City air pollution of polycyclic aromatic hydrocarbons and other mutagens: occurrence, sources and health effects

1996 ◽  
Vol 189-190 ◽  
pp. 41-49 ◽  
Author(s):  
Torben Nielsen ◽  
Hans E. Jørgensen ◽  
John Chr. Larsen ◽  
Morten Poulsen
Keyword(s):  
Air Pollution ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Health Effects ◽  
Aromatic Hydrocarbons ◽  
Polycyclic Aromatic

scholarly journals Exposure to Atmospheric Particulate Matter-Bound Polycyclic Aromatic Hydrocarbons and Their Health Effects: A Review

2021 ◽  
Vol 18 (4) ◽  
pp. 2177
Author(s):  
Lu Yang ◽  
Hao Zhang ◽  
Xuan Zhang ◽  
Wanli Xing ◽  
Yan Wang ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Particulate Matter ◽  
Real Time ◽  
Health Effects ◽  
Aromatic Hydrocarbons ◽  
Anthropogenic Activities ◽  
Personal Exposure ◽  
Epidemiological Studies ◽  
Atmospheric Particulate Matter ◽  
Polycyclic Aromatic

Particulate matter (PM) is a major factor contributing to air quality deterioration that enters the atmosphere as a consequence of various natural and anthropogenic activities. In PM, polycyclic aromatic hydrocarbons (PAHs) represent a class of organic chemicals with at least two aromatic rings that are mainly directly emitted via the incomplete combustion of various organic materials. Numerous toxicological and epidemiological studies have proven adverse links between exposure to particulate matter-bound (PM-bound) PAHs and human health due to their carcinogenicity and mutagenicity. Among human exposure routes, inhalation is the main pathway regarding PM-bound PAHs in the atmosphere. Moreover, the concentrations of PM-bound PAHs differ among people, microenvironments and areas. Hence, understanding the behaviour of PM-bound PAHs in the atmosphere is crucial. However, because current techniques hardly monitor PAHs in real-time, timely feedback on PAHs including the characteristics of their concentration and composition, is not obtained via real-time analysis methods. Therefore, in this review, we summarize personal exposure, and indoor and outdoor PM-bound PAH concentrations for different participants, spaces, and cities worldwide in recent years. The main aims are to clarify the characteristics of PM-bound PAHs under different exposure conditions, in addition to the health effects and assessment methods of PAHs.

scholarly journals Amino-PAHs activated Nrf2/ARE anti-oxidative defense system and promoted inflammatory responses: the regulation of PI3K/Akt pathway

2018 ◽  
Vol 7 (3) ◽  
pp. 465-472 ◽  
Author(s):  
Meiying Wu ◽  
Yuting Jiang ◽  
Mingyuan Liu ◽  
Yu Shang ◽  
Jing An
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Health Effects ◽  
Aromatic Hydrocarbons ◽  
Inflammatory Responses ◽  
Akt Pathway ◽  
Defense System ◽  
Oxidative Defense ◽  
Polycyclic Aromatic

The amino polycyclic aromatic hydrocarbons (amino-PAHs) were frequently detected in PM2.5, and it was suggested that they contributed to the harmful health effects associated with PM2.5.

scholarly journals Air Pollution and Neuropsychological Development: A Review of the Latest Evidence

Endocrinology ◽  
2015 ◽  
Vol 156 (10) ◽  
pp. 3473-3482 ◽  
Author(s):  
Elisabet Suades-González ◽  
Mireia Gascon ◽  
Mònica Guxens ◽  
Jordi Sunyer
Keyword(s):  
Autism Spectrum Disorder ◽  
Air Pollution ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Nitrogen Oxides ◽  
Aromatic Hydrocarbons ◽  
Autism Spectrum ◽  
Postnatal Exposure ◽  
Outdoor Air ◽  
Neuropsychological Development ◽  
Polycyclic Aromatic

For the last decade, literature on the detrimental impacts of air pollution on brain, cognition and behavior has exponentially increased. Our aim is to review the latest epidemiologic literature on the association between outdoor air pollution and neuropsychological developmental in children. Two independent researchers searched for published studies between January 1, 2012 and June 12, 2015 in MEDLINE, Web of Science, and Science direct using defined keywords on outdoor air pollution and neuropsychological development. Selection of articles was based on study eligibility criteria. We encountered sufficient evidence of detrimental effects of pre- or postnatal exposure to polycyclic aromatic hydrocarbons on global intelligence quotient. The evidence was also sufficient for the association between pre- or postnatal exposure to fine particulate matter (PM2.5) and autism spectrum disorder, and limited evidence was encountered between nitrogen oxides and autism spectrum disorder. For other exposure-outcome associations reviewed, the evidence was inadequate or insufficient. Although evidence is not yet conclusive and further research is needed, the latest epidemiological studies support the hypothesis that pre- or postnatal exposure to ambient pollution, particularly polycyclic aromatic hydrocarbons, PM2.5, and nitrogen oxides has a negative impact on the neuropsychological development of children. The public health impact of air pollutants cannot be ignored and the precautionary principle should be applied to protect children.

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