Humoral immune response elicited by highly attenuated variants of vaccinia virus and by an attenuated recombinant expressing HIV-1 envelope protein

Virology ◽  
1989 ◽  
Vol 173 (1) ◽  
pp. 323-329 ◽  
Author(s):  
Shatha Dallo ◽  
Juehn-Shin Maa ◽  
Juan-Ramon Rodriguez ◽  
Dolores Rodriguez ◽  
Mariano Esteban
Keyword(s):  
Immune Response ◽  
Vaccinia Virus ◽  
Humoral Immune Response ◽  
Envelope Protein ◽  
Humoral Immune ◽  
Hiv 1

Characterization of the HIV-1 Specific Humoral Immune Response During Highly Active Antiretroviral Therapy (HAART)

2001 ◽  
Vol 28 (5) ◽  
pp. 405-415 ◽  
Author(s):  
Mary Kate Morris ◽  
David A. Katzenstein ◽  
Dennis Israelski ◽  
Andrew Zolopa ◽  
R. Michael Hendry ◽  
...  
Keyword(s):  
Immune Response ◽  
Antiretroviral Therapy ◽  
Humoral Immune Response ◽  
Highly Active Antiretroviral Therapy ◽  
Humoral Immune ◽  
Highly Active ◽  
Hiv 1

scholarly journals HIV-1 Tat Raises an Adjuvant-free Humoral Immune Response Controlled by Its Core Region and Its Ability to Form Cysteine-mediated Oligomers

2005 ◽  
Vol 281 (6) ◽  
pp. 3105-3115 ◽  
Author(s):  
Jongrak Kittiworakarn ◽  
Alain Lecoq ◽  
Gervaise Moine ◽  
Robert Thai ◽  
Evelyne Lajeunesse ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Core Region ◽  
Humoral Immune ◽  
Hiv 1

scholarly journals DNA Encoding an HIV-1 Gag/Human Lysosome-Associated Membrane Protein-1 Chimera Elicits a Broad Cellular and Humoral Immune Response in Rhesus Macaques

PLoS ONE ◽  
2006 ◽  
Vol 1 (1) ◽  
pp. e135 ◽  
Author(s):  
Priya Chikhlikar ◽  
Luciana Barros de Arruda ◽  
Milton Maciel ◽  
Peter Silvera ◽  
Mark G. Lewis ◽  
...  
Keyword(s):  
Immune Response ◽  
Membrane Protein ◽  
Humoral Immune Response ◽  
Rhesus Macaques ◽  
Dna Encoding ◽  
Humoral Immune ◽  
Hiv 1

scholarly journals Sequential immunizations with rgp120s from independent isolates of human immunodeficiency virus type 1 induce the preferential expansion of broadly crossreactive B cells.

1991 ◽  
Vol 173 (4) ◽  
pp. 881-887 ◽  
Author(s):  
D M Klinman ◽  
K W Higgins ◽  
J Conover
Keyword(s):  
Immune Response ◽  
Human Immunodeficiency Virus ◽  
B Cells ◽  
Human Immunodeficiency Virus Type ◽  
Humoral Immune Response ◽  
Envelope Glycoprotein ◽  
Humoral Immune ◽  
Immunodeficiency Virus ◽  
Hiv 1

The gp120 envelope glycoprotein of human immunodeficiency virus type 1 (HIV-1) is a dominant target against which the host's humoral immune response is directed. Unfortunately, gp120 proteins from different isolates of HIV are antigenically distinct, complicating the use of the envelope glycoprotein in vaccines designed to prevent acquired immunodeficiency syndrome. Using an enzyme-linked immunosorbent spot assay (ELISA), BALB/c mice immunized and boosted with recombinant purified gp120 were studied at the single cell level for their humoral immune response to HIV-1 envelope proteins. Approximately 90% of responding B cells produced antibodies reactive with the immunizing form of gp120 but not with gp120s from other strains of HIV. A novel sandwich ELISA was then used to analyze the frequency with which individual in vivo activated B cells produced antibodies that crossreacted with heterologous gp120s. Repeated immunizations with a single gp120 or with a mixture of different gp120s resulted in the activation of primarily mono-specific (noncrossreactive) B cells. In contrast, the sequential immunization of mice with recombinant purified envelope proteins from different strains of HIV (IIIB, SF2, and Zr6) induced the selective expansion of B cells producing highly crossreactive antibodies.

Long-lasting humoral immune response induced in HIV-1-infected patients by a synthetic peptide (AT20) derived from the HIV-1 matrix protein p17 functional epitope

2015 ◽  
Vol 16 (4) ◽  
pp. 157-162 ◽  
Author(s):  
Emanuele Focà ◽  
Maria Luisa Iaria ◽  
Francesca Caccuri ◽  
Simona Fiorentini ◽  
Davide Motta ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Synthetic Peptide ◽  
Matrix Protein ◽  
Humoral Immune ◽  
Hiv 1

Mother to child transmission of HIV-1 in a Thai population: Role of virus characteristics and maternal humoral immune response

2009 ◽  
Vol 81 (5) ◽  
pp. 768-778 ◽  
Author(s):  
Chonticha Kittinunvorakoon ◽  
Mary Kate Morris ◽  
Kanchana Neeyapun ◽  
Bongkoch Jetsawang ◽  
Gertrude C. Buehring ◽  
...  
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Thai Population ◽  
Humoral Immune ◽  
Mother To Child ◽  
Hiv 1
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