Detection of small for gestational age fetuses by the combination of clinical risk factors and ultrasonography

The relationships and predictive abilities of perceived stress, selected clinical risk factors, and corticotropin-releasing hormone (CRH) levels in maternal plasma were investigated for their association with preterm labor (PTL), preterm birth, and gestational age at delivery. An exploratory, prospective, longitudinal research design was used to measure CRH 4 times over pregnancy, perceived stress at 24 and 32 weeks of pregnancy, clinical risk factors, and genitourinary infections in low-income women. Multiple regression analyses revealed that a model of measurement of perceived stress at 24 or 32 weeks, CRH at 24 or 32 weeks, and PTL (indicated by a diagnosis by the physicians on the medical record and greater than 5 contractions per hour on the fetal monitor) was predictive of as much as 0.23 to 0.27 of the variance in gestational age at birth. Entering ethnicity as a variable into a model did not improve the predictive value. An analysis of variance between Caucasian and Hispanic ethnic groups revealed differences in CRH levels. However, simple regression analysis of ethnicity as a predictor showed a weak r 2 with no significance for prediction. There was some evidence of an association of smoking with stress and both PTL and preterm birth. The measurement of stress combined with the measurement of CRH from maternal plasma may improve the prediction of which pregnant women are at risk for preterm birth. The measurement of CRH has potential as an early biological marker of preterm birth.

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438 Predictive impact of clinical risk factors and the inducibility of ventricular fibrillation in patients with an asymptomatic Brugada-type ECG

EP Europace ◽

10.1016/s1099-5129(05)80290-9 ◽

2005 ◽

Vol 7 ◽

pp. 98-98

Keyword(s):

Risk Factors ◽

Ventricular Fibrillation ◽

Clinical Risk Factors ◽

Clinical Risk

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RISK FACTORS FOR SMALL FOR GESTATIONAL AGE INFANTS: A STUDY BASED ON THE ARKHANGELSK COUNTY BIRTH REGISTRY

PEDIATRIA Journal named after G N SPERANSKY ◽

10.24110/0031-403x-2020-99-1-32-39 ◽

2020 ◽

Vol 99 (1) ◽

pp. 32-39

Author(s):

A.A. Usynina ◽

◽

G.N. Chumakova ◽

V.A. Postoev ◽

J.O. Odland ◽

...

Keyword(s):

Risk Factors ◽

Gestational Age ◽

Small For Gestational Age ◽

Birth Registry

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The impact of standard clinical risk factors on determination of optimal mammographic density cutpoints

10.26226/morressier.5ade45fdd462b8029238e7dc ◽

2018 ◽

Author(s):

Sian Iles

Keyword(s):

Risk Factors ◽

Mammographic Density ◽

Clinical Risk Factors ◽

Clinical Risk ◽

The Impact

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Faculty Opinions recommendation of Molecular and clinical risk factors for recurrence of skull base chordomas: gain on chromosome 2p, expression of brachyury, and lack of irradiation negatively correlate with patient prognosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718084150.793526065 ◽

2016 ◽

Author(s):

Carlos Bagley

Keyword(s):

Risk Factors ◽

Skull Base ◽

Clinical Risk Factors ◽

Clinical Risk ◽

Risk Factors For Recurrence ◽

Skull Base Chordomas ◽

Patient Prognosis

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Long-Term Follow-Up of Patients With Isolated Side Branch Coronary Artery Disease

Angiology ◽

10.1177/00033197211028024 ◽

2021 ◽

pp. 000331972110280

Author(s):

Sukru Arslan ◽

Ahmet Yildiz ◽

Okay Abaci ◽

Urfan Jafarov ◽

Servet Batit ◽

...

Keyword(s):

Risk Factors ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Vessel Diameter ◽

Side Branch ◽

Clinical Risk Factors ◽

Clinical Risk ◽

Artery Disease

The data with respect to stable coronary artery disease (SCAD) are mainly confined to main vessel disease. However, there is a lack of information and long-term outcomes regarding isolated side branch disease. This study aimed to evaluate long-term major adverse cardiac and cerebrovascular events (MACCEs) in patients with isolated side branch coronary artery disease (CAD). A total of 437 patients with isolated side branch SCAD were included. After a median follow-up of 38 months, the overall MACCE and all-cause mortality rates were 14.6% and 5.9%, respectively. Among angiographic features, 68.2% of patients had diagonal artery and 82.2% had ostial lesions. In 28.8% of patients, the vessel diameter was ≥2.75 mm. According to the American College of Cardiology lesion classification, 84.2% of patients had either class B or C lesions. Age, ostial lesions, glycated hemoglobin A1c, and neutrophil levels were independent predictors of MACCE. On the other hand, side branch location, vessel diameter, and lesion complexity did not affect outcomes. Clinical risk factors seem to have a greater impact on MACCE rather than lesion morphology. Therefore, the treatment of clinical risk factors is of paramount importance in these patients.

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Extensive Perivillous Fibrin and Intervillous Histiocytosis in a SARS-CoV-2 Infected Placenta From an Uninfected Newborn: A Case Report Including Immunohistochemical Profiling

Pediatric and Developmental Pathology ◽

10.1177/10935266211025122 ◽

2021 ◽

pp. 109352662110251

Author(s):

James Roberts ◽

Jeanette D Cheng ◽

Elizabeth Moore ◽

Carla Ransom ◽

Minhui Ma ◽

...

Keyword(s):

Risk Factors ◽

Case Report ◽

Gestational Age ◽

Small For Gestational Age ◽

Immunohistochemical Staining ◽

Placental Pathology ◽

Fibrin Deposition ◽

Placental Infection ◽

Fetal Infection

Placental infection by SARS-CoV-2 with various pathologic alterations reported. Inflammatory findings, such as extensive perivillous fibrin deposition and intervillous histiocytosis, have been postulated as risk factors for fetal infection by SARS-CoV-2. We describe the placental findings in a case of a 31-year-old mother with SARS-CoV-2 infection who delivered a preterm female neonate who tested negative for SAR-CoV2 infection. Placental examination demonstrated a small for gestational age placenta with extensive intervillous histiocytosis, syncytiotrophoblast karyorrhexis, and diffuse intervillous fibrin deposition. Immunohistochemical staining demonstrated infection of the syncytiotrophoblasts by SARS-CoV-2 inversely related to the presence of intervillous histiocytes and fibrin deposition. Our case demonstrates that despite extensive placental pathology, no fetal transmission of SARS-CoV-2 occurred, as well as postulates a relationship between placental infection, inflammation, and fibrin deposition.

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