth from dopaminergic neurons in tissue culture. In the present study, we examined the effects of dopaminergic deafferentation of the striatum on L1 expression. In the medial-periventricular part of the striatum, both complete and partial substantia nigra (SN) lesions decreased L1 expression. Complete lesions increased L1 expression in the dorso-medial and ventrolateral parts of the striatum on the lesioned side when compared with that on the non-lesioned side. The decrease in the ventro-lateral area was maintained in animals examined three months after the lesioning. Animals with partial SN lesions showed a different pattern of altered L1 expression. After frontal cortex lesions, changes in L1 expression also occur preferentially in the dorso-medial and periventricular striatum. Therefore, the results indicate a complex regulation of L1 expression after damage of striatal circuitry, manifested by a preferential occurrence of changes in periventricular regions.

Sign in / Sign up

Export Citation Format

Share Document