Studies on Mediterranean leishmaniasis IV. The leishmanin skin test in cutaneous leishmaniasis

Author(s):  
S. Pampiglione ◽  
P.E.C. Manson-Bahr ◽  
M. La Placa ◽  
M.A. Borgatti ◽  
F. Micheloni
2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Mohammed Musid Alkulaibi ◽  
Ahmed Mohamed Suleiman ◽  
Eltahir Awad Gasim Khalil ◽  
Maged Ahmed Al-Garadi

Leishmaniasis in Yemen is still not fully investigated nor well studied. Recently, outbreaks of cutaneous leishmaniasis (CL) in western highland were declared. However, there are no reports concerning the disease and the circulating species in the region. The aim of this study was to determine the prevalence of cutaneous leishmaniasis in Utmah district located in Western Highlands in Yemen. A cross-sectional survey was carried out at those highlands. For the survey, 1165 participants were subjected to Leishmanin Skin Test (LST) accompanied with direct interviews and physical examination. The overall prevalence of cutaneous leishmaniasis in the district was 18.5% and the cutaneous leishmaniasis (CL) was more frequent in the escarpments with a prevalence of 37%, including 5.5% for active lesion and 31.5% for scar of healed lesions. Children under the age of 16 years old comprised most of the CL cases (76.3%). The escarpments of western highlands in Yemen were hyperendemic areas for CL and the infection was more prevalent in children.


2020 ◽  
Vol 114 (6) ◽  
pp. 433-439
Author(s):  
Annhymariet Torrellas ◽  
Elizabeth Ferrer ◽  
Israel Cruz ◽  
Hector De Lima ◽  
Rafael Borges ◽  
...  

Abstract Background Little is known about the prevalence of asymptomatic leishmaniasis in Venezuela. The objective of this study was to quantify Leishmania asymptomatic infection in six endemic foci of cutaneous leishmaniasis (CL) in Portuguesa State, Venezuela, where no previous data were available. Methods Study of the prevalence of Leishmania asymptomatic infection was carried out in 841 individuals from six endemic foci of CL in the municipalities Sucre and Ospino, Portuguesa State. We applied the leishmanin skin test (LST) and the internal transcribed spacer 1 (ITS1) PCR to DNA from sera and blood clots of all LST-positive and 20% of LST-negative patients. Results Of 841 inhabitants tested by LST, 197 returned a positive reaction (23.42%); all of the LST-positives (197) and 121 negatives were screened by nested PCR using serum and blood clots. Among the LST-positive group, 2.54% were PCR-positive with sera, while 44.67% were positive with blood clots. In the LST-negative group, PCR was positive in 2.48% of serum samples and in 38.84% of blood clots. Conclusions It is recommended that LST and PCR on blood clots are used together to detect exposure and asymptomatic infection and for identification of the Leishmania species.


2002 ◽  
Vol 44 (2) ◽  
pp. 105-107 ◽  
Author(s):  
Ismery CABELLO ◽  
Alejandro CARABALLO ◽  
Yaneth MILLÁN

Two patients from the gold mines of Bolivar State, Venezuela, presenting cutaneous leishmaniasis in the genital region, an unusual location, are described. The first patient showed an ulcerated lesion of the glans penis. Leishmanin skin test was positive. A biopsy specimen revealed a granulomatous infiltrate containing Leishmania parasites. In the second patient, Leishmanin skin test was positive, HIV and VDRL were negative. Leishmania parasites were present in a biopsy of an ulcerated lesion in the scrotum, with an indurated base, infiltrative borders with an yellowish exudate. Patients were treated with meglumine antimoniate and the lesions healed.


2017 ◽  
Vol 11 (10) ◽  
pp. e0005980 ◽  
Author(s):  
Alejandro Javier Krolewiecki ◽  
Maria Cristina Almazan ◽  
Marcelo Quipildor ◽  
Marisa Juarez ◽  
Jose Fernando Gil ◽  
...  

2013 ◽  
Vol 58 (3) ◽  
pp. 239 ◽  
Author(s):  
Giti Sadeghian ◽  
Hengameh Ziaei ◽  
LeilaShirani Bidabadi ◽  
MohammadAli Nilforoushzadeh

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